210. 単心室症 [臨床試験数:47,薬物数:54(DrugBank:23),標的遺伝子数:32,標的パスウェイ数:66

Searched query = "Single Ventricle", "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulation syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
4 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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Inclusion_
agemin
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PhaseCountries
1NCT01292551
(ClinicalTrials.gov)
February 20118/2/2011Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology.Treatment With Endothelin Antagonist to Tcpc Patients; a Multicenter, Randomized, Prospective Study Measuring Maximal O2 Uptake in Ergometer Bicycle TestHypoplastic Left Heart Syndrome;Tricuspid Atresia;Other Specified Congenital Anomalies of HeartDrug: Bosentan;Drug: PlaceboRigshospitalet, DenmarkAarhus University Hospital;Bispebjerg Hospital;ActelionCompleted15 YearsN/ABoth75Phase 2Denmark;Sweden
2NCT00989911
(ClinicalTrials.gov)
May 20105/10/2009Endothelin Blockade in Patients With Single Ventricle PhysiologyEndothelin Blockade in Patients With Single Ventricle PhysiologyCongenital Heart DiseaseDrug: BosentanUniversity of California, Los AngelesActelionCompleted12 YearsN/AAll10N/AUnited States
3NCT01662037
(ClinicalTrials.gov)
January 20105/8/2012Bosentan Therapy in Children With Functional Single VentricleBosentan Therapy for High Risk Staged Fontan Procedure in Children With Functional Single VentricleCongenital Heart Defects;Functional Single VentricleDrug: BosentanShanghai Jiao Tong University School of MedicineNULLCompleted4 Months18 YearsBoth34Phase 2China
4EUCTR2005-005898-29-GB
(EUCTR)
04/07/200809/05/2008The effect of bosentan, a selective endothelin antagonist, on cardiovascular performance in patients with a Fontan circulation - Bosentan therapy in FontansThe effect of bosentan, a selective endothelin antagonist, on cardiovascular performance in patients with a Fontan circulation - Bosentan therapy in Fontans Patients with a Fontan circulation (that is they have had a Fontan operation for a functionally univentricular heart)
MedDRA version: 9.1;Level: LLT;Classification code 10045545;Term: Univentricular heart
MedDRA version: 9.1;Classification code 10065950;Term: Cavopulmonary anastomosis
MedDRA version: 9.1;Classification code 10037456;Term: Pulmonary vascular resistance abnormality
University Hospital BirminghamNULLNot Recruiting Female: yes
Male: yes
15 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesUnited Kingdom