Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	1-deoxynojirimycin	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
2	1-deoxynojirimycin hydrochloride	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
3	A-glucosidasi acida umana ricombinante coniugata con multiple copie di bis-mannosio-6- fosfato-tetra-mannosio glicano sintetico (neogaa)	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
4	Aav2/8lsphgaa	-	-	-	-	1件: 256 💬
5	Acetaminophen	Acetaminophen	1件: D00217 💬	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	14件: 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
6	Albuterol	Salbutamol	1件: D02147 💬	1件: ADRB2 💬	8件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	8件: 12, 13, 86, 89, 113, 231, 256, 299 💬
7	Aldurazyme (laronidase)	Laronidase	1件: D04670 💬	1件: IDUA 💬	3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways	2件: 19, 256 💬
8	Alglucosidase alfa	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
9	Alglucosidase alfa (genetical recombination)	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
10	Alglucosidase alfa (gz419829)	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
11	Alglucosidase alfa (myozyme)	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
12	Alglucosidase alfa (recombinant human acid alpha-glucosidase [rhgaa])	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
13	Alglucosidase alfa gz419829	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
14	Alglucosidase alpha	-	-	-	-	1件: 256 💬
15	Alpha-glucosidase	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
16	At2220	AT2220	-	-	-	1件: 256 💬
17	At2221	-	-	-	-	1件: 256 💬
18	At2221 65 mg formulated capsules	-	-	-	-	1件: 256 💬
19	At845	-	-	-	-	1件: 256 💬
20	Atb200	-	-	-	-	1件: 256 💬
21	Avalglucosidase alfa	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
22	Avalglucosidase alfa (neogaa)	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
23	Avalglucosidase alfa gz402666	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
24	Avalglucosidase alfa(gz402666)	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
25	Beta-hydroxybuturate esters	-	-	-	-	1件: 256 💬
26	Bmn 701	-	-	-	-	1件: 256 💬
27	Bortezomib	Bortezomib	1件: D03150 💬	1件: PSMB5 💬	8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
28	Cipaglucosidase alfa	-	-	-	-	1件: 256 💬
29	Clenbuterol	Clenbuterol	1件: D07713 💬	1件: ADRB2 💬	8件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	4件:  1 ,  2 ,  6 , 256 💬
30	Cyclophosphamide	Cyclophosphamide	2件: D00287, D07760 💬	-	-	44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
31	Cyclophosphamide monohydrate	Cyclophosphamide	2件: D00287, D07760 💬	-	-	4件: 13, 60, 96, 256 💬
32	Deoxynojirimycin	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
33	Deprakine	-	-	-	-	1件: 256 💬
34	Diphenhydramine	Diphenhydramine	6件: D00300, D00669, D02419, D03285, D03360, D03854 💬	1件: HRH1 💬	3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
35	Duvoglustat	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
36	Duvoglustat hcl	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
37	Duvoglustat hydrochloride	Duvoglustat	1件: D09605 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
38	Enzyme replacement agent	-	-	-	-	1件: 256 💬
39	Epilim	-	-	-	-	1件: 256 💬
40	Epilim chrono 200 controlled released tablets	-	-	-	-	1件: 256 💬
41	Epilim chrono 300 controlled released tablets	-	-	-	-	1件: 256 💬
42	Epilim chrono 500 controlled released tablets	-	-	-	-	1件: 256 💬
43	Filgrastim	Filgrastim	1件: D03235 💬	1件: CSF3R 💬	5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	27件:  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
44	Genetic: recombinant adeno-associated virus acid alpha-glucosidase	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
45	Gilt-rhgaa	-	-	-	-	1件: 256 💬
46	Glucosidase alfa	-	-	-	-	1件: 256 💬
47	Glycosade	-	-	-	-	3件: 65, 256, 257 💬
48	Gz402666	-	-	-	-	1件: 256 💬
49	Intravenous immune globulin	-	-	-	-	1件: 256 💬
50	Ketocal 4:1 liquid nutricia (intervention)	-	-	-	-	1件: 256 💬
51	Laronidase	Laronidase	1件: D04670 💬	1件: IDUA 💬	3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways	2件: 19, 256 💬
52	Lidocaine	Lidocaine	3件: D00358, D02086, D08127 💬	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	10件:  6 , 13, 34, 46, 51, 86, 168, 226, 231, 256 💬
53	Lmx 4 topical cream	-	-	-	-	1件: 256 💬
54	Low carbohydrate ketogenic diet	-	-	-	-	1件: 256 💬
55	Lumizyme	-	-	-	-	1件: 256 💬
56	Lumizyme®	-	-	-	-	1件: 256 💬
57	Mannose	Mannose	-	-	-	2件: 13, 256 💬
58	Methotrexate	Methotrexate	2件: D00142, D02115 💬	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
59	Methotrexate sodium	Methotrexate	2件: D00142, D02115 💬	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	2件: 46, 256 💬
60	Miglustat	Miglustat	1件: D05032 💬	1件: UGCG 💬	2件: Metabolic pathways, Sphingolipid metabolism	3件: 19, 256, 299 💬
61	Miglustat (at2221)	Miglustat	1件: D05032 💬	1件: UGCG 💬	2件: Metabolic pathways, Sphingolipid metabolism	1件: 256 💬
62	Myozyme	-	-	-	-	1件: 256 💬
63	Myozyme 50 mg powder for concentrate for solution for infusion	-	-	-	-	1件: 256 💬
64	Myozyme®	-	-	-	-	1件: 256 💬
65	Myozyme® (alglucosidase alfa)	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
66	N.a.	-	-	-	-	10件:  3 ,  6 ,  8 , 13, 46, 96, 97, 240, 256, 271 💬
67	Neo-gaa	-	-	-	-	1件: 256 💬
68	Neogaa	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
69	Neogaa or avalglucosidase alfa	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
70	Other: no treatment	-	-	-	-	2件: 53, 256 💬
71	Other: rmst	-	-	-	-	1件: 256 💬
72	Other: saline	-	-	-	-	8件:  2 ,  6 , 46, 97, 98, 256, 274, 301 💬
73	Phosphate	Phosphate ion	-	-	-	30件:  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
74	Plecebo	-	-	-	-	1件: 256 💬
75	Pyridostigmine	Pyridostigmine	1件: D00487 💬	1件: ACHE 💬	2件: Cholinergic synapse, Glycerophospholipid metabolism	4件:  3 ,  6 , 11, 256 💬
76	Pyridostigmine bromide	Pyridostigmine	1件: D00487 💬	1件: ACHE 💬	2件: Cholinergic synapse, Glycerophospholipid metabolism	3件:  3 ,  6 , 256 💬
77	Raav1-cmv-gaa (study agent) administration	-	-	-	-	1件: 256 💬
78	Rapamycin	Sirolimus	1件: D00753 💬	1件: MTOR 💬	50件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway	18件:  2 , 15, 34, 35, 46, 49, 51, 60, 61, 67, 86, 89, 96, 157, 158, 256, 278, 279 💬
79	Recombinant human ?-glucosidase conjugated with synthetic bismannose-6-phosphate-man6 glycan	Phosphate ion	-	-	-	1件: 256 💬
80	Recombinant human a-glucosidase conjugated with multiple copies of synthetic bis-mannose-6-phosphate-tetra-mannose glycan (neogaa)	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
81	Recombinant human a-glucosidase conjugated with multiple copies of synthetic bis-mannose-6-phosphate-tetra-mannose glycan avalglucosidase alfa (neogaa)	Avalglucosidase alfa	1件: D11744 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
82	Recombinant human acid alfa-glucosidase	-	-	-	-	1件: 256 💬
83	Recombinant human acid alfa-glucosidase (atb200)	-	-	-	-	1件: 256 💬
84	Recombinant human acid alfa-glucosidase (rhgaa)	-	-	-	-	1件: 256 💬
85	Recombinant human acid alpha-glucosidase (rhgaa)	Alglucosidase alfa	1件: D03207 💬	1件: GAA 💬	4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	1件: 256 💬
86	Ren001	ReN001	-	-	-	1件: 256 💬
87	Reveglucosidase alfa	-	-	-	-	1件: 256 💬
88	Reveglucosidase alpha	-	-	-	-	1件: 256 💬
89	Rhgaa	-	-	-	-	1件: 256 💬
90	Rhgaa, acid alpha glucosidase	-	-	-	-	1件: 256 💬
91	Rituxan	-	-	-	-	4件: 46, 60, 256, 288 💬
92	Rituximab	Rituximab	1件: D02994 💬	1件: MS4A1 💬	1件: Hematopoietic cell lineage	47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
93	Salbutamol	Salbutamol	1件: D02147 💬	1件: ADRB2 💬	8件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	9件:  3 , 11, 49, 85, 86, 111, 228, 256, 299 💬
94	Sodium valproate	Valproic acid	1件: D00399 💬	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	4件:  2 , 90, 102, 256 💬
95	Spk-3006	-	-	-	-	1件: 256 💬
96	Ss-hydroxybuturate esters	-	-	-	-	1件: 256 💬
97	Triheptanoin	Triheptanoin	1件: D11465 💬	-	-	9件:  2 ,  8 , 149, 156, 248, 256, 257, 317, 324 💬
98	Ux007	-	-	-	-	4件:  8 , 248, 256, 257 💬
99	Val-1221	-	-	-	-	1件: 256 💬
100	Valproate	Valproic acid	1件: D00399 💬	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	6件:  2 ,  3 , 90, 102, 233, 256 💬
101	Valproic acid	Valproic acid	1件: D00399 💬	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	10件:  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬
102	Zavesca	-	-	-	-	3件: 19, 256, 299 💬
103	Zavesca® prescription	-	-	-	-	1件: 256 💬

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