206. 脆弱X症候群 [臨床試験数:98,薬物数:73(DrugBank:27),標的遺伝子数:46,標的パスウェイ数:57

Searched query = "Fragile X syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
4 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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agemax
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PhaseCountries
1NCT04141163
(ClinicalTrials.gov)
October 29, 201924/10/2019Metformin in Patients With Fragile XA Parallel Group Design Randomized Double-Blind Trial of Metformin Treatment in Patients With Fragile X Syndrome on Safety and Effects on Cognition, Anxiety, Attention and BiomarkersFragile X SyndromeDrug: Metformin;Drug: Placebo oral tabletRowan UniversityFRAXA Research Foundation;University of PennsylvaniaRecruiting18 Years50 YearsMale40Phase 1/Phase 2United States
2NCT03862950
(ClinicalTrials.gov)
May 24, 201926/2/2019A Trial of Metformin in Individuals With Fragile X Syndrome (Met)A Double-Blind, Placebo-Controlled Trial of Metformin in Individuals With Fragile X Syndrome (FXS)Fragile X Syndrome;Fragile X Mental Retardation Syndrome;Mental Retardation, X-Linked;Genetic Diseases, X-Linked;Trinucleotide Repeat Expansion;Fra(X) Syndrome;Intellectual Disability;FXS;Neurobehavioral Manifestations;Sex Chromosome DisordersDrug: Placebo Medication;Drug: MetforminUniversity of AlbertaSt. Justine's HospitalRecruiting6 Years25 YearsAll120Phase 2Canada
3NCT03722290
(ClinicalTrials.gov)
September 1, 201824/10/2018Metformin in Children and Adults With Fragile X SyndromeEvaluate the Efficacy and Safety of Metformin in Children and Adults With Fragile X Syndrome: an Open-label StudyFragile X SyndromeDrug: MetforminUniversité de SherbrookeFRAXA Research FoundationUnknown status10 Years40 YearsAll20Phase 2Canada
4NCT03479476
(ClinicalTrials.gov)
April 30, 201820/3/2018A Trial of Metformin in Individuals With Fragile X SyndromeA Double-Blind, Placebo-Controlled Trial of Metformin in Individuals With Fragile X SyndromeFragile X Syndrome;Fragile X Mental Retardation Syndrome;Mental Retardation, X Linked;Genetic Diseases, X-Linked;Trinucleotide Repeat Expansion;Fra(X) Syndrome;Intellectual Disability;FXS;Neurobehavioral Manifestations;Sex Chromosome DisordersDrug: Placebo Medication;Drug: MetforminUniversity of California, DavisNULLRecruiting6 Years25 YearsAll60Phase 2/Phase 3United States