Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Diabetic cardiomyopathy 💬
1件: ACE 💬 Benazepril 💬 Benazepril 4件: 49, 57, 218, 224 💬 💬
2 Diabetic cardiomyopathy 💬
1件: ACE 💬 Captopril 💬 Captopril 8件:  6 , 17, 46, 86, 96, 97, 107, 271 💬 💬
3 Diabetic cardiomyopathy 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬 💬
4 Diabetic cardiomyopathy 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬 💬
5 Diabetic cardiomyopathy 💬
1件: ACE 💬 Enalapril 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬 💬
6 Diabetic cardiomyopathy 💬
1件: ACE 💬 Imidapril 💬 Imidapril 1件: 67 💬 💬
7 Diabetic cardiomyopathy 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬 💬
8 Diabetic cardiomyopathy 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬 💬
9 Diabetic cardiomyopathy 💬
1件: ACE 💬 Moexipril 💬 Moexipril 1件: 93 💬 💬
10 Diabetic cardiomyopathy 💬
1件: ACE 💬 Perindopril 💬 Perindopril 4件: 58, 113, 167, 222 💬 💬
11 Diabetic cardiomyopathy 💬
1件: ACE 💬 Quinapril 💬 Quinapril 1件: 19 💬 💬
12 Diabetic cardiomyopathy 💬
1件: ACE 💬 Ramipril 💬 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257 💬 💬
13 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
14 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
15 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬 💬
16 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil 1件: 67 💬 💬
17 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬 💬
18 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Losartan 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬
19 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬 💬
20 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬 💬
21 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Valsartan 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬 💬
22 Diabetic cardiomyopathy 💬
2件: CPT1B, CPT2 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬 💬
23 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin detemir 💬 Insulin detemir 1件: 299 💬 💬
24 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin glargine 💬 Insulin glargine 1件: 299 💬 💬
25 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
26 Diabetic cardiomyopathy 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
27 Diabetic cardiomyopathy 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
28 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
29 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
30 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
31 Diabetic cardiomyopathy 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
32 Diabetic cardiomyopathy 💬
1件: PARP1 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬 💬
33 Diabetic cardiomyopathy 💬
3件: PDK2, PDK3, PDK4 💬 Sodium dichloroacetate 💬 Sodium dichloroacetate 1件: 86 💬 💬
34 Diabetic cardiomyopathy 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
35 Diabetic cardiomyopathy 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
36 Diabetic cardiomyopathy 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
37 Diabetic cardiomyopathy 💬
1件: PPARA 💬 Bezafibrate 💬 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324 💬 💬
38 Diabetic cardiomyopathy 💬
1件: PPARA 💬 Elafibranor 💬 Elafibranor 2件: 93, 94 💬 💬
39 Diabetic cardiomyopathy 💬
1件: PPARA 💬 Fenofibrate 💬 Fenofibrate 6件:  8 , 79, 93, 94, 97, 265 💬 💬
40 Diabetic cardiomyopathy 💬
1件: PPARA 💬 Pemafibrate 💬 Pemafibrate 1件: 93 💬 💬
41 Diabetic cardiomyopathy 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
42 Diabetic cardiomyopathy 💬
1件: PRKCD 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬 💬
43 Diabetic cardiomyopathy 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
44 Diabetic cardiomyopathy 💬
1件: REN 💬 Aliskiren 💬 Aliskiren 3件: 66, 167, 222 💬 💬
45 Diabetic cardiomyopathy 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬 💬
46 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬 💬
47 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Atenolol 💬 Atenolol 1件: 167 💬 💬
48 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
49 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
50 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Celiprolol 💬 Celiprolol 1件: 168 💬 💬
51 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬 💬
52 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
53 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬 💬
54 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Ephedrine 💬 Ephedrine 1件: 11 💬 💬
55 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Epinephrine 💬 Epinephrine 3件: 46, 70, 96 💬 💬
56 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Esmolol 💬 Esmolol 1件: 58 💬 💬
57 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Metoprolol 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬 💬
58 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Nadolol 💬 Nadolol 1件:  6  💬 💬
59 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Nebivolol 💬 Nebivolol 4件: 17, 85, 113, 167 💬 💬
60 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬 💬
61 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Propranolol 💬 Propranolol 6件:  6 , 158, 167, 227, 278, 296 💬 💬
62 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬 💬
63 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Timolol 💬 Timolol 2件: 157, 227 💬 💬
64 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Timolol 💬 Timolol 2件: 157, 227 💬 💬
65 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
66 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬 💬
67 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
68 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬 💬
69 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
70 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬 💬
71 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬 💬
72 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬 💬
73 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬 💬
74 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
75 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬 💬
76 Dilated cardiomyopathy 💬
2件: CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin 1件: 70 💬 💬
77 Dilated cardiomyopathy 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬 💬
78 Dilated cardiomyopathy 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬 💬
79 Dilated cardiomyopathy 💬
1件: DMD 💬 Casimersen 💬 Casimersen 1件: 113 💬 💬
80 Dilated cardiomyopathy 💬
1件: DMD 💬 Drisapersen 💬 Drisapersen 1件: 113 💬 💬
81 Dilated cardiomyopathy 💬
1件: DMD 💬 Eteplirsen 💬 Eteplirsen 1件: 113 💬 💬
82 Dilated cardiomyopathy 💬
1件: DMD 💬 Golodirsen 💬 Golodirsen 1件: 113 💬 💬
83 Dilated cardiomyopathy 💬
1件: DMD 💬 Viltolarsen 💬 Viltolarsen 1件: 113 💬 💬
84 Dilated cardiomyopathy 💬
1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬 💬
85 Dilated cardiomyopathy 💬
1件: ITGA4 💬 Natalizumab 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬 💬
86 Dilated cardiomyopathy 💬
2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬 💬
87 Dilated cardiomyopathy 💬
2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬 💬
88 Dilated cardiomyopathy 💬
1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬 💬
89 Dilated cardiomyopathy 💬
1件: MYH7 💬 Mavacamten 💬 Mavacamten 1件: 58 💬 💬
90 Dilated cardiomyopathy 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬 💬
91 Dilated cardiomyopathy 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
92 Dilated cardiomyopathy 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
93 Dilated cardiomyopathy 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
94 Dilated cardiomyopathy 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
95 Dilated cardiomyopathy 💬
1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
96 Dilated cardiomyopathy 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
97 Dilated cardiomyopathy 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
98 Dilated cardiomyopathy 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
99 Dilated cardiomyopathy 💬
1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
100 Dilated cardiomyopathy 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
101 Dilated cardiomyopathy 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬
102 DNA replication 💬
2件: POLA1, POLA2 💬 Clofarabine 💬 Clofarabine 5件: 19, 20, 60, 234, 326 💬 💬
103 Dopaminergic synapse 💬
3件: CACNA1B, CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬 💬
104 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
105 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
106 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Isradipine 💬 Isradipine 1件:  6  💬 💬
107 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
108 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬 💬
109 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬 💬
110 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬 💬
111 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Propiverine 💬 Propiverine 1件: 226 💬 💬
112 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬 💬
113 Dopaminergic synapse 💬
7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
114 Dopaminergic synapse 💬
1件: COMT 💬 Entacapone 💬 Entacapone 2件:  6 , 17 💬 💬
115 Dopaminergic synapse 💬
1件: COMT 💬 Opicapone 💬 Opicapone 1件:  6  💬 💬
116 Dopaminergic synapse 💬
1件: COMT 💬 Tolcapone 💬 Tolcapone 3件:  6 , 28, 127 💬 💬
117 Dopaminergic synapse 💬
1件: DDC 💬 Benserazide 💬 Benserazide 1件:  6  💬 💬
118 Dopaminergic synapse 💬
1件: DDC 💬 Carbidopa 💬 Carbidopa 7件:  6 , 13, 17, 90, 140, 164, 201 💬 💬
119 Dopaminergic synapse 💬
2件: DRD1, DRD2 💬 Apomorphine 💬 Apomorphine 3件:  5 ,  6 ,  7  💬 💬
120 Dopaminergic synapse 💬
2件: DRD1, DRD2 💬 Flupentixol 💬 Flupentixol 1件: 97 💬 💬
121 Dopaminergic synapse 💬
2件: DRD1, DRD2 💬 Pergolide 💬 Pergolide 1件:  6  💬 💬
122 Dopaminergic synapse 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole 1件:  2  💬 💬
123 Dopaminergic synapse 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬 💬
124 Dopaminergic synapse 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa 1件:  6  💬 💬
125 Dopaminergic synapse 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa 6件:  6 , 17, 90, 140, 164, 201 💬 💬
126 Dopaminergic synapse 💬
2件: DRD1, DRD5 💬 Tavapadon 💬 Tavapadon 1件:  6  💬 💬
127 Dopaminergic synapse 💬
1件: DRD2 💬 Bromocriptine 💬 Bromocriptine 2件:  6 , 74 💬 💬
128 Dopaminergic synapse 💬
1件: DRD2 💬 Buspirone 💬 Buspirone 2件:  6 , 51 💬 💬
129 Dopaminergic synapse 💬
1件: DRD2 💬 Cabergoline 💬 Cabergoline 3件:  6 , 74, 75 💬 💬
130 Dopaminergic synapse 💬
1件: DRD2 💬 Cariprazine 💬 Cariprazine 1件: 21 💬 💬
131 Dopaminergic synapse 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬 💬
132 Dopaminergic synapse 💬
1件: DRD2 💬 Domperidone 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
133 Dopaminergic synapse 💬
1件: DRD2 💬 Domperidone maleate 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
134 Dopaminergic synapse 💬
1件: DRD2 💬 Haloperidol 💬 Haloperidol 1件:  8  💬 💬
135 Dopaminergic synapse 💬
1件: DRD2 💬 Iloperidone 💬 Iloperidone 1件:  6  💬 💬
136 Dopaminergic synapse 💬
1件: DRD2 💬 Melperone 💬 Melperone 1件:  6  💬 💬
137 Dopaminergic synapse 💬
1件: DRD2 💬 Metoclopramide 💬 Metoclopramide 2件: 46, 51 💬 💬
138 Dopaminergic synapse 💬
1件: DRD2 💬 Pimozide 💬 Pimozide 1件:  2  💬 💬
139 Dopaminergic synapse 💬
1件: DRD2 💬 Pridopidine 💬 Pridopidine 3件:  2 ,  6 ,  8  💬 💬
140 Dopaminergic synapse 💬
1件: DRD2 💬 Quetiapine 💬 Quetiapine 2件:  6 , 13 💬 💬
141 Dopaminergic synapse 💬
1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
142 Dopaminergic synapse 💬
1件: DRD2 💬 Rotigotine 💬 Rotigotine 1件:  6  💬 💬
143 Dopaminergic synapse 💬
1件: DRD2 💬 Sulpiride 💬 Sulpiride 2件:  6 , 70 💬 💬
144 Dopaminergic synapse 💬
1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
145 Dopaminergic synapse 💬
1件: DRD2 💬 Tiapride 💬 Tiapride 1件:  8  💬 💬
146 Dopaminergic synapse 💬
1件: DRD2 💬 Trifluoperazine maleate 💬 Trifluoperazine 2件: 283, 284 💬 💬
147 Dopaminergic synapse 💬
1件: DRD2 💬 Trifluoperazine 💬 Trifluoperazine 2件: 283, 284 💬 💬
148 Dopaminergic synapse 💬
2件: DRD2, DRD3 💬 Aripiprazole 💬 Aripiprazole 2件:  6 , 206 💬 💬
149 Dopaminergic synapse 💬
2件: DRD2, DRD3 💬 Pardoprunox 💬 Pardoprunox 1件:  6  💬 💬
150 Dopaminergic synapse 💬
2件: DRD2, DRD3 💬 Piribedil 💬 Piribedil 1件:  6  💬 💬
151 Dopaminergic synapse 💬
3件: DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
152 Dopaminergic synapse 💬
3件: DRD2, DRD3, DRD4 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬 💬
153 Dopaminergic synapse 💬
3件: DRD2, DRD3, DRD4 💬 Pramipexole 💬 Pramipexole 3件:  2 ,  6 , 20 💬 💬
154 Dopaminergic synapse 💬
3件: DRD2, DRD3, DRD4 💬 Ropinirole 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬 💬
155 Dopaminergic synapse 💬
1件: DRD4 💬 Clozapine 💬 Clozapine 1件:  6  💬 💬
156 Dopaminergic synapse 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬 💬
157 Dopaminergic synapse 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬 💬
158 Dopaminergic synapse 💬
6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
159 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate 2件:  6 , 206 💬 💬
160 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
161 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
162 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine 3件:  2 ,  4 , 70 💬 💬
163 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
164 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬 💬
165 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
166 Dopaminergic synapse 💬
3件: KCNJ3, KCNJ5, SCN1A 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬 💬
167 Dopaminergic synapse 💬
1件: MAOA 💬 Moclobemide 💬 Moclobemide 1件:  6  💬 💬
168 Dopaminergic synapse 💬
2件: MAOA, MAOB 💬 Iproniazid 💬 Iproniazid 1件:  6  💬 💬
169 Dopaminergic synapse 💬
2件: MAOA, MAOB 💬 Phenelzine 💬 Phenelzine 1件:  6  💬 💬
170 Dopaminergic synapse 💬
3件: MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine 1件: 97 💬 💬
171 Dopaminergic synapse 💬
1件: MAOB 💬 Rasagiline 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬 💬
172 Dopaminergic synapse 💬
1件: MAOB 💬 Rasagiline tartrate 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬 💬
173 Dopaminergic synapse 💬
1件: MAOB 💬 Safinamide 💬 Safinamide 2件:  6 , 17 💬 💬
174 Dopaminergic synapse 💬
1件: MAOB 💬 Selegiline 💬 Selegiline 1件:  6  💬 💬
175 Dopaminergic synapse 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
176 Dopaminergic synapse 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
177 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
178 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬 💬
179 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
180 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
181 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬 💬
182 Dopaminergic synapse 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
183 Dopaminergic synapse 💬
1件: SCN1A 💬 Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬 💬
184 Dopaminergic synapse 💬
1件: SCN1A 💬 Carbamazepine 💬 Carbamazepine 3件:  6 , 13, 231 💬 💬
185 Dopaminergic synapse 💬
1件: SCN1A 💬 Cifenline 💬 Cibenzoline 1件: 58 💬 💬
186 Dopaminergic synapse 💬
1件: SCN1A 💬 Eleclazine 💬 Eleclazine 1件: 58 💬 💬
187 Dopaminergic synapse 💬
1件: SCN1A 💬 Flecainide 💬 Flecainide 1件:  6  💬 💬
188 Dopaminergic synapse 💬
1件: SCN1A 💬 Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬 💬
189 Dopaminergic synapse 💬
1件: SCN1A 💬 Levobupivacaine 💬 Levobupivacaine 1件: 46 💬 💬
190 Dopaminergic synapse 💬
1件: SCN1A 💬 Lidocaine 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
191 Dopaminergic synapse 💬
1件: SCN1A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
192 Dopaminergic synapse 💬
1件: SCN1A 💬 Mexiletine 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬 💬
193 Dopaminergic synapse 💬
1件: SCN1A 💬 Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬 💬
194 Dopaminergic synapse 💬
1件: SCN1A 💬 Oxybuprocaine 💬 Oxybuprocaine 1件:  6  💬 💬
195 Dopaminergic synapse 💬
1件: SCN1A 💬 Phenytoin 💬 Phenytoin 1件: 13 💬 💬
196 Dopaminergic synapse 💬
1件: SCN1A 💬 Quinidine 💬 Quinidine 3件:  2 ,  8 , 13 💬 💬
197 Dopaminergic synapse 💬
1件: SCN1A 💬 Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬 💬
198 Dopaminergic synapse 💬
1件: SCN1A 💬 Rufinamide 💬 Rufinamide 1件: 144 💬 💬
199 Dopaminergic synapse 💬
1件: SCN1A 💬 Zonisamide 💬 Zonisamide 1件:  6  💬 💬
200 Dopaminergic synapse 💬
1件: SLC18A2 💬 Deutetrabenazine 💬 Deutetrabenazine 1件:  8  💬 💬
201 Dopaminergic synapse 💬
1件: SLC18A2 💬 Tetrabenazine 💬 Tetrabenazine 1件:  8  💬 💬
202 Dopaminergic synapse 💬
1件: SLC18A2 💬 Valbenazine 💬 Valbenazine 1件:  8  💬 💬
203 Dopaminergic synapse 💬
1件: SLC6A3 💬 Armodafinil 💬 Armodafinil 3件:  6 , 13, 84 💬 💬
204 Dopaminergic synapse 💬
1件: SLC6A3 💬 Bupropion 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬 💬
205 Dopaminergic synapse 💬
1件: SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬 💬
206 Dopaminergic synapse 💬
1件: SLC6A3 💬 Methylphenidate 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬 💬
207 Drug metabolism - cytochrome P450 💬
3件: ADH1A, ADH1B, ADH1C 💬 Fomepizole 💬 Fomepizole 1件: 301 💬 💬
208 Drug metabolism - cytochrome P450 💬
1件: MAOA 💬 Moclobemide 💬 Moclobemide 1件:  6  💬 💬
209 Drug metabolism - cytochrome P450 💬
2件: MAOA, MAOB 💬 Iproniazid 💬 Iproniazid 1件:  6  💬 💬
210 Drug metabolism - cytochrome P450 💬
2件: MAOA, MAOB 💬 Phenelzine 💬 Phenelzine 1件:  6  💬 💬
211 Drug metabolism - cytochrome P450 💬
2件: MAOA, MAOB 💬 Phentermine 💬 Phentermine 1件: 97 💬 💬
212 Drug metabolism - cytochrome P450 💬
1件: MAOB 💬 Rasagiline 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬 💬
213 Drug metabolism - cytochrome P450 💬
1件: MAOB 💬 Rasagiline tartrate 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬 💬
214 Drug metabolism - cytochrome P450 💬
1件: MAOB 💬 Safinamide 💬 Safinamide 2件:  6 , 17 💬 💬
215 Drug metabolism - cytochrome P450 💬
1件: MAOB 💬 Selegiline 💬 Selegiline 1件:  6  💬 💬
216 Drug metabolism - other enzymes 💬
1件: GUSB 💬 Vestronidase alfa 💬 Vestronidase alfa 1件: 19 💬 💬
217 Drug metabolism - other enzymes 💬
1件: HPRT1 💬 Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬 💬
218 Drug metabolism - other enzymes 💬
1件: HPRT1 💬 Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬 💬
219 Drug metabolism - other enzymes 💬
1件: HPRT1 💬 Tioguanine 💬 Tioguanine 2件: 13, 37 💬 💬
220 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mizoribine 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬 💬
221 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolate mofetil 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬
222 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolic acid 💬 Mycophenolic acid 36件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬
223 Drug metabolism - other enzymes 💬
1件: MPO 💬 Verdiperstat 💬 Verdiperstat 3件:  2 , 17, 127 💬 💬
224 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Cladribine 💬 Cladribine 3件: 11, 13, 94 💬 💬
225 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Clofarabine 💬 Clofarabine 5件: 19, 20, 60, 234, 326 💬 💬
226 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Fludarabine 💬 Fludarabine 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬
227 Drug metabolism - other enzymes 💬
1件: RRM2 💬 Hydroxyurea 💬 Hydroxyurea 8件:  3 , 13, 19, 20, 65, 85, 86, 284 💬 💬
228 Drug metabolism - other enzymes 💬
1件: XDH 💬 Allopurinol 💬 Allopurinol 7件:  6 , 46, 57, 60, 66, 96, 97 💬 💬
229 Drug metabolism - other enzymes 💬
1件: XDH 💬 Febuxostat 💬 Febuxostat 3件:  2 ,  6 , 13 💬 💬