DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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96 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: RARA 💬	D02754 💬	Acitretin	1件: 37 💬
2	Adipocytokine signaling pathway 💬	3件: RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
3	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
4	Adipocytokine signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
5	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
6	African trypanosomiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
7	African trypanosomiasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
8	African trypanosomiasis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
9	African trypanosomiasis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
11	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
12	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
13	Allograft rejection 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
14	Allograft rejection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
15	Allograft rejection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
16	Allograft rejection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
17	Alzheimer disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
18	Alzheimer disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
19	Alzheimer disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
20	Amoebiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
21	Amoebiasis 💬	2件: IL1R1, IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
22	Amoebiasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
23	Amoebiasis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
24	Amoebiasis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
25	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
26	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
27	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
28	Antifolate resistance 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
29	Antifolate resistance 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
30	Antifolate resistance 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
31	Antigen processing and presentation 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
32	Antigen processing and presentation 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
33	Antigen processing and presentation 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
34	Apoptosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
35	Apoptosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
36	Apoptosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
37	Asthma 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
38	Asthma 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
39	Asthma 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
40	Bile secretion 💬	1件: RXRA 💬	D02754 💬	Acitretin	1件: 37 💬
41	C-type lectin receptor signaling pathway 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
42	C-type lectin receptor signaling pathway 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
43	C-type lectin receptor signaling pathway 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
44	C-type lectin receptor signaling pathway 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
45	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
46	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
47	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
48	Cell adhesion molecules 💬	1件: CD58 💬	D02800 💬	Alefacept	6件: 37, 60, 65, 164, 284, 285 💬
49	Cell adhesion molecules 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
50	Chagas disease 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
51	Chagas disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
52	Chagas disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
53	Chagas disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
54	Coronavirus disease - COVID-19 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
55	Coronavirus disease - COVID-19 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
56	Coronavirus disease - COVID-19 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
57	Coronavirus disease - COVID-19 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
58	Cytokine-cytokine receptor interaction 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
59	Cytokine-cytokine receptor interaction 💬	1件: IL17A 💬	D10071 💬	Ixekizumab	5件: 36, 37, 162, 269, 271 💬
60	Cytokine-cytokine receptor interaction 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
61	Cytokine-cytokine receptor interaction 💬	1件: IL17RA 💬	D10061 💬	Brodalumab	2件: 37, 51 💬
62	Cytokine-cytokine receptor interaction 💬	2件: IL1R1, IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
63	Cytokine-cytokine receptor interaction 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
64	Cytokine-cytokine receptor interaction 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
65	Cytokine-cytokine receptor interaction 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
66	Cytokine-cytokine receptor interaction 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
67	Cytokine-cytokine receptor interaction 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
68	Cytokine-cytokine receptor interaction 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
69	Dilated cardiomyopathy 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
70	Dilated cardiomyopathy 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
71	Dilated cardiomyopathy 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
72	Drug metabolism - other enzymes 💬	1件: HPRT1 💬	D06109 💬	Tioguanine	2件: 13, 37 💬
73	Drug metabolism - other enzymes 💬	1件: HPRT1 💬	D08603 💬	Tioguanine	2件: 13, 37 💬
74	Endocrine and other factor-regulated calcium reabsorption 💬	1件: VDR 💬	D00129 💬	Calcitriol	8件: 37, 46, 49, 66, 96, 158, 235, 326 💬
75	Epstein-Barr virus infection 💬	1件: CD58 💬	D02800 💬	Alefacept	6件: 37, 60, 65, 164, 284, 285 💬
76	Epstein-Barr virus infection 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
77	Epstein-Barr virus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
78	Epstein-Barr virus infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
79	Epstein-Barr virus infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
80	Estrogen signaling pathway 💬	1件: RARA 💬	D02754 💬	Acitretin	1件: 37 💬
81	Fc epsilon RI signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
82	Fc epsilon RI signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
83	Fc epsilon RI signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
84	Fluid shear stress and atherosclerosis 💬	2件: IL1R1, IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
85	Fluid shear stress and atherosclerosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
86	Fluid shear stress and atherosclerosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
87	Fluid shear stress and atherosclerosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
88	Gastric cancer 💬	4件: RARB, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
89	Graft-versus-host disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
90	Graft-versus-host disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
91	Graft-versus-host disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
92	Hematopoietic cell lineage 💬	2件: IL1R1, IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
93	Hematopoietic cell lineage 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
94	Hematopoietic cell lineage 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
95	Hematopoietic cell lineage 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
96	Hepatitis B 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
97	Hepatitis B 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
98	Hepatitis B 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
99	Hepatitis C 💬	1件: RXRA 💬	D02754 💬	Acitretin	1件: 37 💬
100	Hepatitis C 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
101	Hepatitis C 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
102	Hepatitis C 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
103	Herpes simplex virus 1 infection 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
104	Herpes simplex virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
105	Herpes simplex virus 1 infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
106	Herpes simplex virus 1 infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
107	Human cytomegalovirus infection 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
108	Human cytomegalovirus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
109	Human cytomegalovirus infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
110	Human cytomegalovirus infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
111	Human immunodeficiency virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
112	Human immunodeficiency virus 1 infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
113	Human immunodeficiency virus 1 infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
114	Human papillomavirus infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
115	Human papillomavirus infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
116	Human papillomavirus infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
117	Human T-cell leukemia virus 1 infection 💬	2件: IL1R1, IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
118	Human T-cell leukemia virus 1 infection 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
119	Human T-cell leukemia virus 1 infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
120	Human T-cell leukemia virus 1 infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
121	Human T-cell leukemia virus 1 infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
122	Hypertrophic cardiomyopathy 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
123	Hypertrophic cardiomyopathy 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
124	Hypertrophic cardiomyopathy 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
125	IL-17 signaling pathway 💬	1件: IL17A 💬	D10071 💬	Ixekizumab	5件: 36, 37, 162, 269, 271 💬
126	IL-17 signaling pathway 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
127	IL-17 signaling pathway 💬	1件: IL17RA 💬	D10061 💬	Brodalumab	2件: 37, 51 💬
128	IL-17 signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
129	IL-17 signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
130	IL-17 signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
131	Inflammatory bowel disease 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
132	Inflammatory bowel disease 💬	1件: IL17A 💬	D10071 💬	Ixekizumab	5件: 36, 37, 162, 269, 271 💬
133	Inflammatory bowel disease 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
134	Inflammatory bowel disease 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
135	Inflammatory bowel disease 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
136	Inflammatory bowel disease 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
137	Inflammatory bowel disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
138	Inflammatory bowel disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
139	Inflammatory bowel disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
140	Inflammatory mediator regulation of TRP channels 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
141	Influenza A 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
142	Influenza A 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
143	Influenza A 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
144	Influenza A 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
145	Insulin resistance 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
146	Insulin resistance 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
147	Insulin resistance 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
148	JAK-STAT signaling pathway 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
149	JAK-STAT signaling pathway 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
150	JAK-STAT signaling pathway 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
151	JAK-STAT signaling pathway 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
152	Legionellosis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
153	Legionellosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
154	Legionellosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
155	Legionellosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
156	Leishmaniasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
157	Leishmaniasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
158	Leishmaniasis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
159	Leishmaniasis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
160	Leukocyte transendothelial migration 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
161	Malaria 💬	1件: IL12A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
162	Malaria 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
163	Malaria 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
164	Malaria 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
165	Malaria 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
166	MAPK signaling pathway 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
167	MAPK signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
168	MAPK signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
169	MAPK signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
170	Measles 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
171	Metabolic pathways 💬	1件: HPRT1 💬	D06109 💬	Tioguanine	2件: 13, 37 💬
172	Metabolic pathways 💬	1件: HPRT1 💬	D08603 💬	Tioguanine	2件: 13, 37 💬
173	Mineral absorption 💬	1件: VDR 💬	D00129 💬	Calcitriol	8件: 37, 46, 49, 66, 96, 158, 235, 326 💬
174	mTOR signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
175	mTOR signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
176	mTOR signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
177	Natural killer cell mediated cytotoxicity 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
178	Natural killer cell mediated cytotoxicity 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
179	Natural killer cell mediated cytotoxicity 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
180	Natural killer cell mediated cytotoxicity 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
181	Necroptosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
182	Necroptosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
183	Necroptosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
184	Neutrophil extracellular trap formation 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
185	NF-kappa B signaling pathway 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
186	NF-kappa B signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
187	NF-kappa B signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
188	NF-kappa B signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
189	NOD-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
190	NOD-like receptor signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
191	NOD-like receptor signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
192	Non-alcoholic fatty liver disease 💬	1件: RXRA 💬	D02754 💬	Acitretin	1件: 37 💬
193	Non-alcoholic fatty liver disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
194	Non-alcoholic fatty liver disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
195	Non-alcoholic fatty liver disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
196	Non-small cell lung cancer 💬	4件: RARB, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
197	Osteoclast differentiation 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
198	Osteoclast differentiation 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
199	Osteoclast differentiation 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
200	Osteoclast differentiation 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
201	Parathyroid hormone synthesis, secretion and action 💬	3件: RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
202	Parathyroid hormone synthesis, secretion and action 💬	1件: VDR 💬	D00129 💬	Calcitriol	8件: 37, 46, 49, 66, 96, 158, 235, 326 💬
203	Pathogenic Escherichia coli infection 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
204	Pathogenic Escherichia coli infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
205	Pathogenic Escherichia coli infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
206	Pathogenic Escherichia coli infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
207	Pathways in cancer 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
208	Pathways in cancer 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
209	Pathways in cancer 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
210	Pathways in cancer 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
211	Pathways in cancer 💬	5件: RARA, RARB, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
212	Pathways of neurodegeneration - multiple diseases 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
213	Pathways of neurodegeneration - multiple diseases 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
214	Pathways of neurodegeneration - multiple diseases 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
215	Pertussis 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
216	Pertussis 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
217	Pertussis 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
218	Pertussis 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
219	Pertussis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
220	Pertussis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
221	Pertussis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
222	PI3K-Akt signaling pathway 💬	1件: RXRA 💬	D02754 💬	Acitretin	1件: 37 💬
223	PPAR signaling pathway 💬	3件: RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
224	Prion disease 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
225	Prion disease 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
226	Prion disease 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
227	Prostate cancer 💬	1件: IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
228	Proteoglycans in cancer 💬	1件: IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
229	Proteoglycans in cancer 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
230	Proteoglycans in cancer 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
231	Proteoglycans in cancer 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
232	Purine metabolism 💬	1件: HPRT1 💬	D06109 💬	Tioguanine	2件: 13, 37 💬
233	Purine metabolism 💬	1件: HPRT1 💬	D08603 💬	Tioguanine	2件: 13, 37 💬
234	Rap1 signaling pathway 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
235	Regulation of actin cytoskeleton 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
236	Rheumatoid arthritis 💬	1件: IL17A 💬	D10071 💬	Ixekizumab	5件: 36, 37, 162, 269, 271 💬
237	Rheumatoid arthritis 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
238	Rheumatoid arthritis 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
239	Rheumatoid arthritis 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
240	Rheumatoid arthritis 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
241	Rheumatoid arthritis 💬	1件: IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
242	Rheumatoid arthritis 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
243	Rheumatoid arthritis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
244	Rheumatoid arthritis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
245	Rheumatoid arthritis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
246	RIG-I-like receptor signaling pathway 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
247	RIG-I-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
248	RIG-I-like receptor signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
249	RIG-I-like receptor signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
250	Salmonella infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
251	Salmonella infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
252	Salmonella infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
253	Shigellosis 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
254	Shigellosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
255	Shigellosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
256	Shigellosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
257	Small cell lung cancer 💬	4件: RARB, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
258	Sphingolipid signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
259	Sphingolipid signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
260	Sphingolipid signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
261	Staphylococcus aureus infection 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
262	Systemic lupus erythematosus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
263	Systemic lupus erythematosus 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
264	Systemic lupus erythematosus 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
265	T cell receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
266	T cell receptor signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
267	T cell receptor signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
268	TGF-beta signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
269	TGF-beta signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
270	TGF-beta signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
271	Th1 and Th2 cell differentiation 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
272	Th17 cell differentiation 💬	1件: IL17A 💬	D10071 💬	Ixekizumab	5件: 36, 37, 162, 269, 271 💬
273	Th17 cell differentiation 💬	1件: IL17A 💬	D09967 💬	Secukinumab	7件: 13, 37, 41, 46, 160, 269, 271 💬
274	Th17 cell differentiation 💬	1件: IL1R1 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
275	Th17 cell differentiation 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
276	Th17 cell differentiation 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
277	Th17 cell differentiation 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
278	Th17 cell differentiation 💬	1件: IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
279	Th17 cell differentiation 💬	4件: RARA, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
280	Thyroid cancer 💬	3件: RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
281	Thyroid hormone signaling pathway 💬	3件: RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
282	TNF signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
283	TNF signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
284	TNF signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
285	Toll-like receptor signaling pathway 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
286	Toll-like receptor signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
287	Toll-like receptor signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
288	Toll-like receptor signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
289	Toxoplasmosis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
290	Toxoplasmosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
291	Toxoplasmosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
292	Toxoplasmosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
293	Transcriptional misregulation in cancer 💬	1件: IL1R2 💬	D02934 💬	Anakinra	19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
294	Transcriptional misregulation in cancer 💬	4件: RARA, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	1件: 37 💬
295	Tuberculosis 💬	3件: IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
296	Tuberculosis 💬	1件: IL23A 💬	D10438 💬	Guselkumab	4件: 37, 41, 96, 97 💬
297	Tuberculosis 💬	1件: IL23A 💬	D11123 💬	Mirikizumab	3件: 37, 96, 97 💬
298	Tuberculosis 💬	1件: IL23A 💬	D11052 💬	Risankizumab	4件: 37, 96, 97, 271 💬
299	Tuberculosis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
300	Tuberculosis 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
301	Tuberculosis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
302	Tuberculosis 💬	1件: VDR 💬	D00129 💬	Calcitriol	8件: 37, 46, 49, 66, 96, 158, 235, 326 💬
303	Type I diabetes mellitus 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
304	Type I diabetes mellitus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
305	Type I diabetes mellitus 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
306	Type I diabetes mellitus 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
307	Type II diabetes mellitus 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
308	Type II diabetes mellitus 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
309	Type II diabetes mellitus 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
310	Viral myocarditis 💬	1件: ITGAL 💬	D03959 💬	Efalizumab	9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
311	Viral protein interaction with cytokine and cytokine receptor 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
312	Viral protein interaction with cytokine and cytokine receptor 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
313	Viral protein interaction with cytokine and cytokine receptor 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
314	Yersinia infection 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
315	Yersinia infection 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
316	Yersinia infection 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬

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