26. HTLV-1関連脊髄症
[臨床試験数:26,薬物数:46(DrugBank:27),標的遺伝子数:37,標的パスウェイ数:123

Searched query = "HTLV-1-associated myelopathy", "Tropical spastic paraparesis", "HTLV-1", "HTLV-I-associated myelopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
4 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1NCT02655471
(ClinicalTrials.gov)
July 1, 201716/11/2015Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 InfectionEffect of Raltegravir in Patients With Myelopathy/Tropical Spastic Paraparesis Associated With Infection by Human T-Lymphotropic Virus 1 (HTLV-1). Pilot StudyHTLV-I Infections;Tropical Spastic ParaparesisDrug: Raltegravir and ZidovudineUniversidad Peruana Cayetano HerediaMerck Sharp & Dohme Corp.Completed18 YearsN/AAll10Early Phase 1Peru
2NCT01867320
(ClinicalTrials.gov)
September 5, 201321/5/2013Raltegravir for HAM/TSPPilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)HTLV-I InfectionDrug: RaltegravirNational Institute of Neurological Disorders and Stroke (NINDS)NULLCompleted18 YearsN/AAll19Early Phase 1United States
3NCT01620736
(ClinicalTrials.gov)
January 201225/1/2012Trial to Assess Effect of Raltegravir on HTLV-1 Proviral LoadPhase II Trial to Assess Effect of Raltegravir on HTLV-1 Proviral LoadHuman T-cell Leukemia Virus Type 1 InfectionDrug: RaltegravirWashington University School of MedicineMerck Sharp & Dohme Corp.Withdrawn18 YearsN/AAll0Phase 2United States
4NCT01000285
(ClinicalTrials.gov)
September 201019/10/2009EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia LymphomaPhase I/II Trial of Dose-Adjusted EPOCH Chemotherapy With Bortezomib Combined With Integrase Inhibitor Therapy for HTLV-1 Associated T-Cell Leukemia LymphomaLeukemia-Lymphoma, Adult T-CellDrug: Bortezomib;Drug: Etoposide;Drug: Vincristine;Drug: Doxorubicin;Drug: Prednisone;Drug: Cyclophosphamide;Drug: RaltegravirWashington University School of MedicineNULLCompleted18 YearsN/AAll18Phase 1/Phase 2United States