46. 悪性関節リウマチ [臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
13 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
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PhaseCountries
1NCT04509427
(ClinicalTrials.gov)
October 202029/6/2020EXercise and PosturE in Individuals With Rheumatoid ArthriTIs and OStEoporosisComparison of Video-based and Paper Instructional Material to Promote EXercise and PosturE in Individuals With Rheumatoid ArthrTIs and OStEoporosisRheumatoid Arthritis;OsteoporosisBehavioral: Instructional handouts;Behavioral: Physical therapist instruction and monitoring via teleconferencing;Behavioral: Web-based instructional videos;Behavioral: Posture training;Behavioral: Resistance exercise;Behavioral: Balance exercise;Behavioral: Marching in placeUniversity of Alabama at BirminghamNULLNot yet recruiting51 YearsN/AFemale24N/ANULL
2NCT04194827
(ClinicalTrials.gov)
March 1, 20203/12/2019Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug MonitoringAdalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA): Multi-centre Open Label Randomised Controlled TrailRheumatoid ArthritisDiagnostic Test: Adalimumab serum trough concentration;Diagnostic Test: Disease activity;Drug: AdalimumabReade Rheumatology Research InstituteZonMw: The Netherlands Organisation for Health Research and Development;Sint MaartenskliniekRecruiting18 YearsN/AAll267Phase 4Netherlands
3EUCTR2018-004429-94-NL
(EUCTR)
21/01/202017/06/2019Monitoring of respons to therapy in rheumatoid arthritis with the help of a PET scan.[18F]PEG-folate PET-CT imaging for monitoring of therapy response in rheumatoid arthritis patients Rheumatoid Arthritis;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]Product Name: [18F]PEG-FolateVU Medical Center, department of RheumatologyNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
10Phase 4Netherlands
4EUCTR2019-001554-25-NL
(EUCTR)
29/10/201929/10/2019 Adalimumab dose optimization in rheumatoid arthritis using drug concentration in blood (ADDORA): multi-center open label randomized controlled trail Adalimumab dose optimization in rheumatoid arthritis using therapeutic drug monitoring (ADDORA): multi-center open label randomized controlled trail - ADalimumab Dose Optimization in Rheumatoid Arthritis using (ADDORA) Rheumatoid arthritis;Therapeutic area: Diseases [C] - Immune System Diseases [C20]ReadeNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
267 Human pharmacology (Phase 1): yes Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesNetherlands
5NCT03781310
(ClinicalTrials.gov)
December 201817/12/2018Therapeutic Drug Monitoring of Tocilizumab in Rheumatoid ArthritisTherapeutic Drug Monitoring of Tocilizumab in Rheumatoid ArthritisRheumatoid Arthritis;TocilizumabDrug: TocilizumabTel-Aviv Sourasky Medical CenterAmsterdam Rheumatology and Immunology CenterUnknown status18 YearsN/AAll80Phase 4Israel
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT03480529
(ClinicalTrials.gov)
March 1, 201821/3/2018Monitoring the IMmUological TOXicity of DrugsMonitoring the IMmUological TOXicity of DrugsArthritis;Systemic Lupus Erythematosus;Rheumatoid Arthritis;Capillary Leak Syndrome;HepatitisDrug: drug inducing arthritis, lupus, hepatitis, or capillary leak syndromGroupe Hospitalier Pitie-SalpetriereInstitut National de la Santé Et de la Recherche Médicale, FranceCompleted18 YearsN/AAll662France
7EUCTR2013-004006-26-DK
(EUCTR)
18/12/201318/12/2013OPALOptical images for monitoring treatment changes in rheumatoid arthritis – a longitudinal study with Rheumascan Detection of synovitis and tenosynovitis in the hands of patients with rheumatoid arthritis; Diagnostic performance of optical imaging in comparison with ultrasound and magnetic resonance imaging.
MedDRA version: 16.1;Level: LLT;Classification code 10067132;Term: Synovitis wrist;System Organ Class: 100000004859;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Trade Name: ICG-Pulsion
INN or Proposed INN: 2-{7-[1,1-dimethyl-3-(4-sulfobutyl)-benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl}-1,1-dimethyl-3-(sulfobutyl)-1H-benz[e]-indolium hydroxide,inner salt
Other descriptive name: INDOCYANINE GREEN
Knowledge Centre for Rheumatology and Back DiseasesNULLNot RecruitingFemale: yes
Male: yes
Phase 4Denmark
8NCT01619176
(ClinicalTrials.gov)
October 20125/6/2012Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and BloodNon Inferiority Trial for the Study of Acupuncture on Rheumatoid ArthritisRheumatoid ArthritisDrug: methotrexate;Drug: non-steroidal anti-inflammatory drug (NSAID);Drug: leflunomide;Procedure: AcupunctureChinese Academy of SciencesShanghai GuangHua Hospital of integrated traditional and western medicineCompleted18 Years65 YearsFemale15N/AChina
9NCT01282528
(ClinicalTrials.gov)
September 201024/1/2011Ultrasonographic Monitoring of Response to Infliximab in Patients With Rheumatoid ArthritisUltrasonographic Monitoring of Response to Infliximab in Patients With Rheumatoid ArthritisRheumatoid Arthritis;Ultrasonography;InfliximabBiological: infliximabPeking Union Medical College HospitalShanghai Changzheng Hospital;First Hospital of China Medical University;Shenzhen People's Hospital;Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;Wenzhou Medical University;First People's Hospital of Foshan;West China HospitalRecruiting18 Years65 YearsBoth85Phase 4China
10EUCTR2008-005450-20-BE
(EUCTR)
29/10/200901/10/2009The cost-effectiveness of abatacept, rituximab or anti-TNF alpha for patients with rheumatoid artritis. - Dutch Rheumatoid Arthritis Monitoring (DREAM) Targetted Immune Modulator Evaluation (TIME)The cost-effectiveness of abatacept, rituximab or anti-TNF alpha for patients with rheumatoid artritis. - Dutch Rheumatoid Arthritis Monitoring (DREAM) Targetted Immune Modulator Evaluation (TIME) Rheumatoid arthritis
MedDRA version: 12.0;Level: PT;Classification code 10039073;Term: Rheumatoid arthritis
Trade Name: Remicade (infliximab)
INN or Proposed INN: INFLIXIMAB
Other descriptive name: remicade
Trade Name: Humira (adalimumab)
INN or Proposed INN: ADALIMUMAB
Trade Name: Enbrel (etanercept)
INN or Proposed INN: ETANERCEPT
Other descriptive name: Enbrel
Trade Name: Mabthera (rituximab)
INN or Proposed INN: RITUXIMAB
Other descriptive name: Mabthera
Trade Name: Orencia (abatacept)
INN or Proposed INN: ABATACEPT
Other descriptive name: Orencia
Radboud University Nijmegen Medical Centre, department of Rheumatic DiseasesNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
261Belgium
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
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Inclusion_
agemin
Inclusion_
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Inclusion_
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PhaseCountries
11NCT03681639
(ClinicalTrials.gov)
August 1, 200913/9/2018Metasul Monoblock Component™ Cup in a Hip Resurfacing Application With the Durom® Hip Resurfacing Femoral ComponentA Multi-Centre, Prospective Study to Obtain Survival and Clinical Outcome Data on the Zimmer Hip Resurfacing System Utilising the Metasul Monoblock Component™ Cup in a Hip Resurfacing Application With the Durom® Hip Resurfacing Femoral ComponentAvascular Necrosis of Hip;Osteoarthritis, Hip;Rheumatoid Arthritis;Inflammatory Arthritis;Post-traumatic; ArthrosisDiagnostic Test: Serum Metal ion levels determined to monitor changes in chromium and cobalt levelsZimmer BiometNULLActive, not recruiting18 Years65 YearsAll225N/AGermany
12NCT00947492
(ClinicalTrials.gov)
June 200927/7/2009Monitoring Epstein-Barr Virus (EBV) Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive DrugsMonitoring EBV Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs ; Orencia* (Abatacept) and RoActemra* (Tocilizumab).Rheumatoid ArthritisBiological: Venous blood sampleAssistance Publique Hopitaux De MarseilleNULLActive, not recruiting18 YearsN/ABoth60N/AFrance
13NCT00725621
(ClinicalTrials.gov)
March 200425/7/2008Real Life Dosing of Remicade for Rheumatoid Arthritis in Austria Monitored Over 9 Infusions (Study P03756)(COMPLETED)Real Life Dosing Regimen of Remicade in Austria, Monitored Over 9 Consecutive Infusions in Rheumatoid Arthritis TherapyRheumatoid ArthritisBiological: InfliximabMerck Sharp & Dohme Corp.Centocor, Inc.CompletedN/AN/AAll516N/AAustria