Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ACOMPLIA 20 mg film-coated tablets1件: Rimonabant1件: Rimonabant 💬1件: CNR1 💬4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193 💬
2Actonel Once a Week 35 mg film-coated tablets1件: Risedronic acid1件: Risedronic acid 💬1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274 💬
3Actonel/Optinate 5mg film-coated tablets1件: Risedronic acid1件: Risedronic acid 💬1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274 💬
4ADCIRCA 20 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
5Adempas® 0.5 mg film-coated tablets1件: Riociguat1件: Riociguat 💬3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 86 💬
6Adempas® 1.0 mg film-coated tablets1件: Riociguat1件: Riociguat 💬3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 86 💬
7Adempas® 1.5 mg film-coated tablets1件: Riociguat1件: Riociguat 💬3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 86 💬
8Adempas® 2.0 mg film-coated tablets1件: Riociguat1件: Riociguat 💬3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 86 💬
9Adempas® 2.5 mg film-coated tablets1件: Riociguat1件: Riociguat 💬3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 86 💬
10Ambrisentan 5 mg film-coated tablets1件: Ambrisentan1件: Ambrisentan 💬1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
11Ambrisentan 5mg film-coated tablets [marketed product]1件: Ambrisentan1件: Ambrisentan 💬1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
12Aubagio 14 mg film-coated tablets1件: Teriflunomide1件: Teriflunomide 💬1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬1件: 13 💬
13Azithromycin 500 mg film-coated tablet1件: Azithromycin2件: Azithromycin ,
Azithromycin 💬		--1件: 299 💬
14CellCept 500 mg film-coated tablets1件: Mycophenolate mofetil1件: Mycophenolate mofetil 💬2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬1件: 11 💬
15Cialis 10 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 113 💬
16Cialis 2.5 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 113 💬
17Cialis 20 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 113 💬
18Cialis 5 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 113 💬
19Crestor Film-Coated Tablet1件: Rosuvastatin1件: Rosuvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 79 💬
20Crestor Tablets (calcium rosuvastatin) Film-Coated tablets2件: Calcium,
Rosuvastatin		1件: Rosuvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 79 💬
21Cuprior 150 mg film-coated tablets1件: Triethylenetetramine---1件: 171 💬
22Cuprior 150mg film-coated tablets1件: Triethylenetetramine---1件: 171 💬
23Doptelet 20 mg film-coated tablets1件: Avatrombopag1件: Avatrombopag 💬1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 63 💬
24Film-coated tablet----1件: 97 💬
25Fostamatinib 50 mg blue film-coated tablet1件: Fostamatinib1件: Fostamatinib 💬1件: SYK 💬17件: B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
26Glentek 50 mg film-coated tablets----1件: 18 💬
27GLPG3970 film-coated tablet----1件: 49 💬
28Idebenone 150 mg film-coated tablets1件: Idebenone1件: Idebenone 💬--1件: 113 💬
29JNJ-38518168-ZBQ - film-coated tablet - 10 mg----1件: 46 💬
30JNJ-38518168-ZBQ - film-coated tablet - 10mg----1件: 46 💬
31JNJ-38518168-ZBQ - film-coated tablet - 3 mg----1件: 46 💬
32JNJ-38518168-ZBQ - film-coated tablet - 30 mg----1件: 46 💬
33JNJ-38518168-ZBQ - film-coated tablet - 30mg----1件: 46 💬
34JNJ-38518168-ZBQ - film-coated tablet - 3mg----1件: 46 💬
35Jyseleca 100 mg film-coated tablets1件: Filgotinib1件: Filgotinib 💬1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
36Jyseleca 200 mg film-coated tablets1件: Filgotinib1件: Filgotinib 💬1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46 💬
37Kalydeco 150 mg film-coated tablets1件: Ivacaftor1件: Ivacaftor 💬1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Mayzent 2 mg film-coated tablets1件: Siponimod1件: Siponimod 💬2件: S1PR1,
S1PR5 💬		3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 13 💬
39Minocycline 100 mg Film-coated Tablets1件: Minocycline1件: Minocycline 💬--1件: 13 💬
40Norvir 100 mg film-coated tablets----1件: 299 💬
41Ondansetron 8 mg film-coated tablets1件: Ondansetron1件: Ondansetron 💬5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬1件: 6 💬
42Orkambi 100 mg/125 mg film-coated tablets2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor ,
Lumacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
43Orkambi 200 mg/125 mg film-coated tablets2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor ,
Lumacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
44Revatio 20 mg film-coated tablets----1件: 86 💬
45Revatio ® 20 mg film-coated tablets1件: Sildenafil1件: Sildenafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
46Revolade 25 mg film-coated tablets1件: Eltrombopag---1件: 63 💬
47Revolade 50 mg film-coated tablets1件: Eltrombopag---1件: 63 💬
48Rilutek 50 mg film-coated tablets1件: Riluzole1件: Riluzole 💬14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬1件: 2 💬
49RILUTEK 50 mg, film-coated tablets1件: Riluzole1件: Riluzole 💬14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬1件: 2 💬
50Simvastatin 40 mg film-coated tablets1件: Simvastatin1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 13 💬
51Sivatin 40 mg film-coated tablets----1件: 13 💬
52Symkevi 100mg/150mg Film-coated tablets2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
53Tadalafil 20 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
54Ursofalk® 500 mg film-coated tablets1件: Ursodeoxycholic acid1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬1件: 93 💬
55XELJANZ 5 mg film-coated tablets1件: Tofacitinib1件: Tofacitinib 💬4件: JAK1,
JAK2,
JAK3,
TYK2 💬		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬2件: 46, 97 💬
56Xeljanz 5mg film-coated tablets1件: Tofacitinib1件: Tofacitinib 💬4件: JAK1,
JAK2,
JAK3,
TYK2 💬		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 97 💬