Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan 💬 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
2 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
3 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine 1件: 156 💬
4 SLC22A12 💬 - Benzbromarone 💬 Benzbromarone 1件: 86 💬
5 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
6 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod 1件: 97 💬
7 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
8 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
9 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ponesimod 💬 Ponesimod 1件: 13 💬
10 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Cenerimod 💬 Cenerimod 1件: 49 💬
11 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Siponimod 💬 Siponimod 2件: 13, 50 💬
12 S1PR3 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod 1件: 97 💬
13 S1PR3 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
14 S1PR3 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
15 SV2C 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬
16 SIGLEC8 💬 - Lirentelimab 💬 Lirentelimab 1件: 98 💬
17 SERPIND1 💬 1件: Complement and coagulation cascades Sulodexide 💬 Sulodexide 2件: 51, 271 💬
18 SMAD7 💬 2件: TGF-beta signaling pathway, Hippo signaling pathway Mongersen 💬 Mongersen 2件: 96, 97 💬
19 SERPINC1 💬 1件: Complement and coagulation cascades Adomiparin 💬 Heparin 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
20 SERPINC1 💬 1件: Complement and coagulation cascades Adomiparin 💬 Enoxaparin 1件: 46 💬
21 SERPINC1 💬 1件: Complement and coagulation cascades Adomiparin 💬 Parnaparin 1件: 97 💬
22 SERPINC1 💬 1件: Complement and coagulation cascades Sulodexide 💬 Sulodexide 2件: 51, 271 💬
23 SOST 💬 2件: Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action Romosozumab 💬 Romosozumab 1件: 274 💬
24 S1PR5 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod 1件: 97 💬
25 S1PR5 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
26 S1PR5 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
27 S1PR5 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Siponimod 💬 Siponimod 2件: 13, 50 💬
28 SLAMF7 💬 - Elotuzumab 💬 Elotuzumab 1件: 28 💬
29 SORT1 💬 3件: Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab 2件: 2, 127 💬
30 SCN1A 💬 1件: Dopaminergic synapse Carbamazepine 💬 Carbamazepine 3件: 6, 13, 231 💬
31 SCN1A 💬 1件: Dopaminergic synapse Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
32 SCN1A 💬 1件: Dopaminergic synapse Lidocaine 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
33 SCN1A 💬 1件: Dopaminergic synapse Phenytoin 💬 Phenytoin 1件: 13 💬
34 SCN1A 💬 1件: Dopaminergic synapse Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
35 SCN1A 💬 1件: Dopaminergic synapse Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
36 SCN1A 💬 1件: Dopaminergic synapse Zonisamide 💬 Zonisamide 1件: 6 💬
37 SCN1A 💬 1件: Dopaminergic synapse Amiodarone 💬 Amiodarone 2件: 28, 127 💬
38 SCN1A 💬 1件: Dopaminergic synapse Cifenline 💬 Cibenzoline 1件: 58 💬
39 SCN1A 💬 1件: Dopaminergic synapse Rufinamide 💬 Rufinamide 1件: 144 💬
40 SCN1A 💬 1件: Dopaminergic synapse Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
41 SCN1A 💬 1件: Dopaminergic synapse Flecainide 💬 Flecainide 1件: 6 💬
42 SCN1A 💬 1件: Dopaminergic synapse Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
43 SCN1A 💬 1件: Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
44 SCN1A 💬 1件: Dopaminergic synapse Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
45 SCN1A 💬 1件: Dopaminergic synapse Oxybuprocaine 💬 Oxybuprocaine 1件: 6 💬
46 SCN1A 💬 1件: Dopaminergic synapse Quinidine 💬 Quinidine 3件: 2, 8, 13 💬
47 SCN1A 💬 1件: Dopaminergic synapse Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
48 SCN1A 💬 1件: Dopaminergic synapse Eleclazine 💬 Eleclazine 1件: 58 💬
49 SCN2A 💬 1件: Taste transduction Carbamazepine 💬 Carbamazepine 3件: 6, 13, 231 💬
50 SCN2A 💬 1件: Taste transduction Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
51 SCN2A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
52 SCN2A 💬 1件: Taste transduction Phenytoin 💬 Phenytoin 1件: 13 💬
53 SCN2A 💬 1件: Taste transduction Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
54 SCN2A 💬 1件: Taste transduction Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
55 SCN2A 💬 1件: Taste transduction Zonisamide 💬 Zonisamide 1件: 6 💬
56 SCN2A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 2件: 28, 127 💬
57 SCN2A 💬 1件: Taste transduction Cifenline 💬 Cibenzoline 1件: 58 💬
58 SCN2A 💬 1件: Taste transduction Rufinamide 💬 Rufinamide 1件: 144 💬
59 SCN2A 💬 1件: Taste transduction Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
60 SCN2A 💬 1件: Taste transduction Flecainide 💬 Flecainide 1件: 6 💬
61 SCN2A 💬 1件: Taste transduction Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
62 SCN2A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
63 SCN2A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
64 SCN2A 💬 1件: Taste transduction Oxybuprocaine 💬 Oxybuprocaine 1件: 6 💬
65 SCN2A 💬 1件: Taste transduction Quinidine 💬 Quinidine 3件: 2, 8, 13 💬
66 SCN2A 💬 1件: Taste transduction Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
67 SCN2A 💬 1件: Taste transduction Eleclazine 💬 Eleclazine 1件: 58 💬
68 SCN3A 💬 1件: Taste transduction Carbamazepine 💬 Carbamazepine 3件: 6, 13, 231 💬
69 SCN3A 💬 1件: Taste transduction Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
70 SCN3A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
71 SCN3A 💬 1件: Taste transduction Phenytoin 💬 Phenytoin 1件: 13 💬
72 SCN3A 💬 1件: Taste transduction Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
73 SCN3A 💬 1件: Taste transduction Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
74 SCN3A 💬 1件: Taste transduction Zonisamide 💬 Zonisamide 1件: 6 💬
75 SCN3A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 2件: 28, 127 💬
76 SCN3A 💬 1件: Taste transduction Cifenline 💬 Cibenzoline 1件: 58 💬
77 SCN3A 💬 1件: Taste transduction Rufinamide 💬 Rufinamide 1件: 144 💬
78 SCN3A 💬 1件: Taste transduction Lacosamide 💬 Lacosamide 4件: 2, 46, 149, 298 💬
79 SCN3A 💬 1件: Taste transduction Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
80 SCN3A 💬 1件: Taste transduction Flecainide 💬 Flecainide 1件: 6 💬
81 SCN3A 💬 1件: Taste transduction Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
82 SCN3A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
83 SCN3A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
84 SCN3A 💬 1件: Taste transduction Oxybuprocaine 💬 Oxybuprocaine 1件: 6 💬
85 SCN3A 💬 1件: Taste transduction Quinidine 💬 Quinidine 3件: 2, 8, 13 💬
86 SCN3A 💬 1件: Taste transduction Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
87 SCN3A 💬 1件: Taste transduction Eleclazine 💬 Eleclazine 1件: 58 💬
88 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Carbamazepine 💬 Carbamazepine 3件: 6, 13, 231 💬
89 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
90 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Lidocaine 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
91 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Phenytoin 💬 Phenytoin 1件: 13 💬
92 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
93 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
94 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Zonisamide 💬 Zonisamide 1件: 6 💬
95 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Amiodarone 💬 Amiodarone 2件: 28, 127 💬
96 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Cifenline 💬 Cibenzoline 1件: 58 💬
97 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Rufinamide 💬 Rufinamide 1件: 144 💬
98 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
99 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Flecainide 💬 Flecainide 1件: 6 💬
100 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
101 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
102 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
103 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Oxybuprocaine 💬 Oxybuprocaine 1件: 6 💬
104 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Quinidine 💬 Quinidine 3件: 2, 8, 13 💬
105 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
106 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Eleclazine 💬 Eleclazine 1件: 58 💬
107 SCN9A 💬 1件: Taste transduction Carbamazepine 💬 Carbamazepine 3件: 6, 13, 231 💬
108 SCN9A 💬 1件: Taste transduction Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
109 SCN9A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
110 SCN9A 💬 1件: Taste transduction Phenytoin 💬 Phenytoin 1件: 13 💬
111 SCN9A 💬 1件: Taste transduction Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
112 SCN9A 💬 1件: Taste transduction Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
113 SCN9A 💬 1件: Taste transduction Zonisamide 💬 Zonisamide 1件: 6 💬
114 SCN9A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 2件: 28, 127 💬
115 SCN9A 💬 1件: Taste transduction Cifenline 💬 Cibenzoline 1件: 58 💬
116 SCN9A 💬 1件: Taste transduction Rufinamide 💬 Rufinamide 1件: 144 💬
117 SCN9A 💬 1件: Taste transduction Lacosamide 💬 Lacosamide 4件: 2, 46, 149, 298 💬
118 SCN9A 💬 1件: Taste transduction Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
119 SCN9A 💬 1件: Taste transduction Flecainide 💬 Flecainide 1件: 6 💬
120 SCN9A 💬 1件: Taste transduction Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
121 SCN9A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
122 SCN9A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
123 SCN9A 💬 1件: Taste transduction Oxybuprocaine 💬 Oxybuprocaine 1件: 6 💬
124 SCN9A 💬 1件: Taste transduction Quinidine 💬 Quinidine 3件: 2, 8, 13 💬
125 SCN9A 💬 1件: Taste transduction Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
126 SCN9A 💬 1件: Taste transduction Eleclazine 💬 Eleclazine 1件: 58 💬
127 SCNN1A 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
128 SCNN1B 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
129 SCNN1G 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
130 SLC5A2 💬 - Dapagliflozin 💬 Dapagliflozin 7件: 19, 49, 66, 67, 86, 88, 222 💬
131 SLC5A2 💬 - Empagliflozin 💬 Empagliflozin 6件: 58, 65, 67, 72, 97, 257 💬
132 SLC6A1 💬 2件: Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin 5件: 6, 13, 19, 70, 298 💬
133 SLC6A2 💬 1件: Synaptic vesicle cycle Amoxapine 💬 Amoxapine 1件: 46 💬
134 SLC6A2 💬 1件: Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
135 SLC6A2 💬 1件: Synaptic vesicle cycle Phentermine 💬 Phentermine 1件: 97 💬
136 SLC6A2 💬 1件: Synaptic vesicle cycle Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬
137 SLC6A2 💬 1件: Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine 4件: 6, 8, 13, 17 💬
138 SLC6A2 💬 1件: Synaptic vesicle cycle Bupropion 💬 Bupropion 5件: 8, 18, 21, 96, 171 💬
139 SLC6A2 💬 1件: Synaptic vesicle cycle Desipramine 💬 Desipramine 2件: 120, 156 💬
140 SLC6A2 💬 1件: Synaptic vesicle cycle Doxepin 💬 Doxepin 1件: 6 💬
141 SLC6A2 💬 1件: Synaptic vesicle cycle Duloxetine 💬 Duloxetine 2件: 6, 13 💬
142 SLC6A2 💬 1件: Synaptic vesicle cycle Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬
143 SLC6A2 💬 1件: Synaptic vesicle cycle Milnacipran 💬 Milnacipran 2件: 46, 49 💬
144 SLC6A2 💬 1件: Synaptic vesicle cycle Nortriptyline 💬 Nortriptyline 2件: 6, 226 💬
145 SLC6A2 💬 1件: Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine 3件: 6, 13, 46 💬
146 SLC6A2 💬 1件: Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine 2件: 6, 17 💬
147 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Armodafinil 💬 Armodafinil 3件: 6, 13, 84 💬
148 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
149 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine 1件: 97 💬
150 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion 5件: 8, 18, 21, 96, 171 💬
151 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬
152 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Amoxapine 💬 Amoxapine 1件: 46 💬
153 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
154 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline 2件: 6, 206 💬
155 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Paroxetine 💬 Paroxetine 4件: 6, 13, 46, 85 💬
156 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Phentermine 💬 Phentermine 1件: 97 💬
157 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬
158 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127 💬
159 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Desipramine 💬 Desipramine 2件: 120, 156 💬
160 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Doxepin 💬 Doxepin 1件: 6 💬
161 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine 2件: 6, 13 💬
162 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram 4件: 2, 6, 13, 46 💬
163 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
164 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Milnacipran 💬 Milnacipran 2件: 46, 49 💬
165 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Nortriptyline 💬 Nortriptyline 2件: 6, 226 💬
166 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Trazodone 💬 Trazodone 1件: 2 💬
167 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine 3件: 6, 13, 46 💬
168 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine 1件: 6 💬
169 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine 2件: 6, 17 💬
170 SLC10A1 💬 2件: Bile secretion, Hepatitis B Maralixibat 💬 Maralixibat 3件: 296, 297, 338 💬
171 SLC10A2 💬 1件: Bile secretion Elobixibat 💬 Elobixibat 1件: 6 💬
172 SLC10A2 💬 1件: Bile secretion Maralixibat 💬 Maralixibat 3件: 296, 297, 338 💬
173 SLC10A2 💬 1件: Bile secretion Odevixibat 💬 Odevixibat 3件: 296, 297, 338 💬
174 SLC12A2 💬 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Bumetanide 💬 Bumetanide 2件: 6, 158 💬
175 SLC12A2 💬 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Furosemide 💬 Furosemide 2件: 6, 86 💬
176 SLC12A3 💬 - Hydrochlorothiazide 💬 Hydrochlorothiazide 4件: 13, 67, 225, 235 💬
177 SLC12A3 💬 - Indapamide 💬 Indapamide 1件: 13 💬
178 SLC12A3 💬 - Chlorothiazide 💬 Chlorothiazide 1件: 225 💬
179 SLC12A3 💬 - Bendroflumethiazide 💬 Bendroflumethiazide 1件: 67 💬
180 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Tetrabenazine 💬 Tetrabenazine 1件: 8 💬
181 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine 💬 Valbenazine 1件: 8 💬
182 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Deutetrabenazine 💬 Deutetrabenazine 1件: 8 💬
183 SMN1 💬 - Onasemnogene abeparvovec 💬 Onasemnogene abeparvovec 1件: 3 💬
184 SMN2 💬 - Nusinersen 💬 Nusinersen 1件: 3 💬
185 SMN2 💬 1件: Nucleocytoplasmic transport Risdiplam 💬 Risdiplam 1件: 3 💬
186 SMN2 💬 - Branaplam 💬 Branaplam 2件: 3, 8 💬
187 SMO 💬 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma Vismodegib 💬 Vismodegib 1件: 85 💬
188 SMO 💬 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma Taladegib 💬 Taladegib 1件: 85 💬
189 SMPD1 💬 5件: Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Necroptosis Olipudase alfa 💬 Olipudase alfa 1件: 19 💬
190 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
191 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Rimabotulinumtoxin B 💬 Botulinum toxin type B 4件: 2, 6, 13, 51 💬
192 SNCA 💬 3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Prasinezumab 💬 Prasinezumab 1件: 6 💬
193 SOD1 💬 8件: Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen 1件: 2 💬
194 SRC 💬 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Bosutinib 💬 Bosutinib 2件: 2, 67 💬
195 SRC 💬 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Dasatinib 💬 Dasatinib 2件: 51, 85 💬
196 SRC 💬 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Dasatinib 💬 Dasatinib 2件: 51, 85 💬
197 SRC 💬 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Saracatinib 💬 Saracatinib 3件: 6, 89, 272 💬
198 SRD5A1 💬 2件: Steroid hormone biosynthesis, Metabolic pathways Dutasteride 💬 Dutasteride 2件: 1, 2 💬
199 SRD5A2 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Finasteride 💬 Finasteride 1件: 6 💬
200 SRD5A2 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Dutasteride 💬 Dutasteride 2件: 1, 2 💬
201 SSTR1 💬 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin 2件: 67, 78 💬
202 SSTR1 💬 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide 3件: 67, 74, 75 💬
203 SSTR2 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
204 SSTR2 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Somatostatin 💬 Somatostatin 2件: 67, 78 💬
205 SSTR2 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Pasireotide 💬 Pasireotide 3件: 67, 74, 75 💬
206 SSTR3 💬 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin 2件: 67, 78 💬
207 SSTR3 💬 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide 3件: 67, 74, 75 💬
208 SSTR4 💬 1件: Neuroactive ligand-receptor interaction Somatostatin 💬 Somatostatin 2件: 67, 78 💬
209 SSTR5 💬 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin 2件: 67, 78 💬
210 SSTR5 💬 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide 3件: 67, 74, 75 💬
211 SYK 💬 17件: NF-kappa B signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Osteoclast differentiation, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease - COVID-19, Viral carcinogenesis Fostamatinib 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
212 S1PR4 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod 1件: 97 💬
213 S1PR4 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
214 S1PR4 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
215 S1PR2 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod 1件: 97 💬
216 S1PR2 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
217 S1PR2 💬 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
218 SV2B 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬
219 SV2A 💬 1件: ECM-receptor interaction Levetiracetam 💬 Levetiracetam 5件: 2, 4, 6, 13, 307 💬
220 SV2A 💬 1件: ECM-receptor interaction Brivaracetam 💬 Brivaracetam 2件: 149, 309 💬
221 SV2A 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬