Drug Description in Trials / DrugBank / KEGG DRUG


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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1Dopamine Agonists (pramipexole, ropirinole)2件: Dopamine,
Pramipexole
4件: D00559 (Name: Pramipexole dihydrochloride),
D00633 ,
D05575 (Name: Pramipexole),
D07870
5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
2Mirapex (pramipexole)1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
3P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),2件: Pramipexole,
Rasagiline
5件: D00559 (Name: Pramipexole dihydrochloride),
D02562 ,
D05575 (Name: Pramipexole),
D08469 ,
D10829
4件: DRD2,
DRD3,
DRD4,
MAOB 💬
18件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6
4P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),2件: Pramipexole,
Rasagiline
5件: D00559 (Name: Pramipexole dihydrochloride),
D02562 ,
D05575 (Name: Pramipexole),
D08469 ,
D10829
4件: DRD2,
DRD3,
DRD4,
MAOB 💬
18件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6
5Pramipexole1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
6Pramipexole 0.125 mg tablets1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
7Pramipexole 0.5 mg tablets1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
8PRAMIPEXOLE DIHYDROCHLORIDE1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
9Pramipexole dihydrochloride extended-release tablets1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
10PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
11Pramipexole dihydrochloride monohydrate extended release2件: Manganese citrate,
Pramipexole
2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
12Pramipexole ER1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
13Pramipexole Extended Release1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
14Pramipexole extended release tablet1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
15Pramipexole hydrochloride sustained-release tablet (Siforl®) Specification: 0.26mg/ tablet (in pramipexole)1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
16Pramipexole Immediate Release1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
17Pramipexole immediate release tablet1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
18Pramipexole IR1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
19Pramipexole or ropinirole2件: Pramipexole,
Ropinirole
4件: D00559 (Name: Pramipexole dihydrochloride),
D00784 ,
D05575 (Name: Pramipexole),
D08489
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
20Pramipexole SR1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
21Praxol hydrochloride sustained release tablet Specification: 0.375mg/ tablet (in pramipexole hydrochloride)1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
22R(+) pramipexole dihydrochloride monohydrate1件: Pramipexole2件: D00559 (Name: Pramipexole dihydrochloride),
D05575 (Name: Pramipexole)
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 2