:Acetazolamide    (DrugBank: Acetazolamide)

6 diseases
告示番号疾患名(ページ内リンク)臨床試験数
13多発性硬化症/視神経脊髄炎1
90網膜色素変性症1
115遺伝性周期性四肢麻痺1
155ランドウ・クレフナー症候群1
225先天性腎性尿崩症1
230肺胞低換気症候群1

13. 多発性硬化症/視神経脊髄炎 [臨床試験数:3,050,薬物数:2,147(DrugBank:348),標的遺伝子数:244,標的パスウェイ数:228
Searched query = "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3,050 trial found
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1NCT02466074August 17, 20163/6/2015Augmenting Cerebral Blood Flow to Treat Established Multiple SclerosisAugmenting Cerebral Blood Flow to Treat Established Multiple SclerosisMultiple SclerosisDrug: Acetazolamide;Drug: PlaceboThe University of Texas Health Science Center, HoustonNULLActive, not recruiting18 Years55 YearsAll60Phase 2United States

90. 網膜色素変性症 [臨床試験数:103,薬物数:158(DrugBank:42),標的遺伝子数:52,標的パスウェイ数:107
Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 103 trial found
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1JPRN-UMIN0000226862016/07/0101/07/2016The Clinical Efficacy of Carbonic Anhydrase Inhibitors and Steroids in the Management of Cystoid Macular Edema in Patients with Retinitis PigmentosaThe Clinical Efficacy of Carbonic Anhydrase Inhibitors and Steroids in the Management of Cystoid Macular Edema in Patients with Retinitis Pigmentosa - The Clinical Efficacy in the Management of Cystoid Macular Edema in Patients with Retinitis Pigmentosa retinitis pigmentosa1% dorzolamide eye drop three times daily in each eye
0.1% betamethasone sodium phosphate eye drop three times daily in each eye
oral 250mg acetazolamide two tablets daily
40mg triamcinolone acetonide into the sub-Tenon capsule
Kyushu University HospitalNULLComplete: follow-up complete20years-oldNot applicableMale and Female40Not appl1cableJapan

115. 遺伝性周期性四肢麻痺 [臨床試験数:1,薬物数:2(DrugBank:2),標的遺伝子数:13,標的パスウェイ数:7
Searched query = "Hereditary periodic paralysis", "Hereditary Hypokalemic Periodic Paralysis", "Andersen-Tawil syndrome", "Hereditary Hyperkalemic Periodic Paralysis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 1 trial found
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1NCT00839501December 20085/2/2009Effect of Potassium and Acetazolamide on People With Andersen-Tawil SyndromeTherapeutic Trial of Potassium and Acetazolamide in Andersen-Tawil SyndromeAndersen-Tawil SyndromeDietary Supplement: Potassium;Drug: AcetazolamideUniversity of RochesterOffice of Rare Diseases (ORD);Rare Diseases Clinical Research Network;National Institute of Neurological Disorders and Stroke (NINDS)Terminated10 YearsN/ABoth3Phase 1United States;United Kingdom

155. ランドウ・クレフナー症候群 [臨床試験数:1,薬物数:2(DrugBank:2),標的遺伝子数:29,標的パスウェイ数:14
Searched query = "Acquired aphasia with convulsive disorder", "Landau-Kleffner syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 1 trial found
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1NCT02904265September 201613/9/2016Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner SyndromeNon-inferiority Prospective Randomized Trial of Acetazolamide Versus Diazepam in Patients With Continuous Spike and Wave in Sleep (CSWS)/Landau Kleffner Syndrome (LKS)Landau-Kleffner Syndrome;Status Epilepticus, ElectrographicDrug: Diazepam;Drug: AcetazolamideMayo ClinicNULLTerminated3 Years12 YearsAll3Phase 2/Phase 3United States

225. 先天性腎性尿崩症 [臨床試験数:12,薬物数:45(DrugBank:17),標的遺伝子数:30,標的パスウェイ数:63
Searched query = "Congenital nephrogenic diabetes insipidus", "Hereditary nephrogenic diabetes insipidus", "Nephrogenic diabetes insipidus"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 12 trial found
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1EUCTR2011-005970-41-NL27/02/201208/02/2012The effect of the drug acetazolamide on excessive urine production due to a diminished concentrating ability of the kidney as a result of the use of lithium in patients with an affective disorder: a pilot studyThe effect of acetazolamide on lithium-induced nephrogenic diabetes insipidus in patients with an affective disorder: a pilot study lithium-induced nephrogenic diabetes insipidus
MedDRA version: 14.1Level: LLTClassification code 10012600Term: Diabetes insipidus nephrogenicSystem Organ Class: 10038359 - Renal and urinary disorders
MedDRA version: 14.1Level: LLTClassification code 10050501Term: Lithium toxicitySystem Organ Class: 10022117 - Injury, poisoning and procedural complications;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]
Trade Name: Acetazolamide Sandoz 250
Other descriptive name: ACETAZOLAMIDE
Radboud University Nijmegen Medical CentreNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Netherlands

230. 肺胞低換気症候群 [臨床試験数:8,薬物数:11(DrugBank:5),標的遺伝子数:18,標的パスウェイ数:27
Searched query = "Alveolar hypoventilation syndrome", "AHS", "Hypoventilation syndrome", "OHS", "CCHS", "Idiopathic central alveolar hypoventilation", "ICAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 8 trial found
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1NCT01499485November 201120/12/2011Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic AlkalosisDrug: Acetazolamide;Drug: PlaceboHospital Son LlatzerNULLCompleted18 YearsN/ABoth140Phase 3Spain