Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10001 Fingolimod 3件: 13, 14, 156
2 FCGRT - D11666 Nipocalimab 5件: 14, 46, 49, 53, 61
3 FCGRT - D11876 Efgartigimod alfa 5件: 14, 35, 53, 63, 162
4 FCGRT - D11983 Batoclimab 1件: 14
5 FCGRT - D12182 Rozanolixizumab 2件: 14, 63
6 NR3C1 1件: Neuroactive ligand-receptor interaction D00292 Dexamethasone 21件: 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
7 NR3C1 1件: Neuroactive ligand-receptor interaction D00407 Methylprednisolone 43件: 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
8 NR3C1 1件: Neuroactive ligand-receptor interaction D00472 Prednisolone 39件: 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
9 NR3C1 1件: Neuroactive ligand-receptor interaction D00473 Prednisone 42件: 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
10 HRH1 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D07398 Chlorpheniramine 1件: 14
11 KCNA4 2件: Cortisol synthesis and secretion, Cushing syndrome D04127 Dalfampridine 5件: 3, 4, 6, 13, 14
12 KCNC3 1件: Spinocerebellar ataxia D04127 Dalfampridine 1件: 14
13 KCND2 1件: Serotonergic synapse D04127 Dalfampridine 1件: 14
14 KCND3 1件: Spinocerebellar ataxia D04127 Dalfampridine 1件: 14
15 MC2R 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome D00146 Corticotropin 12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
16 TOP2A 1件: Platinum drug resistance D00125 Etoposide 9件: 14, 26, 28, 34, 60, 65, 85, 164, 331
17 TOP2B 1件: Platinum drug resistance D00125 Etoposide 9件: 14, 26, 28, 34, 60, 65, 85, 164, 331
18 C5 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
19 MS4A1 1件: Hematopoietic cell lineage D02994 Rituximab 46件: 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331