Amoxicillin    (DrugBank: Amoxicillin)

7 diseases
告示番号疾患名(ページ内リンク)臨床試験数
6パーキンソン病1
46悪性関節リウマチ1
63特発性血小板減少性紫斑病2
96クローン病2
97潰瘍性大腸炎10
222一次性ネフローゼ症候群1
299嚢胞性線維症3

6. パーキンソン病 [臨床試験数:2,123,薬物数:2,046(DrugBank:324),標的遺伝子数:183,標的パスウェイ数:198
Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2,123 trial found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
1NCT00664209
(ClinicalTrials.gov)
January 200821/4/2008Treating H. Pylori in Parkinson's Patients With Motor FluctuationsHelicobacter Pylori Eradication and Motor Fluctuations in Parkinson's DiseaseParkinson's Disease;Helicobacter Infections;Motor FluctuationsDrug: clartihromycin, amoxicillin, and omeprazole;Drug: placeboUniversity of California, Los AngelesMichael J. Fox Foundation for Parkinson's ResearchTerminatedN/AN/AMale64Phase 3United States

46. 悪性関節リウマチ [臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 4,183 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
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Inclusion_
agemin
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PhaseCountries
1EUCTR2017-003259-40-ES
(EUCTR)
04/01/201824/10/2017Periodontitis treatment in patients with reumatoid arthritis and high clinical activity in the. Randomized clinical trial.Periodontitis treatment in patients with reumatoid arthritis and high clinical activity in the. Randomized clinical trial. Patients with rheumatoid arthritis with high clinical activity and chronical peirodontitis moderate-severe.
MedDRA version: 20.0;Level: PT;Classification code 10039073;Term: Rheumatoid arthritis;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Product Name: amoxicilina
INN or Proposed INN: AMOXICILLIN
Product Name: metronidazol
INN or Proposed INN: METRONIDAZOLE
Other descriptive name: metronidazol
Dra Beatriz Lozano-Hospital Universitario de CanariasNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
120Phase 4Spain

63. 特発性血小板減少性紫斑病 [臨床試験数:311,薬物数:185(DrugBank:39),標的遺伝子数:43,標的パスウェイ数:132
Searched query = "Idiopathic thrombocytopenic purpura", "Primary immune thrombocytopenia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 311 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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agemin
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PhaseCountries
1JPRN-JapicCTI-153003
01/9/2015Drug use surveillance of Takecab for Supplement to Helicobacter pylori eradicationDrug use surveillance of Takecab tablets Supplement to Helicobacter pylori eradication The following diseases in patients for whom H. pylori will be eradicated with triple therapy: Gastric ulcer, duodenal ulcer, gastric mucosa-associated lymphoid tissue (MALT) lymphoma, idiopathic thrombocytopenic purpura, stomach following endoscopic treatment of early gastric cancer, or H. pylori gastritisIntervention name : Takecab tablets + amoxicillin + clarithromycin (first-line eradication) Takecab tablets + amoxicillin + metronidazole (second-line eradication)
Dosage And administration of the intervention : For adults, the following three-drug regimen will be administered orally at the same time twice daily for 7 days: 20 mg dose of vonoprazan, 750 mg (potency) dose of amoxicillin hydrate, and 200 mg (potency) dose of clarithromycin. The dose of clarithromycin may be increased as clinically warranted. However, dosage should not exceed 400 mg (potency)/dose twice daily. If H. pylori eradication with a three-drug regimen comprising vonoprazan or proton pump inhibitor + amoxicillin hydrate + clarithromycin has been unsuccessful, as an alternative treatment, the following three drugs will be administered orally twice daily for 7 days to adults: 20 mg dose of vonoprazan, 750 mg (potency) dose of amoxicillin hydrate, and 250 mg dose of metronidazole. Participants will receive interventions as part of routine medical care.
Control intervention name : null
TAKEDA PHARMACEUTICAL COMPANY LTD.NULLBOTH500NANULL
2NCT03219723
(ClinicalTrials.gov)
September 1, 20159/7/2017Drug Use Surveillance of Takecab for Supplement to Helicobacter Pylori EradicationDrug Use Surveillance of Takecab Tablets Supplement to Helicobacter Pylori EradicationGastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and OtherDrug: Vonoprazan;Drug: Amoxicillin hydrate;Drug: Clarithromycin;Drug: MetronidazoleTakedaNULLCompletedN/AN/AAll560Japan

96. クローン病 [臨床試験数:2,209,薬物数:1,276(DrugBank:240),標的遺伝子数:166,標的パスウェイ数:210
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 2,209 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
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gender
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size
PhaseCountries
1JPRN-jRCTs031180415
01/02/201722/03/2019A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel diseaseSingle center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults).
FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site.
A-FMT arm : Patient undergoes FMT two days after AFM therapy.
Ishikawa DaiNULLRecruiting>= 6age oldNot applicableBoth120N/AJapan
2JPRN-UMIN000025846
2017/02/0101/02/2017A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease ulcerative colitis, Crohn's diseaseAdministration of the fecal material from healthy donors to patients after taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeksJuntendo university school of medicineDepartment of gastroenterologyNULLRecruiting16years-oldNot applicableMale and Female60Not selectedJapan

97. 潰瘍性大腸炎 [臨床試験数:2,269,薬物数:1,331(DrugBank:241),標的遺伝子数:114,標的パスウェイ数:181
Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
10 / 2,269 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Inclusion_
agemin
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agemax
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gender
Target_
size
PhaseCountries
1NCT03986996
(ClinicalTrials.gov)
July 20194/6/2019Antimicrobial Therapy for Ulcerative Colitis (UC)Antimicrobial Therapy for Ulcerative Colitis : Evaluation of Two Antibiotic Combinations for Refractory Ulcerative ColitisUlcerative ColitisDrug: amoxicillin, metronidazole and tetracycline;Drug: amoxicillin and tetracyclineWolfson Medical CenterNULLNot yet recruiting13 Years60 YearsAll40Phase 2Israel
2JPRN-jRCTs031180415
01/02/201722/03/2019A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel diseaseSingle center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults).
FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site.
A-FMT arm : Patient undergoes FMT two days after AFM therapy.
Ishikawa DaiNULLRecruiting>= 6age oldNot applicableBoth120N/AJapan
3JPRN-UMIN000025846
2017/02/0101/02/2017A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease ulcerative colitis, Crohn's diseaseAdministration of the fecal material from healthy donors to patients after taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeksJuntendo university school of medicineDepartment of gastroenterologyNULLRecruiting16years-oldNot applicableMale and Female60Not selectedJapan
4JPRN-UMIN000024520
2016/12/1522/10/2016Exploratory study of antibiotics combination therapy for moderate to severe ulcerative colitis ulcerative colitisplacebo
metronidazole
metronidazole,amoxicillin
metronidazole,amoxicillin,tetracycline
Hokkaido University HospitalNULLComplete: follow-up complete16years-old80years-oldMale and Female212Not selectedJapan
5JPRN-UMIN000026485
2016/08/0110/03/2017Research on the Efficacy of Fecal Microbiota Transplantation and Microbiota in Japanese Children with Ulcerative Colitis. ulcerative colitisFecal Microbiota Transplantation(on Day1, 2 and 3, week 2, 3 and 5) after antibiotic pretreatment using amoxicillin 40mg/kg/day, fosfomycin 100mg/kg/day and metronidazole 16mg/kg/day.National Center for Child Health and Development10Probiotics Research Laboratory, Juntendo University Graduate School of Medicine, Tokyo, Japan. Yakult Central Institute, Tokyo, JapanRecruiting2years-old18years-oldMale and Female12Not selectedJapan
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
6JPRN-UMIN000018642
2015/08/1211/08/2015A trial of fecal microbiota transplantation and / or antibiotics therapy for ulcerative colitis ulcerative colitisAntibiotics therapy:Taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeks.
FMT:Administration of the fecal material from healthy donors to patients.
Juntendo university school of medicine Department of gastroenterologyNULLRecruiting6years-oldNot applicableMale and Female50Not selectedJapan
7JPRN-UMIN000017844
2015/06/2222/06/2015Antibiotic combination therapy for ulcerative colitis ulcerative colitisamoxicillin, tetracycline, and metronidazoleShiga University of Medical ScienceNULLComplete: follow-up complete20years-old80years-oldMale and Female20Not selectedJapan
8JPRN-UMIN000014152
2014/06/0404/06/2014A trial of a combination therapy of fecal microbiota transplantation and antibiotics or simple fecal microbiota therapy for ulcerative colitis ulcerative colitisAdministration of the fecal material from healthy donors to patients after taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeksJuntendo university school of medicine Department of gastroenterologyNULLRecruiting20years-oldNot applicableMale and Female30Not selectedJapan
9JPRN-UMIN000009811
2013/01/2321/01/2013Comparison of randomized trials of antibiotic combination therapies for patients with ulcerative colitisComparison of randomized trials of antibiotic combination therapies for patients with ulcerative colitis - Antibiotics trials for ulcerative colitis Ulcerative colitisOne group is to receive two-week combination therapy consisting of amoxicillin (Sawacillin) 500 mg t.i.d, tetracycline (Acromycin) 500 mg t.i.d, and metronidazole (Flagyl) 250 mg t.i.d. with an inhibitor of gastric acid secretion. Patients are to be followed for 3 months (first endpoint).
Another group will receive two week combination therapy consisting of amoxicillin (Sawacillin) 500 mg t.i.d, fosfomycin (Fosmicin) 1000mg t.i.d, and metrozole (Flagyl) 250 mg t.i.d, with an inhibitor of gastric acid secretion. Patients are to be followed for 3 months.
Division of General Medicine, Department of Internal Medicine, Nihon University School of MedicineNULLComplete: follow-up complete16years-old75years-oldMale and Female40Phase 3Japan
10JPRN-C000000078
2003/10/0126/08/2005Antibiotic Combination Therapy in Patients with Active Refractory Ulcerative Colitis: A Prospective Randomized Placebo-controlled Multicenter Study Ulcerative ColitisPatients in the treatment group receive an antibiotic combination consisting of amoxicillin 500mg tid, tetracycline 500mg tid, and metronidazole 250mg tid for two weeks.
patients in the control group recieve three kinds of placebo contained sugar.
Japan UC Antibiotics-therapy Study Group(JUCASG)Nihon University,Iwate Medical University, Kyoto Central HospitalYamagata Central HospitalOita University, Tokyo Medical UniversityToyama Medical & Pharmaceutical University, Showa UniversityComplete: follow-up complete15years-old70years-oldMale and Female210Phase 2Japan

222. 一次性ネフローゼ症候群 [臨床試験数:234,薬物数:241(DrugBank:78),標的遺伝子数:59,標的パスウェイ数:185
Searched query = "Primary nephrotic syndrome", "Minimal change nephrotic syndrome", "MCNS", "Membranous nephropathy", "Focal segmental glomerulosclerosis", "FSGS", "Membranoproliferative glomerulonephritis", "MPGN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 234 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Inclusion_
agemin
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gender
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size
PhaseCountries
1NCT00983034
(ClinicalTrials.gov)
March 200621/9/2009The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous NephropathyProspective Study of the Effects of Helicobacter Pylori Eradication on Renal Functions and Proteinuria in Patients With Membranous NephropathyNephrotic Syndrome;Glomerulonephritis;Membranous NephropathyDrug: lansoprazole, amoxicillin, clarithromycinIstanbul UniversityNULLCompleted18 Years70 YearsBoth70N/ATurkey

299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 1,592 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
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gender
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PhaseCountries
1EUCTR2019-003501-10-NO
(EUCTR)
29/05/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a phase 4 multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a phase 4 multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]Trade Name: Amoxicillin
Product Name: Amoxicillin
INN or Proposed INN: AMOXICILLIN
Trade Name: Amoxicillin and Clavulanic acid
Product Name: Augmentin
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
Trade Name: Heracillin
Product Name: Heracillin
INN or Proposed INN: FLUCLOXACILLIN
Trade Name: Dicloxacillin
Product Name: Dicloxacillin
INN or Proposed INN: DICLOXACILLIN
Trade Name: Trimethoprim and Sulfamethoxazole
Product Name: Bactrim
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: SULFAMETHOXAZOLE
Trade Name: Clarithromycin
Product Name: Klacid
INN or Proposed INN: Klacid
Other descriptive name: CLARITHROMYCIN
Trade Name: Rifampicin
Product Name: Rimactan
INN or Proposed INN: RIFAMPICIN
Trade Name: Doxycycline
Product Name: Doxycyclin
INN or Proposed INN: DOXYCYCLINE
Product Name: Fucidin Tablets
INN or Proposed INN: Fusidin
Other descriptive name: FUSIDIC ACID
Trade Name: Ciprofloxacin
Product Name: Ciprofloxacin
INN or Proposed INN: Ciproxin
Other descriptive name: CIPROFLOXACIN
Trade Name: Linez
Vãstre Gõtalandsregionen, SwedenNULLNAFemale: yes
Male: yes
100Phase 4Denmark;Norway;Sweden
2EUCTR2019-003501-10-SE
(EUCTR)
07/04/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: FLUCLOXACILLIN
INN or Proposed INN: DICLOXACILLIN
INN or Proposed INN: SULFAMETHOXAZOLE
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: Clarithromycin
Other descriptive name: CLARITHROMYCIN
INN or Proposed INN: RIFAMPICIN
INN or Proposed INN: DOXYCYCLINE
INN or Proposed INN: Fusidic acid
Other descriptive name: FUSIDIC ACID
INN or Proposed INN: Ciprofloxacin
Other descriptive name: CIPROFLOXACIN
INN or Proposed INN: Linezolid
Other descriptive name: LINEZOLID
INN or Proposed INN: CLINDAMYCIN
Other descriptive name: CLINDAMYCIN
INN or Proposed INN: Cefuroxim
Other descriptive name: CEFUROXIME
INN or Proposed INN: CEFALEXIN
Västra GötalandsregionenNULLNAFemale: yes
Male: yes
100Phase 4Sweden
3EUCTR2019-003501-10-DK
(EUCTR)
22/04/2020Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study.Use of repeated Multiple Breath Washout to detect and treat pulmonary exacerbation in children with Cystic Fibrosis, a multicenter randomized controlled study. - MBWtodetectPEXinCF Cystic fibrosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: CLAVULANIC ACID
INN or Proposed INN: AMOXICILLIN
INN or Proposed INN: FLUCLOXACILLIN
INN or Proposed INN: DICLOXACILLIN
INN or Proposed INN: SULFAMETHOXAZOLE
INN or Proposed INN: Trimetoprim
Other descriptive name: TRIMETHOPRIM
INN or Proposed INN: Clarithromycin
Other descriptive name: CLARITHROMYCIN
INN or Proposed INN: RIFAMPICIN
INN or Proposed INN: DOXYCYCLINE
INN or Proposed INN: Fusidic acid
Other descriptive name: FUSIDIC ACID
INN or Proposed INN: Ciprofloxacin
Other descriptive name: CIPROFLOXACIN
INN or Proposed INN: Linezolid
Other descriptive name: LINEZOLID
INN or Proposed INN: CLINDAMYCIN
Other descriptive name: CLINDAMYCIN
INN or Proposed INN: Cefuroxim
Other descriptive name: CEFUROXIME
INN or Proposed INN: CEFALEXIN
Västra GötalandsregionenNULLNAFemale: yes
Male: yes
100Phase 4Denmark;Sweden