Tocilizumab plus methotrexate ( DrugBank: Methotrexate, Tocilizumab )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
46悪性関節リウマチ4

46. 悪性関節リウマチ


臨床試験数 : 4,325 薬物数 : 2,681 - (DrugBank : 417) / 標的遺伝子数 : 185 - 標的パスウェイ数 : 223
No.TrialIDDate_
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agemin
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agemax
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PhaseCountries
1JPRN-UMIN000015616
2014/11/0410/11/2014Biologic MateR clinical performance test for ADA and TCZ Efficacy prediction rheumatoid arthritisAdalimumab plus Methotrexate
Tocilizumab plus Methotrexate
Biologic Mate Study GroupNULLComplete: follow-up complete20years-old75years-oldMale and Female300Not selectedJapan
2JPRN-UMIN000002744
2009/11/0110/11/2009Success of tocilizumab in RA patients with remission induction and sustained efficacy after discontinuation rheumatoid arthritistocilizumab plus methotrexate
tocilizumab
Keio UniversityNULLComplete: follow-up complete20years-old75years-oldMale and Female300Not selectedJapan
3NCT01120366
(ClinicalTrials.gov)
October 20096/5/2010Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After DiscontinuationSuccess of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After DiscontinuationRheumatoid ArthritisDrug: Tocilizumab plus methotrexate;Drug: TocilizumabSURPRISE Study GroupNULLCompleted20 Years75 YearsBoth233Phase 4Japan
4NCT00754572
(ClinicalTrials.gov)
February 200917/9/2008A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid ArthritisA Single-arm, Open-label Study of the Safety and Reduction of Signs and Symptoms During Treatment With Tocilizumab in Combination With Methotrexate, in Patients With Moderate to Severe Active Rheumatoid ArthritisRheumatoid ArthritisDrug: tocilizumab [RoActemra/Actemra];Drug: methotrexateHoffmann-La RocheNULLCompleted18 YearsN/AAll418Phase 3Argentina;Brazil;Chile;Colombia;Costa Rica;Ecuador;Mexico;Peru;Uruguay;Venezuela