156. レット症候群 [臨床試験数:36,薬物数:49(DrugBank:19),標的遺伝子数:77,標的パスウェイ数:112

Searched query = "Rett syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
5 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01520363
(ClinicalTrials.gov)
March 201225/1/2012Placebo Controlled Trial of Dextromethorphan in Rett SyndromePlacebo Controlled Trial of Dextromethorphan in Rett SyndromeRett SyndromeDrug: dextromethorphan;Drug: placeboHugo W. Moser Research Institute at Kennedy Krieger, Inc.The Johns Hopkins Institute for Clinical and Translational Research (ICTR)Completed1 Year10 YearsAll57Phase 2United States
2NCT00069550
(ClinicalTrials.gov)
September 200429/9/2003Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett SyndromePathogenesis of Rett Syndrome: Natural History and TreatmentRett SyndromeDrug: dextromethorphan;Drug: donepezil hydrochlorideEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NULLRecruiting1 Year15 YearsBoth90Phase 3United States
3NCT00593957
(ClinicalTrials.gov)
August 20044/1/2008Trial of Dextromethorphan in Rett SyndromeTrial of Dextromethorphan in Rett SyndromeRett SyndromeDrug: DextromethorphanHugo W. Moser Research Institute at Kennedy Krieger, Inc.NULLTerminated2 Years15 YearsAll38Phase 2United States
4NCT00004807
(ClinicalTrials.gov)
January 199524/2/2000Study of the Pathogenesis of Rett SyndromeRett SyndromeDrug: dextromethorphan;Drug: topiramate;Drug: DonepezilEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Johns Hopkins UniversityCompletedN/A45 YearsBoth120N/ANULL
5EUCTR2008-005571-10-NO
(EUCTR)
09/01/2009DEXTROMETORPHAN IN RETT SYNDROMEDEXTROMETORPHAN IN RETT SYNDROME Rett syndrome (RTT) is a neurological disorder with devastating consequences on the brain. It is characterized by stagnation of development followed by regression, both occurring between age 6 months and 3 years. The clinical picture is dominated by cognitive impairment, loss of communication skills, purposeful hand movements, hand stereotypies, progressive deceleration of head growth, and abnormal locomotion. RTT syndrome presently has no effective therapy other than pallitative careProduct Name: DextromethorphanKennedy Krieger Inst. Johns Hopkins MedicineNULLNAFemale: yes
Male: no
90Phase 2Norway