DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）

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11 / 275 pathways found* Show info (disease name, etc.) on mouse-over.

No.	KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related	KEGG GENES *	KEGG DRUG *	DrugBank	指定難病告示番号 *
1	Adrenergic signaling in cardiomyocytes 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
2	Calcium signaling pathway 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
3	cAMP signaling pathway 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
4	cGMP-PKG signaling pathway 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
5	Cortisol synthesis and secretion 1 gene, 1 drug (DrugBank) and 3 diseases shown	1件: KCNA4	D10228	Amifampridine	3件: 3, 11, 12
6	Cushing syndrome 1 gene, 1 drug (DrugBank) and 3 diseases shown	1件: KCNA4	D10228	Amifampridine	3件: 3, 11, 12
7	Neuroactive ligand-receptor interaction 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
8	Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
9	Renin secretion 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
10	Salivary secretion 1 gene, 1 drug (DrugBank) and 13 diseases shown	1件: ADRB2	D02147	Salbutamol	13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
11	Serotonergic synapse 1 gene, 1 drug (DrugBank) and 3 diseases shown	1件: KCND2	D10228	Amifampridine	3件: 3, 11, 12