Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ESR1 9件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
2 ESR2 7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
3 NR3C1 1件: Neuroactive ligand-receptor interaction D00088 Hydrocortisone 3件: 83, 97, 299
4 NR3C1 1件: Neuroactive ligand-receptor interaction D00244 Betamethasone 4件: 83, 90, 96, 235
5 NR3C1 1件: Neuroactive ligand-receptor interaction D00407 Methylprednisolone 20件: 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
6 NR3C1 1件: Neuroactive ligand-receptor interaction D00976 Hydrocortisone cypionate 1件: 83
7 NR3C1 1件: Neuroactive ligand-receptor interaction D01442 Hydrocortisone succinate 1件: 83
8 AR 4件: Oocyte meiosis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
9 MC2R 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome D00284 Tetracosactide 5件: 78, 83, 113, 145, 222
10 MS4A1 1件: Hematopoietic cell lineage D02994 Rituximab 21件: 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331