Citalopram ( DrugBank: Citalopram )


7 diseases
告示番号疾患名(ページ内リンク)臨床試験数
6パーキンソン病2
8ハンチントン病1
13多発性硬化症/視神経脊髄炎1
18脊髄小脳変性症(多系統萎縮症を除く。)1
46悪性関節リウマチ1
98好酸球性消化管疾患1
127前頭側頭葉変性症1

6. パーキンソン病


臨床試験数 : 2,298 薬物数 : 2,218 - (DrugBank : 350) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 202
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04497168
(ClinicalTrials.gov)
April 1, 202129/7/2020Citalopram as a Posterior Cortical Protective Therapy in Parkinson DiseaseCitalopram as a Posterior Cortical Protective Therapy in Parkinson DiseaseParkinson DiseaseDrug: Citalopram 20mg;Drug: PlaceboUniversity of MichiganNational Institute on Aging (NIA)Recruiting65 YearsN/AAll58Phase 2United States
2NCT04590612
(ClinicalTrials.gov)
January 202117/9/2020Improving Quality of Life in Early Parkinson's DiseaseThe Effects of Mood Symptoms Treatment on Quality of Life and Motor Function in de Novo Parkinson's Disease PatientsParkinson Disease;DepressionDrug: Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet;Drug: CitalopramWestern University, CanadaNULLNot yet recruiting50 Years80 YearsAll30N/ANULL

8. ハンチントン病


臨床試験数 : 229 薬物数 : 197 - (DrugBank : 60) / 標的遺伝子数 : 84 - 標的パスウェイ数 : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00271596
(ClinicalTrials.gov)
November 200530/12/2005Citalopram to Enhance Cognition in HDA Randomized, Placebo-Controlled Pilot Study in Huntington's Disease (CIT-HD)Huntington Disease;Chorea;Executive DysfunctionDrug: 20mg daily citalopram;Drug: PlaceboUniversity of IowaNational Institute of Neurological Disorders and Stroke (NINDS);Cure Huntington's Disease Initiative (CHDI);University of Rochester;Mayo ClinicCompleted18 Years75 YearsAll33Phase 2United States

13. 多発性硬化症/視神経脊髄炎


臨床試験数 : 3,342 薬物数 : 2,380 - (DrugBank : 407) / 標的遺伝子数 : 266 - 標的パスウェイ数 : 240
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01436643
(ClinicalTrials.gov)
November 201116/9/2011Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With DepressionA 21-week, Multicenter, Open Label Study to Evaluate the Safety and Tolerability Profile of the Combination of a SSRI or SNRI Antidepressive Therapy With Oral Fingolimod in the Treatment of RRMS Patients With Mild to Moderate DepressionDepression;Relapsing-remitting Multiple SclerosisDrug: Venlafaxine;Drug: Fluoxetine;Drug: Citalopram;Drug: FingolimodNovartis PharmaceuticalsNULLTerminated18 Years65 YearsAll54Phase 4Germany

18. 脊髄小脳変性症(多系統萎縮症を除く。)


臨床試験数 : 71 薬物数 : 101 - (DrugBank : 30) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 65
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01716221
(ClinicalTrials.gov)
October 201225/10/2012An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaAn Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaFriedreich AtaxiaDrug: bupropion & Citalopram;Drug: Bupropion & Placebo;Drug: Placebo & Citalopram;Drug: Placebo & PlaceboUniversity of Colorado, DenverNULLCompletedN/AN/AFemale1Phase 4NULL

46. 悪性関節リウマチ


臨床試験数 : 4,325 薬物数 : 2,681 - (DrugBank : 417) / 標的遺伝子数 : 185 - 標的パスウェイ数 : 223
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01154647
(ClinicalTrials.gov)
September 201028/6/2010Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity SyndromesUnraveling Impaired Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes: a Series of Experiments Targeting Brain NeurotransmissionFatigue Syndrome, Chronic;Fibromyalgia;Arthritis, RheumatoidDrug: citalopram;Drug: 1 ml 0.9 % NaClVrije Universiteit BrusselResearch Foundation Flanders;Universiteit Antwerpen;University Hospital, Antwerp;Artesis University College, AntwerpNot yet recruiting18 Years65 YearsFemale70N/ABelgium

98. 好酸球性消化管疾患


臨床試験数 : 171 薬物数 : 189 - (DrugBank : 47) / 標的遺伝子数 : 41 - 標的パスウェイ数 : 140
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2021-002288-24-NL
(EUCTR)
10/08/202127/07/2021Effect of citalopram on chest pain in patients with chest pain of unkown originEffect of citalopram on chest pain in patients with functional chest pain - Ci-FCP Chest pain can be divided in cardiac or non-cardiac chest pain (NCCP). To establish the diagnosis NCCP, acute coronary disease has to be ruled out first. NCCP can be caused by functional chest pain (FCP). NCCP in the absence of musculoskeletal abnormalities, major esophageal motor disorders, gastroesophageal reflux or eosinophilic esophagitis is called FCP.;Therapeutic area: Diseases [C] - Symptoms and general pathology [C23]Trade Name: Citalopram
Product Name: Citalopram
Amsterdam UMCNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
52Phase 4Netherlands

127. 前頭側頭葉変性症


臨床試験数 : 89 薬物数 : 105 - (DrugBank : 33) / 標的遺伝子数 : 40 - 標的パスウェイ数 : 117
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00376051
(ClinicalTrials.gov)
September 200613/9/2006Serotonergic Function and Behavioural and Psychological Symptoms of Frontotemporal DementiaSerotonergic Function and Behavioural and Psychological Symptoms of Frontotemporal DementiaFrontotemporal DementiaDrug: CitalopramSunnybrook Health Sciences CentreAlzheimer Society of CanadaCompleted18 YearsN/AAll22Phase 4Canada