↑ トップへ　← 戻る

 Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト） 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"

A　B　C　D　E　F　G　H　 I 　J　K　L　M　N　O　P　Q　R　S　T　U　V　W　X　Y　Z　other

101 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES *   KEGG DRUG *   DrugBank   指定難病告示番号 * 
 1  Adipocytokine signaling pathway 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 2  African trypanosomiasis 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 3  AGE-RAGE signaling pathway in diabetic complications 
 2 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 4  Allograft rejection 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 5  Alzheimer disease 
 7 genes, 6 drugs (DrugBank) and 60 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 6  Amoebiasis 
 6 genes, 7 drugs (DrugBank) and 45 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 7  Amphetamine addiction 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 8  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 4 drugs (DrugBank) and 56 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 9  Antifolate resistance 
 4 genes, 6 drugs (DrugBank) and 54 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 10  Antigen processing and presentation 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 11  Apoptosis 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 12  Asthma 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 13  Axon guidance 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 14  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 15  C-type lectin receptor signaling pathway 
 10 genes, 7 drugs (DrugBank) and 62 diseases shown 		  3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 16  Calcium signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 17  cAMP signaling pathway 
 4 genes, 1 drug (DrugBank) and 5 diseases shown 		  4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 18  Cellular senescence 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 19  cGMP-PKG signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 20  Chagas disease (American trypanosomiasis) 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 21  Cytokine-cytokine receptor interaction 
 11 genes, 9 drugs (DrugBank) and 49 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 22  Cytosolic DNA-sensing pathway 
 1 gene, 2 drugs (DrugBank) and 11 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 23  Dilated cardiomyopathy (DCM) 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 24  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank) and 44 diseases shown 		  3件: PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 25  Endocytosis 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 		  1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 26  Epstein-Barr virus infection 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 27  Fc epsilon RI signaling pathway 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 28  Fluid shear stress and atherosclerosis 
 4 genes, 6 drugs (DrugBank) and 44 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 29  Folate biosynthesis 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 30  Gap junction 
 9 genes, 1 drug (DrugBank) and 5 diseases shown 		  9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   5件: 2, 42, 56, 93, 266 
 31  Glucagon signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 32  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 33  Graft-versus-host disease 
 2 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 34  Hematopoietic cell lineage 
 6 genes, 8 drugs (DrugBank) and 66 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 35  Hepatitis B 
 2 genes, 4 drugs (DrugBank) and 37 diseases shown 		  1件: IFNAR1   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 36  Hepatitis C 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 37  Herpes simplex virus 1 infection 
 7 genes, 7 drugs (DrugBank) and 44 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 38  Human cytomegalovirus infection 
 8 genes, 7 drugs (DrugBank) and 64 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 39  Human immunodeficiency virus 1 infection 
 6 genes, 4 drugs (DrugBank) and 56 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 40  Human papillomavirus infection 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 41  Human T-cell leukemia virus 1 infection 
 10 genes, 6 drugs (DrugBank) and 63 diseases shown 		  2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 42  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 43  IL-17 signaling pathway 
 2 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 44  Inflammatory bowel disease (IBD) 
 5 genes, 6 drugs (DrugBank) and 42 diseases shown 		  3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 45  Inflammatory mediator regulation of TRP channels 
 2 genes, 3 drugs (DrugBank) and 20 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 46  Influenza A 
 6 genes, 7 drugs (DrugBank) and 44 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 47  Insulin resistance 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 48  JAK-STAT signaling pathway 
 6 genes, 3 drugs (DrugBank) and 22 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 49  Kaposi sarcoma-associated herpesvirus infection 
 7 genes, 2 drugs (DrugBank) and 46 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 50  Legionellosis 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 51  Leishmaniasis 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 52  Long-term potentiation 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 53  Malaria 
 3 genes, 6 drugs (DrugBank) and 42 diseases shown 		  1件: IL12A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 54  MAPK signaling pathway 
 8 genes, 7 drugs (DrugBank) and 64 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 55  Measles 
 6 genes, 5 drugs (DrugBank) and 27 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 56  Metabolic pathways 
 6 genes, 2 drugs (DrugBank) and 33 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 57  Morphine addiction 
 4 genes, 1 drug (DrugBank) and 5 diseases shown 		  4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 58  mTOR signaling pathway 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 59  Natural killer cell mediated cytotoxicity 
 8 genes, 5 drugs (DrugBank) and 57 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 60  Necroptosis 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 61  Neuroactive ligand-receptor interaction 
 1 gene, 2 drugs (DrugBank) and 46 diseases shown 		  1件: NR3C1   D00472   Prednisolone   38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 D00385   Triamcinolone   18件: 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 
 D00983 
 D00984 
 D00985 
 D06216 
 62  NF-kappa B signaling pathway 
 4 genes, 6 drugs (DrugBank) and 44 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 63  NOD-like receptor signaling pathway 
 4 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 64  Non-alcoholic fatty liver disease (NAFLD) 
 2 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 65  One carbon pool by folate 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 66  Oocyte meiosis 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 67  Osteoclast differentiation 
 10 genes, 8 drugs (DrugBank) and 65 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 68  Oxytocin signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 69  Parathyroid hormone synthesis, secretion and action 
 4 genes, 1 drug (DrugBank) and 5 diseases shown 		  4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 70  Pathogenic Escherichia coli infection 
 12 genes, 7 drugs (DrugBank) and 46 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   5件: 2, 42, 56, 93, 266 
 71  Pathways in cancer 
 6 genes, 3 drugs (DrugBank) and 22 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 72  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 73  Pertussis 
 5 genes, 6 drugs (DrugBank) and 42 diseases shown 		  3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 74  Phagosome 
 9 genes, 1 drug (DrugBank) and 5 diseases shown 		  9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   5件: 2, 42, 56, 93, 266 
 75  PI3K-Akt signaling pathway 
 3 genes, 2 drugs (DrugBank) and 11 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 76  Prion diseases 
 1 gene, 2 drugs (DrugBank) and 11 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 77  Prostate cancer 
 1 gene, 1 drug (DrugBank) and 17 diseases shown 		  1件: IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 78  Proteoglycans in cancer 
 2 genes, 4 drugs (DrugBank) and 37 diseases shown 		  1件: IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 79  Purine metabolism 
 4 genes, 1 drug (DrugBank) and 5 diseases shown 		  4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 80  Renin secretion 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 81  Rheumatoid arthritis 
 3 genes, 6 drugs (DrugBank) and 42 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 82  RIG-I-like receptor signaling pathway 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 83  Salmonella infection 
 1 gene, 2 drugs (DrugBank) and 11 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 84  Shigellosis 
 3 genes, 6 drugs (DrugBank) and 44 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 85  Sphingolipid signaling pathway 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 86  Systemic lupus erythematosus 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 87  T cell receptor signaling pathway 
 6 genes, 4 drugs (DrugBank) and 56 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 88  TGF-beta signaling pathway 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 89  Th1 and Th2 cell differentiation 
 8 genes, 3 drugs (DrugBank) and 50 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 90  Th17 cell differentiation 
 9 genes, 6 drugs (DrugBank) and 58 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 91  TNF signaling pathway 
 3 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 92  Toll-like receptor signaling pathway 
 6 genes, 7 drugs (DrugBank) and 44 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 93  Toxoplasmosis 
 3 genes, 4 drugs (DrugBank) and 37 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 94  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank) and 17 diseases shown 		  1件: IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 95  Tuberculosis 
 10 genes, 7 drugs (DrugBank) and 62 diseases shown 		  3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 96  Type I diabetes mellitus 
 5 genes, 6 drugs (DrugBank) and 42 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 97  Type II diabetes mellitus 
 1 gene, 3 drugs (DrugBank) and 35 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 98  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 99  Viral protein interaction with cytokine and cytokine receptor 
 3 genes, 4 drugs (DrugBank) and 38 diseases shown 		  1件: IL2RA   D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 100  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 101  Yersinia infection 
 2 genes, 5 drugs (DrugBank) and 40 diseases shown 		  1件: IL1B   D09315   Canakinumab   9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 
 D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 

先頭へ