Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 2 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 3 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
| 4 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 3件: 79, 218, 222 💬 |
| 5 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 6 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 7 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 8 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
| 9 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
| 10 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 3件: 79, 218, 222 💬 |
| 11 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 12 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 13 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 14 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
| 15 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 16 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 17 | Cholesterol metabolism 💬 Related to 6 target genes, 8 drugs (DrugBank) and 6 diseases in DDrare |
ANGPTL3 1件: ANGPTL3 💬 |
D11753 D11753 💬 |
Evinacumab | 079 1件: 79 💬 |
| 18 | Cholesterol metabolism 💬 Related to 6 target genes, 8 drugs (DrugBank) and 6 diseases in DDrare |
CETP 1件: CETP 💬 |
D08855 D08855 💬 |
Anacetrapib | 079 1件: 79 💬 |
| 19 | Cholesterol metabolism 💬 Related to 6 target genes, 8 drugs (DrugBank) and 6 diseases in DDrare |
PCSK9 1件: PCSK9 💬 |
D10335 D10335 💬 |
Alirocumab | 079 1件: 79 💬 |
| 20 | Cholesterol metabolism 💬 Related to 6 target genes, 8 drugs (DrugBank) and 6 diseases in DDrare |
PCSK9 1件: PCSK9 💬 |
D10557 D10557 💬 |
Evolocumab | 079 2件: 79, 222 💬 |
| 21 | Cholesterol metabolism 💬 Related to 6 target genes, 8 drugs (DrugBank) and 6 diseases in DDrare |
PCSK9 1件: PCSK9 💬 |
D11931 D11931 💬 |
Inclisiran | 079 1件: 79 💬 |
| 22 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 23 | Fat digestion and absorption 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
MTTP 1件: MTTP 💬 |
D09637 D09637 💬 |
Lomitapide | 079 1件: 79 💬 |
| 24 | Fat digestion and absorption 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
NPC1L1 1件: NPC1L1 💬 |
D01966 D01966 💬 |
Ezetimibe | 049 4件: 49, 79, 93, 260 💬 |
| 25 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 26 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 27 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 28 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
| 29 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 3件: 79, 218, 222 💬 |
| 30 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 31 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 32 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 33 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
| 34 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
| 35 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 36 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 |
| 37 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
| 38 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 3件: 79, 218, 222 💬 |
| 39 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 40 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 41 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 42 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |