DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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107 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: RARA 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
2	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
3	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
4	African trypanosomiasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
6	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
7	Allograft rejection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
8	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
9	Alzheimer disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
10	Amoebiasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
11	Amphetamine addiction 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
12	AMPK signaling pathway 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
13	AMPK signaling pathway 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
14	AMPK signaling pathway 💬	1件: HMGCR 💬	D00359 💬	Lovastatin	11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
15	AMPK signaling pathway 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
16	Amyotrophic lateral sclerosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
17	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
18	Antifolate resistance 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
19	Antigen processing and presentation 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
20	Apoptosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
21	Arachidonic acid metabolism 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
22	Asthma 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
23	Autoimmune thyroid disease 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
24	Axon guidance 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
25	B cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
26	Bile secretion 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
27	Bile secretion 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
28	Bile secretion 💬	1件: HMGCR 💬	D00359 💬	Lovastatin	11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
29	Bile secretion 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
30	C-type lectin receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
31	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
32	Calcium signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
33	cAMP signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
34	Cell adhesion molecules 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
35	Cellular senescence 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
36	cGMP-PKG signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
37	Chagas disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
38	Coronavirus disease - COVID-19 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
39	Cytokine-cytokine receptor interaction 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
40	Cytokine-cytokine receptor interaction 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
41	Cytokine-cytokine receptor interaction 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
42	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
43	Dilated cardiomyopathy 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
44	Dopaminergic synapse 💬	3件: PPP3CA, PPP3CB, PPP3CC 💬	D05480 💬	Pimecrolimus	1件: 160 💬
45	Epstein-Barr virus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
46	Estrogen signaling pathway 💬	1件: RARA 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
47	Fc epsilon RI signaling pathway 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
48	Fc epsilon RI signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
49	Fluid shear stress and atherosclerosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
50	Gastric cancer 💬	1件: RARB 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
51	Glucagon signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
52	Glucagon signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
53	Glutamatergic synapse 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
54	Graft-versus-host disease 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
55	Graft-versus-host disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
56	Hematopoietic cell lineage 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
57	Hematopoietic cell lineage 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
58	Hepatitis B 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
59	Hepatitis C 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
60	Hepatitis C 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
61	Herpes simplex virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
62	Human cytomegalovirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
63	Human cytomegalovirus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
64	Human immunodeficiency virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
65	Human immunodeficiency virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
66	Human papillomavirus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
67	Human T-cell leukemia virus 1 infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
68	Human T-cell leukemia virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
69	Hypertrophic cardiomyopathy 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
70	IL-17 signaling pathway 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
71	IL-17 signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
72	Inflammatory bowel disease 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
73	Inflammatory bowel disease 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
74	Inflammatory bowel disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
75	Influenza A 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
76	Insulin resistance 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
77	Insulin resistance 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
78	Intestinal immune network for IgA production 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
79	JAK-STAT signaling pathway 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
80	Kaposi sarcoma-associated herpesvirus infection 💬	1件: CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
81	Kaposi sarcoma-associated herpesvirus infection 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
82	Legionellosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
83	Leishmaniasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
84	Long-term potentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
85	Malaria 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
86	MAPK signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
87	MAPK signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
88	Metabolic pathways 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
89	Metabolic pathways 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
90	Metabolic pathways 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
91	Metabolic pathways 💬	1件: HMGCR 💬	D00359 💬	Lovastatin	11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
92	Metabolic pathways 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
93	mTOR signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
94	Natural killer cell mediated cytotoxicity 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
95	Natural killer cell mediated cytotoxicity 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
96	Necroptosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
97	NF-kappa B signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
98	NOD-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
99	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
100	Non-alcoholic fatty liver disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
101	Non-small cell lung cancer 💬	1件: RARB 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
102	Oocyte meiosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
103	Osteoclast differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
104	Osteoclast differentiation 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
105	Ovarian steroidogenesis 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
106	Oxytocin signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
107	Pathogenic Escherichia coli infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
108	Pathways in cancer 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
109	Pathways in cancer 💬	2件: RARA, RARB 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
110	Pathways of neurodegeneration - multiple diseases 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
111	Pathways of neurodegeneration - multiple diseases 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
112	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
113	Pertussis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
114	PI3K-Akt signaling pathway 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
115	PPAR signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
116	Prion disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
117	Prion disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
118	Proteoglycans in cancer 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
119	Renin secretion 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
120	Rheumatoid arthritis 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
121	Rheumatoid arthritis 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
122	Rheumatoid arthritis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
123	RIG-I-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
124	Salmonella infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
125	Serotonergic synapse 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
126	Shigellosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
127	Small cell lung cancer 💬	1件: RARB 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
128	Sphingolipid signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
129	Systemic lupus erythematosus 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
130	Systemic lupus erythematosus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
131	T cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
132	T cell receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
133	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
134	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
135	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D00359 💬	Lovastatin	11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
136	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
137	TGF-beta signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
138	Th1 and Th2 cell differentiation 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
139	Th1 and Th2 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
140	Th17 cell differentiation 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
141	Th17 cell differentiation 💬	1件: IL4R 💬	D10354 💬	Dupilumab	4件: 51, 98, 160, 162 💬
142	Th17 cell differentiation 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
143	Th17 cell differentiation 💬	1件: RARA 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
144	TNF signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
145	Toll-like receptor signaling pathway 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
146	Toll-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
147	Toxoplasmosis 💬	1件: ALOX5 💬	D00414 💬	Zileuton	3件: 85, 160, 164 💬
148	Toxoplasmosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
149	Transcriptional misregulation in cancer 💬	1件: CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
150	Transcriptional misregulation in cancer 💬	1件: RARA 💬	D00348 💬	Isotretinoin	4件: 36, 39, 159, 160 💬
151	Tuberculosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
152	Tuberculosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
153	Type I diabetes mellitus 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
154	Type I diabetes mellitus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
155	Type II diabetes mellitus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
156	VEGF signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
157	Viral myocarditis 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
158	Viral protein interaction with cytokine and cytokine receptor 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
159	Wnt signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	1件: 160 💬
160	Yersinia infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬

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