Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CSF3R 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer D03235 Filgrastim 35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
2 ADRA1D 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D00076 Norepinephrine 2件: 22, 296
3 ADRA1D 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D08365 Phenylephrine 1件: 22
4 ADRA1B 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D00076 Norepinephrine 2件: 22, 296
5 ADRA1B 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D08365 Phenylephrine 1件: 22
6 ADRA1A 7件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D00076 Norepinephrine 2件: 22, 296
7 ADRA1A 7件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion D08365 Phenylephrine 1件: 22
8 ADRA2A 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00076 Norepinephrine 2件: 22, 296
9 ADRA2B 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00076 Norepinephrine 2件: 22, 296
10 ADRA2C 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00076 Norepinephrine 2件: 22, 296
11 ADRB1 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy D00076 Norepinephrine 2件: 22, 296
12 ADRB2 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D00076 Norepinephrine 2件: 22, 296
13 ADRB3 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D00076 Norepinephrine 2件: 22, 296
14 GABRA1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
15 GABRA2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
16 GABRA3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
17 GABRA4 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
18 GABRA5 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
19 GABRA6 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
20 GABRB1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
21 GABRB2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
22 GABRB3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
23 GABRD 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
24 GABRE 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
25 GABRG1 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
26 GABRG2 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
27 GABRG3 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
28 GABRP 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
29 GABRQ 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
30 PTGS1 5件: Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
31 PTGS2 22件: Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
32 SCN1A 1件: Dopaminergic synapse D00358 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
33 SCN1A 1件: Dopaminergic synapse D08127 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
34 SCN1A 1件: Dopaminergic synapse D08490 Ropivacaine 4件: 22, 36, 46, 70
35 SCN2A 1件: Taste transduction D00358 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
36 SCN2A 1件: Taste transduction D08127 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
37 SCN2A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
38 SCN3A 1件: Taste transduction D00358 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
39 SCN3A 1件: Taste transduction D08127 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
40 SCN3A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
41 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00358 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
42 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08127 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
43 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08490 Ropivacaine 4件: 22, 36, 46, 70
44 SCN9A 1件: Taste transduction D00358 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
45 SCN9A 1件: Taste transduction D08127 Lidocaine 11件: 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
46 SCN9A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70