Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 F8 1件: Complement and coagulation cascades D00291 Desmopressin 4件: 72, 75, 225, 288
2 GLP1R 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion D04121 Exenatide 6件: 6, 17, 72, 78, 193, 233
3 MTNR1A 2件: Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin 12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
4 MTNR1B 2件: Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin 12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
5 OXTR 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway D00089 Oxytocin 7件: 6, 72, 127, 168, 193, 206, 226
6 AVPR2 3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption D00291 Desmopressin 6件: 6, 64, 72, 75, 225, 288
7 AVPR2 3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption D01213 Tolvaptan 4件: 67, 72, 86, 225
8 SLC5A2 - D10459 Empagliflozin 3件: 72, 97, 257