Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ODC1 💬 3件: Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways Eflornithine 💬 Eflornithine 1件: 65 💬
2 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Nalmefene 💬 Nalmefene 1件: 6 💬
3 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
4 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Oxycodone 💬 Oxycodone 5件: 6, 13, 70, 226, 298 💬
5 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Loperamide 💬 Loperamide 2件: 13, 97 💬
6 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Nalbuphine 💬 Nalbuphine 1件: 85 💬
7 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Naloxone 💬 Naloxone 2件: 6, 226 💬
8 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Dezocine 💬 Dezocine 1件: 46 💬
9 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Nalmefene 💬 Nalmefene 1件: 6 💬
10 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
11 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Oxycodone 💬 Oxycodone 5件: 6, 13, 70, 226, 298 💬
12 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Buprenorphine 💬 Buprenorphine 2件: 46, 70 💬
13 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Loperamide 💬 Loperamide 2件: 13, 97 💬
14 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Nalbuphine 💬 Nalbuphine 1件: 85 💬
15 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Naloxone 💬 Naloxone 2件: 6, 226 💬
16 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Trimebutine 💬 Trimebutine 1件: 51 💬
17 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Fentanyl 💬 Fentanyl 3件: 46, 70, 215 💬
18 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Dezocine 💬 Dezocine 1件: 46 💬
19 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Nalmefene 💬 Nalmefene 1件: 6 💬
20 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
21 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Oxycodone 💬 Oxycodone 5件: 6, 13, 70, 226, 298 💬
22 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Sufentanil 💬 Sufentanil 2件: 70, 280 💬
23 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Buprenorphine 💬 Buprenorphine 2件: 46, 70 💬
24 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Dihydrocodeine 💬 Dihydrocodeine 1件: 310 💬
25 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Hydromorphone 💬 Hydromorphone 1件: 70 💬
26 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Loperamide 💬 Loperamide 2件: 13, 97 💬
27 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Morphine 💬 Morphine 5件: 36, 46, 70, 85, 86 💬
28 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Nalbuphine 💬 Nalbuphine 1件: 85 💬
29 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Naloxone 💬 Naloxone 2件: 6, 226 💬
30 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Oxymorphone 💬 Oxymorphone 1件: 70 💬
31 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Remifentanil 💬 Remifentanil 2件: 6, 70 💬
32 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Tramadol 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
33 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Trimebutine 💬 Trimebutine 1件: 51 💬
34 OXTR 💬 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway Oxytocin 💬 Oxytocin 7件: 6, 72, 127, 168, 193, 206, 226 💬
35 OXTR 💬 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway Atosiban 💬 Atosiban 1件: 118 💬