Gold    (DrugBank: Gold)

38 diseases
告示番号疾患名(ページ内リンク)臨床試験数
2筋萎縮性側索硬化症3
5進行性核上性麻痺1
6パーキンソン病14
13多発性硬化症/視神経脊髄炎5
17多系統萎縮症2
34神経線維腫症2
46悪性関節リウマチ6
49全身性エリテマトーデス1
50皮膚筋炎/多発性筋炎2
53シェーグレン症候群1
65原発性免疫不全症候群1
68黄色靱帯骨化症1
76下垂体性ゴナドトロピン分泌亢進症2
84サルコイドーシス2
86肺動脈性肺高血圧症5
91バッド・キアリ症候群1
93原発性胆汁性胆管炎2
95自己免疫性肝炎1
96クローン病4
97潰瘍性大腸炎2
98好酸球性消化管疾患1
113筋ジストロフィー1
158結節性硬化症1
162類天疱瘡(後天性表皮水疱症を含む。)1
171ウィルソン病2
218アルポート症候群1
222一次性ネフローゼ症候群3
224紫斑病性腎炎1
227オスラー病1
230肺胞低換気症候群1
271強直性脊椎炎1
291ヒルシュスプルング病(全結腸型又は小腸型)1
294先天性横隔膜ヘルニア1
296胆道閉鎖症5
298遺伝性膵炎1
299嚢胞性線維症1
310先天異常症候群1
318シトリン欠損症 1

2. 筋萎縮性側索硬化症 [臨床試験数:508,薬物数:530(DrugBank:146),標的遺伝子数:170,標的パスウェイ数:221
Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 508 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1NCT03843710
(ClinicalTrials.gov)
April 30, 202114/2/201931P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Amyotrophic Lateral Sclerosis (REPAIR-ALS)A Phase 2, Pilot Open Label, Sequential Group, Investigator Blinded Study of Magnetic Resonance Spectroscopy (31P-MRS) to Assess the Effects of CNM-Au8 for the Bioenergetic Improvement of Impaired Neuronal Redox State in Amyotrophic Lateral SclerosisAmyotrophic Lateral SclerosisDrug: Gold NanocrystalsClene NanomedicineUniversity of Texas Southwestern Medical CenterNot yet recruiting35 Years75 YearsAll24Phase 2United States
2ChiCTR1900024520
2019-07-222019-07-13Split-hand index calculated by F-wave test apply to the diagnosis of amyotrophic lateral sclerosisSplit-hand index calculated by F-wave test apply to the diagnosis of amyotrophic lateral sclerosis Amyotrophic lateral sclerosisGold Standard:Clinical outcome meet the Awaji-Shima Criteria 2008;Index test:Split-hand index calculated by F-wave test;Peking Union Medical College HospitaNULLRecruiting1880BothTarget condition:300;Difficult condition:50N/AChina
3NCT03690791
(ClinicalTrials.gov)
January 9, 201913/9/2018Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone DiseaseA Randomised, Double-blind, Single-centre Study on the Safety, Tolerability and Efficacy of Cannabis Based Medicine Extract (MediCabilis CBD Oil) in Slowing the Disease Progression in Amyotrophic Lateral Sclerosis or Motor Neurone Disease PatientsAmyotrophic Lateral Sclerosis;Motor Neuron DiseaseDrug: MediCabilis CBD Oil;Drug: Placebo OilGold Coast Hospital and Health ServiceBOD AustraliaRecruiting25 Years80 YearsAll30Phase 3Australia

5. 進行性核上性麻痺 [臨床試験数:82,薬物数:107(DrugBank:36),標的遺伝子数:60,標的パスウェイ数:90
Searched query = "Progressive supranuclear palsy", "PSP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 82 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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agemin
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agemax
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PhaseCountries
1ChiCTR2000030512
2019-05-132020-03-05Clinical study of [18F]-APN-1607([18F]-PM-PBB3) PET on tau tangles in the brain of progressive supranuclear palsyClinical study of [18F]-APN-1607([18F]-PM-PBB3) PET on tau tangles in the brain of progressive supranuclear palsy progressive supranuclear palsyGold Standard:clinical diagnosis of progressive supranuclear palsy the movement disorder society criteria in 2017.(Mov Disord. 2017 Jun;32(6):853-864. doi: 10.1002/mds.26987. Epub 2017 May 3.).;Index test:Standard uptake value ratio of [18F]-APN-1607([18F]-PM-PBB3);Huashan Hospital, Fudan UniversityNULLRecruiting4580BothTarget condition:26;Difficult condition:0China

6. パーキンソン病 [臨床試験数:2,123,薬物数:2,046(DrugBank:324),標的遺伝子数:183,標的パスウェイ数:198
Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
14 / 2,123 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
Recruitment_
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agemin
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agemax
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PhaseCountries
1ChiCTR2000038937
2020-11-012020-10-10Clinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis multimodal imagingClinical study of early diagnosis of Parkinson's disease based on substantia nigra-striatal axis multimodal imaging Parkinson's diseaseGold Standard:Clinical diagnosis by experienced movement disorder specialists after 2 years of follow-up.;Index test:Including traditional imaging feature algorithms (SUVR value, total cortical volume, bilateral cortical surface area, cortical thickness, etc.), high-dimensional imaging omics feature algorithms (energy entropy, gray-level co-occurrence matrix, and mutual information, etc.), and brain connection group Learning feature algorithm.;Huashan Hospital, Fudan UniversityNULLRecruiting4580BothTarget condition:105;Difficult condition:0China
2ChiCTR2000037856
2020-10-012020-09-02Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA)Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA) Parkinson's DiseaseGold Standard:DAT-PET and 18F-FDG PET ;Index test:a-synuclein protein misfolding cyclic amplification;Huashan Hospital Affiliated to Fudan UniversityNULLRecruiting5075BothTarget condition:150;Difficult condition:76China
3ChiCTR2000037239
2020-10-012020-08-27Construction and application of a diagnostic marker for Parkinson's disease based on gut microbiomicsConstruction and application of a diagnostic marker for Parkinson's disease based on gut microbiomics Parkinson's diseaseGold Standard:All patients satisfied the United Kingdom Parkinson's Disease Society Brain Bank criteria;Index test:Microbial gene detection chip;Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNULLRecruiting5580BothTarget condition:500;Difficult condition:600China
4ChiCTR2000036137
2020-10-012020-08-21Clinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiation of primary Parkinson's diseaseClinical study of 18F-FDG combined with 18F-AV-133 PET/CT imaging in the diagnosis and differentiation of primary Parkinson's disease Parkinson’s diseaseGold Standard:UK Parkinson's disease Society Brain Bank Clinical Diagnosis Criteria;Index test:18F-FDG combined with 18F-AV-133 PET/CT imaging;Renji Hospital (South Court), School of Medicine, Shanghai Jiao Tong UniversityNULLPendingBothTarget condition:50;Difficult condition:0China
5ChiCTR2000036006
2020-10-012020-08-21The applications of multi- MRI in early diagnosis of Parkinson's Disease based on deep learningThe applications of multi- MRI in early diagnosis of Parkinson's Disease based on deep learning Parkinson's diseaseGold Standard:MDS clinical diagnostic criteria for Parkinson’s disease;Index test:multimodal MRI features in locus coeruleus and substantia nigra;Zhongshan Hospital, Fudan UniversityNULLPending1885BothTarget condition:400;Difficult condition:0China
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
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agemax
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PhaseCountries
6ChiCTR2000032616
2020-05-302020-05-04Assistant diagnosis machinery system development based on speech and movement sensitive device for Parkinson's diseaseParkinson's disease, Assistant diagnosis machinery system, speech, movement sensitive device Parkinson's diseaseGold Standard:clinical outcome meet 2015 MDS-probable PD criteria;Index test:Acoustic receptive and analysis device,Wearable movement sensor;Shanghai Jiao Tong University School of Medicine affiliated Shanghai General HospitalNULLPendingBothTarget condition:20;Difficult condition:80China
7NCT03815916
(ClinicalTrials.gov)
December 19, 201918/1/201931P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's DiseaseA Phase 2, Pilot Open Label, Sequential Group, Investigator Blinded Study of Magnetic Resonance Spectroscopy (31P-MRS) to Assess the Effects of CNM-Au8 for the Bioenergetic Improvement of Impaired Neuronal Redox State in Parkinson's DiseaseParkinson's DiseaseDrug: Gold NanocrystalsClene NanomedicineUniversity of Texas Southwestern Medical CenterRecruiting30 Years80 YearsAll30Phase 2United States
8ChiCTR1900027306
2019-11-152019-11-08Application of optical coherence tomography and detection of a-synuclein in tears in the diagnosis of Parkinson's diseaseMorphological changes of retina in patients with Parkinson's disease and the role of a-synuclein in retinal damage Parkinson's diseaseGold Standard:British brain bank Parkinson's disease diagnostic criteria;Index test:Application of optical coherence tomography to observe the retinal structure of the macular area, optic disc area and the expression level of a-synuclein in tears in the diagnosis of Parkinson's disease.;The First Affiliated Hospital of Chengdu Medical CollegeNULLRecruitingBothTarget condition:85;Difficult condition:85China
9ChiCTR1800015757
2019-04-012018-04-18Value of 131I-MIBG salivary gland imaging in the early diagnosis of Parkinson's diseaseValue of 131I-MIBG salivary gland imaging in the early diagnosis of Parkinson's disease Parkinson's DiseaseGold Standard:PD diagnostic criteria made by MDS in 2016;Index test:reduced uptake in salivery gland and myocardium in I-131-MIBG scintigraphic imaging;Tongji hospital, Tongji UniversityNULLPendingBothTarget condition:30;Difficult condition:30China
10ChiCTR-DDD-16009569
2017-01-012016-10-24Differential diagnosis of primary Parkinson's disease by 18F-FDG combined with 11C-ß-CFT PET / CT imagingDifferential diagnosis of primary Parkinson's disease by 18F-FDG combined with 11C-ß-CFT PET / CT imaging Parkinson's DiseaseGold Standard:;Index test:;Renji hospital, School of Medicine, Shanghai Jiao Tong UniversityNULLPending2080BothTarget condition:0;Difficult condition:0China
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
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agemax
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gender
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size
PhaseCountries
11ChiCTR-DOC-16008645
2016-07-012016-06-15The study of radionuclide imaging and biomarkers in clinical diagnosis and treatment of Parkinson's diseaseThe study of radionuclide imaging and biomarkers in clinical diagnosis and treatment of Parkinson's disease Parkinson DiseaseGold Standard:;Index test:;101th Hospital of PLANULLPending1880BothTarget condition:0;Difficult condition:0NULL
12ChiCTR-DRD-16008778
2016-07-012016-07-04The study of Parkinson's disease imaging biomarkers based on MR with high resolution and multi modeThe study of Parkinson's disease imaging biomarkers based on MR with high resolution and multi mode Parkinson`s DiseaseGold Standard:;Index test:;Xiangyang Hospital, Hubei University of MedicineNULLRecruitingBothTarget condition:0;Difficult condition:0China
13ChiCTR-DOD-15006097
2015-03-182015-03-16The diagnostic value of olfactory-evoked potentials in Parkinson'sdiseaseThe diagnostic value of olfactory-evoked potentials in Parkinson'sdisease Parkinson's diseaseGold Standard:;Index test:;Guangdong General Hospital, Guangdong Academy of Medical SciencesNULLRecruiting5080BothTarget condition:0;Difficult condition:0China
14ChiCTR-DDD-17010794
2014-11-082017-03-05The study on early diagnosis of Parkinson 's disease by transcranial ultrasonographythe study on early diagnosis of Parkinson 's disease by transcranial ultrasonography Parkinson's DiseaseGold Standard:Diagnosis of Parkinson disease needs to meet 3 or more: unilateral onset;resting tremor;progressive course; long term asymmetry, the most obvious symptoms is the onset side; a good response to levodopa (70% ~ 100%); levodopa induced chorea; a reaction of levodopa lasts 5 years or more; clinical course last;Index test:Laboratory apparatus
As shown in Figure 1, The ultrasound equipment, Philips IE33-BOMJH1 color Doppler ultrasonography, Model IE-ELite, with 2-4MHz phased array probe (S5-1 probe) was used for TCS to examine SN in our study.
Transcranial ultrasound study
Ultrasonography through temporal window, alon;
Department of Neurology, Fujian Institute of Geriatrics, Fujian Medical University Union HospitalNULLCompleted3684BothTarget condition:135;Difficult condition:0China

13. 多発性硬化症/視神経脊髄炎 [臨床試験数:3,050,薬物数:2,147(DrugBank:348),標的遺伝子数:244,標的パスウェイ数:228
Searched query = "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 3,050 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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Status
Inclusion_
agemin
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agemax
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size
PhaseCountries
1ChiCTR2000034098
2020-07-012020-06-23A New Quantitative Method Used to Evaluate Cervical Spinal Cord Damage in Multiple Sclerosis: Diffusional Kurtosis Imaging ResearchA New Quantitative Method Used to Evaluate Cervical Spinal Cord Damage in Multiple Sclerosis: Diffusional Kurtosis Imaging Research Multiple SclerosisGold Standard:Conventional cervical MRI;Index test:Diffusional Kurtosis Imaging;The First Hospital of Jilin UniversityNULLPendingBothTarget condition:48;Difficult condition:0China
2NCT03993171
(ClinicalTrials.gov)
December 19, 201931/5/201931P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.A Phase 2, Open-Label, Sequential Group, Investigator Blinded Study of Magnetic Resonance Spectroscopy (31P-MRS) to Assess the Effects of CNM-Au8 for the Bioenergetic Improvement of Impaired Neuronal Redox State in Multiple Sclerosis.Relapsing Remitting Multiple SclerosisDrug: gold nanocrystalsClene NanomedicineUniversity of Texas Southwestern Medical CenterRecruiting18 Years55 YearsAll30Phase 2United States
3NCT03536559
(ClinicalTrials.gov)
November 23, 20182/5/2018Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple SclerosisA Phase 2, Randomized, DB-PC, Parallel Group Study for the Treatment of Visual Pathway Deficits In Chronic Optic Neuropathy to Assess the Efficacy, Safety, Tolerability and Pharmacokinetics of CNM-Au8 For Remyelination In Multiple SclerosisRelapsing Remitting Multiple Sclerosis;Optic Neuropathy;Optic; Neuritis, With DemyelinationDrug: CNM-Au8;Drug: PlaceboClene NanomedicineClene Australia Pty LtdRecruiting18 Years55 YearsAll150Phase 2United States;Australia;Canada
4ChiCTR-DND-17013749
2017-12-012017-12-07Application of 3.0 T MRI 3D sequences of CUBE-T2 FLAIR?DIR for brain lesions of childhood-onset multiple sclerosisApplication of 3.0 T MRI 3D sequences of CUBE-T2 FLAIR?DIR for brain lesions of childhood-onset multiple sclerosis childhood-onset multiple sclerosisGold Standard:CUBE-T2 FLAIR scanning;Index test:DIR scanning;Children's Hospital of Chongqing Medical UniversityNULLRecruitingBothTarget condition:80;Difficult condition:0China
5EUCTR2010-024017-31-IT
(EUCTR)
15/03/201108/02/2011A 6-month, Randomized, Active Comparator, Open-label, Multi-Center Study to Evaluate Patient OutComes, Safety and Tolerability of Fingolimod (FTY720) 0.5 mg/day in Patients with Relapsing Remitting Multiple Sclerosis who are candidates for MS therapy change from Previous Disease Modifying Therapy - GOLDENA 6-month, Randomized, Active Comparator, Open-label, Multi-Center Study to Evaluate Patient OutComes, Safety and Tolerability of Fingolimod (FTY720) 0.5 mg/day in Patients with Relapsing Remitting Multiple Sclerosis who are candidates for MS therapy change from Previous Disease Modifying Therapy - GOLDEN Relapsing Remitting Multiple Sclerosis
MedDRA version: 9.1;Level: LLT;Classification code 10063399
Product Name: FINGOLIMOD
Product Code: FTY720D
Trade Name: EXTAVIA
INN or Proposed INN: Interferon beta-1b
Trade Name: AVONEX
INN or Proposed INN: Interferon beta-1a
Trade Name: COPAXONE
INN or Proposed INN: Glatiramer acetate
NOVARTIS FARMANULLNot RecruitingFemale: yes
Male: yes
Italy

17. 多系統萎縮症 [臨床試験数:107,薬物数:153(DrugBank:48),標的遺伝子数:59,標的パスウェイ数:104
Searched query = "Multiple system atrophy", "MSA-C", "MSA-P", "Olivopontocerebellar atrophy", "OPCA", "Striatonigral degeneration", "Shy-Drager syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 107 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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agemin
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PhaseCountries
1ChiCTR2000033282
2020-06-012020-05-26Construction of cohort and prognosis prediction model of multiple system atrophyConstruction of cohort and prognosis prediction model of multiple system atrophy Multiple system atrophyGold Standard:Clinical outcomes.;Index test:Prognosis prediction model of multiple system atrophy;West China Hospital of Sichuan UniversityNULLRecruiting3075BothTarget condition:600;Difficult condition:0China
2ChiCTR-DPC-15005941
2015-03-012015-01-25Study for the diagnosis and differential diagnosis of multiple system atrophyStudy for the diagnosis and differential diagnosis of multiple system atrophy Multiple system atrophyGold Standard:electrophysiological techniques;Index test:brain MRI;Navy general hospitalNULLCompleted3080BothTarget condition:260;Difficult condition:0China

34. 神経線維腫症 [臨床試験数:120,薬物数:182(DrugBank:72),標的遺伝子数:84,標的パスウェイ数:194
Searched query = "Neurofibromatosis", "NF1", "von Recklinghausen disease", "NF2"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 120 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
Recruitment_
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Inclusion_
agemin
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PhaseCountries
1ChiCTR2000036770
2020-10-012020-08-25Establishment of prediction model of selumetinib therapy in the treatment of plexiform neurofibroma based on exosomes test from liquid biopsyEstablishment of prediction model of selumetinib therapy in the treatment of plexiform neurofibroma based on exosomes test from liquid biopsy Plexiform Neurofibromatosis type 1Gold Standard:Clinical outcomes;Index test:Prediction model of selumetinib therapy in the treatment of plexiform neurofibroma based on exosomes test from liquid biopsy;Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of MedicineNULLPending265BothTarget condition:32;Difficult condition:0China
2ChiCTR-DDD-16009551
2016-10-282016-10-23Comparative study of Sanger sequencing and specific panel high-throughput sequencing for detection of NF1 pathogenic mutations in Han ChineseComparative study of Sanger sequencing and specific panel high-throughput sequencing for detection of NF1 pathogenic mutations in Han Chinese neurofibromatosis;M95400/1Gold Standard:;Index test:;Shanghai 9th People's Hospital Affiliated to Shanghai Jiaotong University School of MedicineNULLRecruiting1045BothTarget condition:0;Difficult condition:0China

46. 悪性関節リウマチ [臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 4,183 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR1800018637
2018-09-262018-09-30Correlation between Human epididymis protein 4 and interstitial lung disease in patients with rheumatoid arthritisCorrelation between Human epididymis protein 4 and interstitial lung disease in patients with rheumatoid arthritis rheumatoid arthritisGold Standard:Clinical outcome, meet the 2010 ACR/EULAR rheumatoid arthritis classification criteria.;Index test:Human epididymis protein 4,anti-cyclic citrullinated peptide, creatinine, rheumatoid factor;Affiliated Hospital of North Sichuan Medical CollegeNULLRecruitingBothTarget condition:150;Difficult condition:100China
2ChiCTR-DDT-12002658
2012-12-012012-11-04Validation of early rheumatoid arthritis classification criteriaValidation of early rheumatoid arthritis classification criteria rheumatoid arthritisGold Standard:;Index test:;Peking University People's HospitalNULLCompleted16100BothTarget condition:0;Difficult condition:0China
3ChiCTR-DDT-12002268
2011-06-112012-06-11Early diagnosis of rheumatoid arthritisStudy on the clinical application of imaging in early rheumatoid rheumatoid arthritisGold Standard:;Index test:;Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical UniversityNULLCompleted1865BothTarget condition:0;Difficult condition:0China
4EUCTR2010-019514-24-CZ
(EUCTR)
21/04/201106/12/2010Study to determine the effects of different doses of Methotrexate (MTX) when taken with adalimumab in subjects with Early Rheumatoid Arthritis (RA)A Double-Blind, Randomized, Parallel-Arm, Multi-Center Study to Determine the Dose Response of Methotrexate (MTX) in Combination Therapy with Adalimumab in Subjects with Early Rheumatoid Arthritis. - CONCERTO Rheumatoid Arthritis.
MedDRA version: 14.1;Level: PT;Classification code 10039073;Term: Rheumatoid arthritis;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20]
Trade Name: Humira
INN or Proposed INN: ADALIMUMAB
Trade Name: MTX HEXAL Tablets
INN or Proposed INN: METHOTREXATE
Trade Name: MTX Goldshield Tablets
INN or Proposed INN: METHOTREXATE
AbbVie Deutschland GmbH & Co. KGNULLNot RecruitingFemale: yes
Male: yes
380United States;Czech Republic;Canada;Puerto Rico;Argentina;Spain;Belgium;Austria;Germany
5NCT00491933
(ClinicalTrials.gov)
June 200725/6/2007Quantiferon-TB Gold in the Assessment of Latent TB in Patients Candidate to Treatment or Treated With TNFa AntagonistsComparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in the Assessment of Latent Mycobacterium Tuberculosis Infection in Patients Candidate to Treatment or Treated With TNFa AntagonistsRheumatoid Arthritis;Spondylarthritis;TuberculosisProcedure: Quantiferon-TB Gold assay;Procedure: Tuberculin skin testOspedale L. Sacco – Polo UniversitarioNULLRecruiting18 Years80 YearsBoth100N/AItaly
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
6EUCTR2007-001190-28-GB
(EUCTR)
09/05/200717/04/2007Randomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis - TACITRandomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis - TACIT Rheumatoid Arthritis
MedDRA version: 9.1;Level: LLT;Classification code 10039073;Term: Rheumatoid arthritis
Product Name: Methotrexate
Product Code: Methotrexate
INN or Proposed INN: METHOTREXATE
Product Name: Sulfasalazine
Product Code: Sulfasalazine
INN or Proposed INN: SULFASALAZINE
Product Name: Hydroxychloroquine
Product Code: Hydroxychloroquine
INN or Proposed INN: Hydroxychloroquine
Product Name: Ciclosporin
Product Code: Ciclosporin
INN or Proposed INN: Ciclosporin
Product Name: Leflunomide
Product Code: Leflunomide
INN or Proposed INN: Leflunomide
Product Name: Sodium aurothiomalate (intramuscular gold)
Product Code: Sodium aurothiomalate (intramuscular gold)
INN or Proposed INN: Sodium aurothiomalate
Product Name: methylprednisolone
Product Code: methylprednisolone
INN or Proposed INN: Methylprednisolone
Product Name: Prednisolone
Product Code: Predniso
King's College LondonNULLNot RecruitingFemale: yes
Male: yes
190Phase 4United Kingdom

49. 全身性エリテマトーデス [臨床試験数:827,薬物数:638(DrugBank:168),標的遺伝子数:108,標的パスウェイ数:191
Searched query = "Systemic lupus erythematosus", "SLE"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 827 trial found
No.TrialIDDate_
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PhaseCountries
1ChiCTR2000038519
2020-10-012020-09-23A study of T lymphocyte subsets in children with systemic lupus erythematosusA study of T lymphocyte subsets in children with systemic lupus erythematosus systemic lupus erythematosus in childrenGold Standard:anti-nuclear antibodies;Index test:WBC, CD4+T cells, CD4+CCR7+CD95+T cells, CD4+CD45RA-CCR7+T cells, CD4+CD45RA-CCR7-Tcells;Tianjin Children's HospitalNULLPending817BothTarget condition:100;Difficult condition:50N/AChina

50. 皮膚筋炎/多発性筋炎 [臨床試験数:157,薬物数:207(DrugBank:76),標的遺伝子数:47,標的パスウェイ数:142
Searched query = "Dermatomyositis", "Polymyositis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 157 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000031286
2020-03-272020-03-26Establishment and validation of the risk prediction model of dermatomyositis combined with malignant tumor nomogramEstablishment and validation of the risk prediction model of dermatomyositis combined with malignant tumor nomogram DermatomyositicGold Standard:Clinical outcomes (whether combined with malignant tumor);Index test:The risk prediction model of dermatomyositis combined with malignant tumor nomogram;Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNULLRecruiting851BothTarget condition:240;Difficult condition:0China
2ChiCTR-DDD-16009687
2016-10-282016-10-28The precision diagnosis of dermatomyositis with malignant tumor or fatal interstitial lung diseaseThe precision diagnosis of dermatomyositis with malignant tumor or fatal interstitial lung disease DermatomyositisGold Standard:;Index test:;Department of Dermatology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong UniversityNULLRecruiting18BothTarget condition:0;Difficult condition:0China

53. シェーグレン症候群 [臨床試験数:234,薬物数:270(DrugBank:85),標的遺伝子数:49,標的パスウェイ数:174
Searched query = "Sjogren syndrome", "Sjögren syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 234 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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1ChiCTR2000035194
2020-10-012020-08-02The value of exosome miR29 for biomarker of primary Sjogren's syndrome with interstitial lung diseaseThe value of exosome miR29 for biomarker of primary Sjogren's syndrome with interstitial lung disease Sjogren's syndrome; Interstitial lung diseaseGold Standard:According to the clinical manifestations, chest imaging (cell-like change, ground glass change, solid shadow, mesh shadow), lung ventilation and diffusion function (FVC, DLCO), pathological biopsy and the elimination of ILD caused by other known reasons. If necessary, a surgical lung biopsy is feasible.;Index test:miRNA-29;Tongji Hosipital, Tongji University School of MedicineNULLRecruiting18BothTarget condition:60;Difficult condition:60China

65. 原発性免疫不全症候群 [臨床試験数:413,薬物数:581(DrugBank:97),標的遺伝子数:68,標的パスウェイ数:202
Searched query = "Primary immunodeficiency", "X-SCID", "Reticular dysgenesis", "Adenosine deaminase deficiency", "Omenn syndrome", "Purine nucleoside phosphorylase deficiency", "CD8 deficiency", "ZAP-70 deficiency", "MHC class I deficiency", "MHC class II deficiency", "Combined immunodeficiency", "Wiskott-Aldrich syndrome", "Telangiectasia ataxia", "Nijmegen breakage syndrome", "Bloom syndrome", "Immunodeficiency, centromere region instability, facial anomalies syndrome", "ICF syndrome", "PMS2 deficiency", "Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome", "RIDDLE syndrome", "Schimke syndrome", "Netherton syndrome", "Thymic hypoplasia", "DiGeorge syndrome", "22q11.2 deletion syndrome", "Hyper-IgE syndrome", "Hepatic venoocclusive immunodeficiency", "Immunodeficiency with central hepatic vein atresia", "Dyskeratosis congenita", "X-linked agammaglobulinaemia", "Common variable immunodeficiency", "Hyper-IgM syndrome", "Isolated IgG subclass deficiency", "Selective IgA deficiency", "Specific antibody production deficiency", "Infant transient hypogammaglobulinemia", "Chédiak-Higashi syndrome", "Chediak-Higashi syndrome", "X-linked lymphoproliferative syndrome", "SAP deficiency", "SH2D1A/SLAM-associated protein deficiency", "XIAP deficiency", "X-linked inhibitor of apoptosis deficiency", "Autoimmune lymphoproliferative syndrome", "ALPS", "Familial hemophagocytic syndrome", "Perforin deficiency", "Munc13-4 deficiency", "Syntaxin 11 deficiency", "Munc18-2 deficiency", "Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy", "APECED", "Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome", "IPEX syndrome", "CD25 deficiency", "ITCH deficiency", "Primary phagocytic dysfunction", "Severe congenital neutropenia", "Cyclic neutropenia", "Hermanskyi-Pudlak syndrome type 2", "Hermanskyi-Pudlak syndrome 2", "Griscelli syndrome type 2", "Griscelli syndrome 2", "p14 deficiency", "Warts, hypogammaglobulinemia, infections, myelokathexis syndrome", "WHIM syndrome", "Glycogen storage disease type Ib", "Leukocyte adhesion deficiency", "Shwachman-Diamond syndrome", "Chronic granulomatous disease", "Myeloperoxidase deficiency", "Mendelian susceptibility to mycobacterial disease", "MSMD", "Anhidrotic ectodermal dysplasia with immunodeficiency", "EDA-ID", "Interleukin-1 receptor-associated kinase-4 deficiency", "IRAK4 deficiency", "IMyD88 deficiency", "Chronic mucocutaneous candidiasis", "Epidermodysplasia verruciformis", "Herpes simplex encephalitis", "Caspase recruitment domain family member 9 deficiency", "CARD9 deficiency", "Trypanosomiasis", "Congenital complement deficiency", "C1q deficiency", "CC1r deficiency", "CC1s deficiency", "CC2 deficiency", "CC3 deficiency", "CC4 deficiency", "CC5 deficiency", "CC6 deficiency", "CC7 deficiency", "CC8 deficiency", "CC9 deficiency", "Factor D deficiency", "Properdin deficiency", "Factor I deficiency", "Factor H deficiency", "MASP1 deficiency", "3MC syndrome", "Mannose-binding protein-associated serine protease 2 deficiency", "MASP2 deficiency", "FCN3", "Hereditary angioedema type 1", "Hereditary angioedema type I", "C1 inhibitor deficiency type 1", "C1 inhibitor deficiency type I", "Hereditary angioedema type 2", "Hereditary angioedema type II", "C1 inhibitor deficiency type 2", "C1 inhibitor deficiency type II", "Hereditary angioedema type 3", "Hereditary angioedema type III", "C1 inhibitor deficiency type 3", "C1 inhibitor deficiency type III"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 413 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000032139
2020-09-012020-04-20Newborn screening and precision medical system construction for primary immunodeficiency diseaseNewborn screening and precision medical system construction for primary immunodeficiency disease primary immunodeficiencyGold Standard:1. Whether there is immune deficiency;
2. Primary or secondary, persistent or temporary;
3. The part and degree of the defect of immune system;
4. Molecular diagnosis: sequence the first / second generation genes to detect whether there is pathogenic gene mutation; detection of relative protein molecular.;Index test:PID newborn screening technology system based on TRECs/KRECs combined with quantitative PCR detection;
Children's Hospital of Chongqing Medical UniversityNULLRecruiting01BothTarget condition:50000;Difficult condition:0China

68. 黄色靱帯骨化症 [臨床試験数:2,薬物数:4(DrugBank:4),標的遺伝子数:1,標的パスウェイ数:3
Searched query = "Ossification of the ligamentum flavum", "Ossification of ligamentum flavum", "OLF"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000030380
2020-02-152020-02-29The diagnostic accuracy of CT-based ''Banner cloud sign'' for dural ossification in patients with thoracic ossification of the ligamentum flavum: a prospective, blinded, diagnostic accuracy study protocolThe diagnostic accuracy of CT-based ''Banner cloud sign'' for dural ossification in patients with thoracic ossification of the ligamentum flavum: a prospective, blinded, diagnostic accuracy study protocol ossification of ligamentum flavum combined with dural ossificationGold Standard:Operation notes.;Index test:CT images of thoracic spine: Banner clouds sign, Tram track sign and Comma sign.;Peking University Third HospitalNULLRecruiting099BothTarget condition:132;Difficult condition:0China

76. 下垂体性ゴナドトロピン分泌亢進症 [臨床試験数:25,薬物数:41(DrugBank:11),標的遺伝子数:3,標的パスウェイ数:10
Searched query = "Pituitary gonadotropin secretion hyperthyroidism", "Gonadotropin secreting pituitary adenoma", "Central precocious puberty", "Gonadotropin producing pituitary adenoma"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 25 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000034464
2020-09-012020-07-05First Morning Voided Urinary Gonadotropin Measurements for the Early Screening, Diagnosis and Follow-up of CPP PatientsFirst Morning Voided Urinary Gonadotropin Measurements for the Early Screening, Diagnosis and Follow-up of CPP Patients Central precocious pubertyGold Standard:Clinical outcome by CPP diagnostic standards;Index test:morning urine GN;Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and TechnologyNULLPending612BothTarget condition:400;Difficult condition:6000China
2ChiCTR2000038202
2020-09-012020-09-13AMH combined INHB for the diagnosis of female central precocious pubertyAMH combined INHB for the diagnosis of female central precocious puberty Central precocious pubertyGold Standard:GnRHa provoctive test;Index test:Anti Mullerian hormone, Inhibin B;Capital Institute of PediatricsNULLRecruiting58FemaleTarget condition:150;Difficult condition:150China

84. サルコイドーシス [臨床試験数:143,薬物数:221(DrugBank:79),標的遺伝子数:82,標的パスウェイ数:165
Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 143 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000036043
2020-10-012020-08-21A prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypical tuberculosis from sarcoidosisA prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypical tuberculosis from sarcoidosis sarcoidosis, tuberculosisGold Standard:Biopsy pathological specimen, and sputum AFB smear;Index test:XpertMTB/RIF Ultra;Shanghai Pulmonary Hospital Tongji University, School of MedicineNULLPending18BothTarget condition:72;Difficult condition:72China
2ChiCTR-DCD-15007110
2015-09-012015-09-20The clinical application of new methods for differential diagnosis of sarcoidosis andsputum negative tuberculosisThe clinical application of new methods for differential diagnosis of sarcoidosis andsputum negative tuberculosis sarcoidosis andsputum negative tuberculosisGold Standard:;Index test:;Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of MedicineNULLRecruiting18BothTarget condition:0;Difficult condition:0China

86. 肺動脈性肺高血圧症 [臨床試験数:1,083,薬物数:667(DrugBank:122),標的遺伝子数:98,標的パスウェイ数:185
Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 1,083 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
1ChiCTR2000036852
2020-10-012020-08-25Establishment of an artificial intelligence screening and evaluation system based on multimodal imaging of pulmonary arterial hypertension: Study on clinical diagnosis modelEstablishment of an artificial intelligence screening and evaluation system based on multimodal imaging of pulmonary arterial hypertension: Study on clinical diagnosis model pulmonary arterial hypertensionGold Standard:Right heart catheterization;Index test:multimodal imaging artificial intelligence screening and evaluation system;Shanghai Pulmonary HospitalNULLPendingBothTarget condition:1000;Difficult condition:1000NULL
2ChiCTR2000032622
2020-05-012020-05-04Research for right cardiac function evaluation and warning model of neonatal pulmonary arterial hypertensionResearch for right cardiac function evaluation and warning model of neonatal pulmonary arterial hypertension pulmonary arterial hypertensionGold Standard:Clinical outcome;Index test:echocardiographic;Sichuan Academy of Medical Sciences & Sichuan Provincial People's HospitalNULLPendingMaleTarget condition:100;Difficult condition:0China
3ChiCTR1900028152
2020-01-012019-12-13Serum interleukins-6: a predictive biomarker for connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH)Serum interleukins-6: a predictive biomarker for connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) pulmonary arterial hypertensionGold Standard:Clinical outcome;Index test:serum IL-6;Zhongda Hospital Affiliated to Southeast UniversityNULLPending1880BothTarget condition:200;Difficult condition:0N/AChina
4ChiCTR-DDD-16009406
2016-11-012016-10-14System Construction of Precious Diagnosis and Evaluation for Pulmonary Arterial HpyertensionSystem Construction of Precious Diagnosis and Evaluation for Pulmonary Arterial Hpyertension Pulmonary arterial hypertensionGold Standard:;Index test:;Shanghai Pulmonary HospitalNULLPendingBothTarget condition:0;Difficult condition:0China
5NCT01457170
(ClinicalTrials.gov)
January 201220/10/2011Effects of Apelin on the Lung Circulation in Pulmonary HypertensionInvestigating the Acute Pulmonary Vascular Haemodynamic Effects of Apelin in Pulmonary HypertensionPulmonary Arterial Hypertension;Heart FailureDrug: Apelin;Drug: Saline (Placebo)Golden Jubilee National HospitalNHS Lothian;Imperial College Healthcare NHS TrustRecruiting18 YearsN/ABoth63N/AUnited Kingdom

91. バッド・キアリ症候群 [臨床試験数:3,薬物数:4(DrugBank:3),標的遺伝子数:2,標的パスウェイ数:8
Searched query = "Budd-Chiari syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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PhaseCountries
1ChiCTR1800017925
2018-08-312018-08-22D-printed bidirectional angiography versus traditional angiography for the diagnosis and effect of Budd–Chiari Syndrome With Inferior Vena Cava Obstruction:-----A Prospective Single blind Randomized TrialD-printed bidirectional angiography versus traditional angiography for the diagnosis and effect of Budd–Chiari Syndrome With Inferior Vena Cava Obstruction:-----A Prospective Single blind Randomized Trial Budd-Chiari syndromeGold Standard:traditional angiography;Index test:3D-printed bidirectional angiography;Affiliated Hospital of Xuzhou Medical UniversityNULLPending1968BothTarget condition:60;Difficult condition:0NULL

93. 原発性胆汁性胆管炎 [臨床試験数:230,薬物数:215(DrugBank:51),標的遺伝子数:34,標的パスウェイ数:107
Searched query = "Primary biliary cholangitis", "Primary biliary cirrhosis", "PBC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 230 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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PhaseCountries
1ChiCTR2000032053
2020-05-012020-04-19Application value of ultrasonography combined with transient elastography for staging of hepatic fibrosis in patients with primary biliary cholangitis (PBC)Application value of ultrasonography combined with transient elastography for staging of hepatic fibrosis in patients with primary biliary cholangitis (PBC) primary biliary cholangitisGold Standard:Any two of the following items met:
1. increased biochemical indicators of cholestasis such as alkaline phosphatase;
2. positive serum AMA or AMA-M2;
3. hepatic histopathology.;Index test:high-frequency and low-frequency ultrasound?transient elastography (TE);
You'an Hospital, Capital Medical UniversityNULLPending1870BothTarget condition:100;Difficult condition:270N/AChina
2ChiCTR1900024836
2019-07-302019-07-30Exploration of non-invasive diagnostic model of liver fibrosis based on artificial intelligence in primary biliary cholangitis Clinical research protocolExploration of non-invasive diagnostic model of liver fibrosis based on artificial intelligence in primary biliary cholangitis Clinical research protocol Primary biliary cholangitisGold Standard:Liver biopsy pathology.;Index test:Non-invasive diagnostic model for liver fibrosis: including AST/PLT value index (APRI model), Forns model, S index, and based on this, a new non-invasive liver fibrosis diagnosis model is generated.;Beijing You'an Hospital, Capital Medical UniversityNULLRecruiting1880BothTarget condition:180;Difficult condition:180China

95. 自己免疫性肝炎 [臨床試験数:44,薬物数:57(DrugBank:26),標的遺伝子数:18,標的パスウェイ数:108
Searched query = "Autoimmune hepatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 44 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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1ChiCTR2000031051
2020-05-012020-03-21Study on the early diagnosis and prediction model of autoimmune hepatitis based on noninvasive clinical dataStudy on the early diagnosis and prediction model of autoimmune hepatitis based on noninvasive clinical data Autoimmune hepatitisGold Standard:liver biopsy;Index test:the early diagnosis and prediction model of autoimmune hepatitis based on noninvasive clinical data;The Sixth People's Hospital Affiliated To Shanghai Jiaotong UniversityNULLPendingMaleTarget condition:238;Difficult condition:0China

96. クローン病 [臨床試験数:2,209,薬物数:1,276(DrugBank:240),標的遺伝子数:166,標的パスウェイ数:210
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
4 / 2,209 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1ChiCTR2000037094
2020-09-012020-08-26Discovery and detection of a novel antigen for Crohn’s disease (CD)Discovery and detection of a novel antigen for Crohn’s disease (CD) Inflammatory Bowel DiseaseGold Standard:Chinese consensus on diagnosis and treatment in inflammatory bowel disease (2018, Beijing);Index test:anti-CABP, pANCA, ASCA;The First Affiliated Hospital of Anhui Medical UniversityNULLCompleted1880BothTarget condition:100;Difficult condition:100China
2ChiCTR2000029543
2020-02-082020-02-03A Model with serum biomarkers to Predict Infliximab Response in Patients with Crohn's DiseaseA Model with serum biomarkers to Predict Infliximab Response in Patients with Crohn's Disease Crohn's DiseaseGold Standard:Histology pathological examination; SES-CD endoscopy score;Index test:ELISA test for multiple serum cytokines;The First Hospital Affiliated to Sun Yat sen UniversityNULLRecruitingBothTarget condition:350;Difficult condition:0China
3ChiCTR1900022728
2019-05-012019-04-23Cohort study combined with omics screening for the early diagnostic markers in Crohn's diseaseCohort study combined with omics screening for the early diagnostic markers in Crohn's disease Crohn's diseaseGold Standard:Clinical outcome;Index test:Comprehensive serological markers, metabolomics, intestinal microbes, pathological features, imaging features of clinical subclinical CD, combined with clinical and endoscopic features, to explore early diagnosis of CD;The 7th Medical Center of the PLA General Hospital (Army general hospital)NULLPendingBothTarget condition:310;Difficult condition:160China
4ChiCTR-DDT-14004999
2013-07-012014-07-17Endoscopic Ultrasonography (EUS) Helps Differentiate Crohn's Disease from Intestinal TuberculosisEndoscopic Ultrasonography (EUS) Helps Differentiate Crohn's Disease from Intestinal Tuberculosis Crohn's disease and intestinal tuberculosisGold Standard:;Index test:;West China Hospital, Sichuan UniversityNULLCompleted1641BothTarget condition:0;Difficult condition:0China

97. 潰瘍性大腸炎 [臨床試験数:2,269,薬物数:1,331(DrugBank:241),標的遺伝子数:114,標的パスウェイ数:181
Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 2,269 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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sponsor
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PhaseCountries
1ChiCTR1800019676
2018-12-012018-11-22Diagnostic Value of probe-based Confocal Laser Endomicroscopy Score for assessment of numosal healing of ulcerative colitisDiagnostic Value of probe-based Confocal Laser Endomicroscopy Score for assessment of numosal healing of ulcerative colitis: a single center, prospective cohort study ulcerative colitisGold Standard:Histopathological examination;Index test:1, Gland density (grade)
2. Gland morphology (grade)
3. Vascular changes (grade);
Peking University First HospitalNULLPending1880BothTarget condition:40;Difficult condition:0China
2ChiCTR1900023689
2012-03-012019-06-07Comparison of white light endoscopy vs chromoendoscopy in the detection rate of dysplasia and colorectal cancer in ulcerative colitis: A Multicenter Long-term Follow-up Randomized Controlled Trial in ChinaComparison of white light endoscopy vs chromoendoscopy in the detection rate of dysplasia and colorectal cancer in ulcerative colitis: A Multicenter Long-term Follow-up Randomized Controlled Trial in China Ulcerative colitisGold Standard:Pathological examination;Index test:1. targeted biopsies were taken from all visible lesions when using white light endoscopy
2. using white light endoscopy, sequential 4-quadrantic random biopsies were taken at every 10-cm intervals colon from disease segments defined by the endoscopist in addition to targeted biopsies from all visible lesions;
3. tar;
Xijing Hospital of Digestive Diseases, Fourth Military Medical UniversityNULLCompleted1870BothTarget condition:141;Difficult condition:0N/AChina

98. 好酸球性消化管疾患 [臨床試験数:128,薬物数:147(DrugBank:40),標的遺伝子数:34,標的パスウェイ数:132
Searched query = "Eosinophilic gastrointestinal disease", "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "N-FPIES"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 128 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR-DOD-16009003
2016-08-042016-08-10Perspective Study On Eosinophilic GastroenteritisPerspective Study On Eosinophilic Gastroenteritis Eosinophilic GastroenteritisGold Standard:;Index test:;Endoscopy Center, Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-sen University.NULLRecruitingBothTarget condition:0;Difficult condition:0China

113. 筋ジストロフィー [臨床試験数:567,薬物数:442(DrugBank:93),標的遺伝子数:55,標的パスウェイ数:151
Searched query = "Muscular dystrophy", "Dystrophinopathies", "Myotilinopathy", "Laminopathy", "Caveolinopathy", "LGMD1C", "Desminopathy", "Sarcoglycanopathy", "α-dystroglycanopathy", "FCMD", "Walker-Warburg syndrome", "Muscle-eye-brain disease", "Myotonic dystrophy", "Integrin α7 deficient CMD", "Rigid spine syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 567 trial found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR1800018340
2018-09-122018-09-12Clinical study for cardiac MRI in evaluating early myocardial lesions in patients with muscular dystrophyClinical study for cardiac MRI in evaluating early myocardial lesions in patients with muscular dystrophy Muscular dystrophyGold Standard:Genomic sequencing, muscle biopsy;Index test:Myocardial strain, T1/T2mapping value, late delayed enhancement (LGE), myocardial first pass perfusion;Department of Radiology, West China Second Hospital, Sichuan UniversityNULLRecruiting418MaleTarget condition:200;Difficult condition:30China

158. 結節性硬化症 [臨床試験数:100,薬物数:62(DrugBank:16),標的遺伝子数:35,標的パスウェイ数:115
Searched query = "Tuberous sclerosis", "Tuberous sclerosis complex"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 100 trial found
No.TrialIDDate_
enrollment
Date_
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1ChiCTR-DDD-17010586
2016-01-012017-02-08Prenatal diagnosis of tuberous sclerosis by fetal echocardiography combined with high throughput gene sequencingPrenatal diagnosis of TSC using high-throughput gene sequencing combined with fetal echocardiography Tuberous sclerosis complexGold Standard:A Clinical diagnostic criteria of tuberous sclerosis (TSC) for the postnatal population
1. Definite diagnosis: 2 major features or 1 major feature and 2 minor teatures
2. Possible diagnosis: 1 major feature or 2 minor features
[major features: (1) Facial angiofibro or forehead plaque, (2) 'Nontraumatic' periungual&#;Index test:1. Prenatal diagnosis of TSC high-risk fetus by the traditional method (amniocentesis) using the gold standard;
2. Prenatal diagnosis of TSC high-risk fetus by maternal peripheral blood gene detection.;
An Zhen Hospital affiliated to Capital Medical University, Beijing;Beijing Key Laboratory of Fetal Heart Diseases and Maternal-Fetal MedicineNULLRecruitingFemaleTarget condition:30;Difficult condition:5China

162. 類天疱瘡(後天性表皮水疱症を含む。) [臨床試験数:70,薬物数:117(DrugBank:46),標的遺伝子数:30,標的パスウェイ数:128
Searched query = "Pemphigoid", "Epidermolysis bullosa acquisita"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 70 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR1800017560
2018-08-312018-08-04Association of serum D-dimer and PDF with the BP severityAssociation of serum D-dimer and PDF with the BP severity Bullous pemphigoidGold Standard:Clinical outcome;Index test:D-dimer, FDP, anti-BP180 IgG;the Second Affiliated Hospital, Xi'an Jiaotong UniversityNULLPending1890BothTarget condition:160;Difficult condition:0China

171. ウィルソン病 [臨床試験数:50,薬物数:59(DrugBank:17),標的遺伝子数:3,標的パスウェイ数:28
Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 50 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR1900023410
2019-06-012019-05-26The application of quantitative susceptibility mapping and blood and urine cell culture in Wilson's diseaseThe application of quantitative susceptibility mapping and blood and urine cell culture in Wilson's disease Wilson’s diseaseGold Standard:The main clinical diagnostic criteria: 1) liver disease history, liver disease symptoms or extravertebral system symptoms; 2) serum ceruloplasmin was significantly decreased and/or liver copper increased; 3) corneal Kayser-Fleischer ring; 4) positive family history.;Index test:Quantitative susceptibility mapping;Shanghai Tongren HospitalNULLRecruitingBothTarget condition:40;Difficult condition:20China
2ChiCTR-DDD-17010552
2017-01-252017-02-04Genetic diagnosis of Wilson's diseaseGenetic diagnosis of Wilson's disease Wilson DiseaseGold Standard:Clinical symptoms; Family history of genetic; Plasma ceruloplasmin levels;Urine copper levels of 24 hours; The nervous system of assessment and head imaging examination;Index test:Determination of gene sequence of the gene of ATP7B;Anhui Provincial HospitalNULLRecruitingBothTarget condition:20;Difficult condition:0China

218. アルポート症候群 [臨床試験数:16,薬物数:24(DrugBank:11),標的遺伝子数:5,標的パスウェイ数:27
Searched query = "Alport syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 16 trial found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000036550
2020-09-012020-08-24Enzyme-linked immunosorbent determination of urine IV collagen alpha chain early warning value for Alport syndromeEnzyme-linked immunosorbent determination of urine IV collagen alpha chain early warning value for Alport syndrome Alport syndromeGold Standard:Renal biopsy, skin biopsy and genetic test.;Index test:urine IV collagen a chain test;Children's Hospital of ShanghaiNULLRecruiting018BothTarget condition:60;Difficult condition:70China

222. 一次性ネフローゼ症候群 [臨床試験数:234,薬物数:241(DrugBank:78),標的遺伝子数:59,標的パスウェイ数:185
Searched query = "Primary nephrotic syndrome", "Minimal change nephrotic syndrome", "MCNS", "Membranous nephropathy", "Focal segmental glomerulosclerosis", "FSGS", "Membranoproliferative glomerulonephritis", "MPGN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 234 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR2000037467
2020-12-312020-08-28Effect of Tripterygium wilfordii polyglycoside tablets on the inhibition of TM on complement pathway and related inflammatory markers in membranous nephropathyThe complement pathway and related inflammatory factor markers in the treatment of idiopathic membranous nephropathy idiopathic membranous nephropathyGold Standard:Cell hemolysis test;Index test:Immunochemiluminescence (ECL) and flow cytometry (FCM) were used to determine the activity of each complement pathway and the target of complement;
Complement hemolysis test is usually used to determine the activity of total complement and single complement component, but it is difficult to be applied to clinical ;
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineNULLPending1880BothTarget condition:40;Difficult condition:40China
2NCT04387448
(ClinicalTrials.gov)
July 28, 202011/5/2020A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change DiseaseA Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change DiseaseKidney Diseases;Diabetic Nephropathies;Glomerulosclerosis, Focal Segmental;Nephrosis, Lipoid;Urologic Diseases;Diabetes Complications;Diabetes Mellitus;Endocrine System Diseases;Glomerulonephritis;Nephritis;NephrosisDrug: GFB-887;Drug: PlaceboGoldfinch Bio, Inc.NULLRecruiting18 Years75 YearsAll125Phase 2United States
3ChiCTR1900027128
2019-10-302019-11-01Validation of Anti-Phospholipase A2 Receptor Antibody ELISA in a Chinese Cohort With Idiopathic Membranous Nephropathy: a Multicenter Observational StudyThe Cut-off Value of Anti-Phospholipase A2 Receptor Antibody ELISA in Chinese Patients Membranous NephrologyGold Standard:Pathological diagnosis according to kidney biopsy(Chapter 7, 7.1 Evaluation of MN, KDIGO 2012);Index test:Serum PLA2R Antibody by ELISA;Department of Nephrology, The First Affiliated Hospital of Shandong First Medical UniversityNULLRecruitingBothTarget condition:288;Difficult condition:290N/AChina

224. 紫斑病性腎炎 [臨床試験数:10,薬物数:41(DrugBank:19),標的遺伝子数:15,標的パスウェイ数:56
Searched query = "Purpura nephritis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 10 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR1800017046
2018-07-152018-07-10The research of Gd - IgA1 with purpura nephritisThe research of Gd - IgA1 with purpura nephritis Henoch-Schnlein purpura nephritis;D69.005+Gold Standard:Allergic purpura diagnostic criteria: 1) the tangibility purpura; 2) the onset age < 20 years old; 3) with acute abdominal pain; 4) biopsy showed small veins and arteries around a neutrophil infiltration. In the above four standard, conform to article 2 or above can be diagnosed as allergic purpura.
Purpur;Index test:Gd-IgA1, IgA, IgG, C3;
College of Pediatrics, University of South China/Children's Hospital of Hu'nan ProvinceNULLRecruiting114BothTarget condition:250;Difficult condition:24China

227. オスラー病 [臨床試験数:49,薬物数:69(DrugBank:21),標的遺伝子数:23,標的パスウェイ数:132
Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 49 trial found
No.TrialIDDate_
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1ChiCTR1900027420
2018-01-012019-11-12genetic screening for hereditary hemorrhagic telangiectasiaInvestigation and applyling on the genetic screening kit for hereditary hemorrhagic telangiectasia hereditary hemorrhagic telangiectasiaGold Standard:Clinical outcomes;Index test:To identified the pathogenic variant through genetic testing for the coding region of ENG, ACVRL1, SMAD4 and BMP9.;Beijing Institute of OtolaryngologyNULLRecruitingBothTarget condition:54;Difficult condition:0China

230. 肺胞低換気症候群 [臨床試験数:8,薬物数:11(DrugBank:5),標的遺伝子数:18,標的パスウェイ数:27
Searched query = "Alveolar hypoventilation syndrome", "AHS", "Hypoventilation syndrome", "OHS", "CCHS", "Idiopathic central alveolar hypoventilation", "ICAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 8 trial found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR-DDT-11001215
2010-07-012011-03-05Double position CT investigation of OSAHSDouble position CT investigation of OSAHS Obstructive sleep apnea hypoventilation syndromeGold Standard:;Index test:;First Hospital of Peking universityNULLCompletedBothTarget condition:0;Difficult condition:0China

271. 強直性脊椎炎 [臨床試験数:531,薬物数:343(DrugBank:66),標的遺伝子数:41,標的パスウェイ数:141
Searched query = "Ankylosing spondylitis", "Spondylarthritis ankylopoietica"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 531 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1ChiCTR-DDD-17014196
2018-01-012017-12-28HLA-B27 tested by different methods and comparisonHLA-B27 tested by different methods and comparison Ankylosing spondylitisGold Standard:Detect HLA-B27 by cytometry;Index test:SSP and SSO;Dalian Blood CenterNULLRecruiting590BothTarget condition:200;Difficult condition:0China

291. ヒルシュスプルング病(全結腸型又は小腸型) [臨床試験数:13,薬物数:32(DrugBank:15),標的遺伝子数:0,標的パスウェイ数:0]
Searched query = "Hirschsprung disease, entire colon type", "Hirschsprung disease, small intestine type", "Hirschsprung disease", "Hirschprung disease", "Hirschsprung disease associated entercolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 13 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000035860
2020-10-012020-08-18Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung diseaseArtificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung disease Hirschsprung diseaseGold Standard:The speciemens and sections will be reveiwed by three senior pediatric gastroenterology pathologists under the novel pathological grading system of ganglion cells in Hirschsprung disease, and the results is regarded as the gold standard.;Index test:Artificial intelligence assisted whole-section patholgic diagnosis system;Xinhua Hospital, Shanghai Jiaotong University School of MedicineNULLPending016BothTarget condition:138;Difficult condition:138China

294. 先天性横隔膜ヘルニア [臨床試験数:12,薬物数:29(DrugBank:6),標的遺伝子数:5,標的パスウェイ数:14
Searched query = "Congenital diaphragmatic hernia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 12 trial found
No.TrialIDDate_
enrollment
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1NCT00257946
(ClinicalTrials.gov)
December 200522/11/2005Type of Material in Repair of Congenital Diaphragmatic HerniaProspective Randomized Trial Comparing Type of Material in Repair of Congenital Diaphragmatic HerniaCongenital Diaphragmatic HerniaProcedure: Repair of CDH w/SIS Gold;Procedure: Repair of CDH w/AllodermChildren's Mercy Hospital Kansas CityNULLTerminatedN/A2 MonthsBoth50Phase 3United States

296. 胆道閉鎖症 [臨床試験数:53,薬物数:56(DrugBank:31),標的遺伝子数:43,標的パスウェイ数:50
Searched query = "Biliary atresia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 53 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000032983
2020-08-012020-05-17Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic ModelDevelopment of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model Biliary atresiaGold Standard:Cholangiography combined with liver biopsy;Index test:MMP7;bile acid profile;Children's Hospital of Fudan UniversityNULLRecruitingBothTarget condition:600;Difficult condition:600China
2ChiCTR2000034127
2020-07-202020-06-25Application of MMP-7 in early diagnosis of neonatal biliary atresiaApplication of MMP-7 in early diagnosis of neonatal biliary atresia Biliary atresia diseaseGold Standard:Laparoscopic cholangiography;Index test:Serum MMP-7;Department of Pediatric Surgery, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyNULLPending0.1BothTarget condition:300;Difficult condition:0China
3ChiCTR1800019866
2019-01-012018-12-02Development and validation of novel diagnostic model for biliary atresiaDevelopment and validation of novel diagnostic model for biliary atresia: a multicenter diagnostic test biliary atresiaGold Standard:cholangiography combined with liver biopsy;Index test:Nomogram;Children's Hospital of Fudan UniversityNULLPendingBothTarget condition:1000;Difficult condition:200China
4ChiCTR1800017428
2018-08-152018-07-30Machine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemiaMachine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemia Biliary atresiaGold Standard:Surgical exploration, puncture biopsy, intraoperative cholangiography or percutaneous cholecystography;Index test:machine learning based on the gallbladder morphology;Department of Medical Ultrasonics, the First Affiliated Hospital of Sun Yat-sen UniversityNULLPendingBothTarget condition:500;Difficult condition:100China
5ChiCTR-DPD-15005847
2014-11-192015-01-19Evidence-based guideline of diagnosis and treatment of biliary atresiaEvidence-based guideline of diagnosis and treatment of biliary atresia biliary atresiaGold Standard:;Index test:;Children's Hospital of Fudan UniversityNULLPending018BothTarget condition:0;Difficult condition:0I (Phase 1 study)China

298. 遺伝性膵炎 [臨床試験数:93,薬物数:168(DrugBank:51),標的遺伝子数:48,標的パスウェイ数:134
Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 93 trial found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000037002
2020-10-012020-08-26Differential diagnosis of pancreatic cancer and chronic pancreatitis with serum miR-25A prospective study of serum miR-25 detection in differential diagnosis of pancreatic cancer and chronic pancreatitis pancreatic cancerGold Standard:Pancreatic cancer: pancreatic ductal adenocarcinoma originating from pancreatic ductal epithelium was confirmed by pathological examination (operative biopsy, puncture biopsy, cytological examination). Chronic pancreatitis: Clinically diagnosed as chronic pancreatitis, and no evidence to support the diagnosis of pancreatic cancer.;Index test:Serum miR-25;The First Affiliated Hospital of the Naval Medical University of the Chinese People's Liberation ArmyNULLPending1875BothTarget condition:150;Difficult condition:150China

299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 1,592 trial found
No.TrialIDDate_
enrollment
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1NCT02717650
(ClinicalTrials.gov)
August 25, 201610/3/2016The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis.Development; Feasibility/Safety and Validation of the Alfred Step Test Exercise Protocol (A-STEP) Developed for Adults With Cystic Fibrosis:Cystic Fibrosis;Fibrosis;Lung Diseases;Respiratory Diseases;Genetic Diseases;Pancreatic DiseasesOther: A-STEP;Other: A-STEP (New Protocol);Other: Comparator: CPET cycle ergometer (Gold Standard)The AlfredMonash UniversitySuspended18 YearsN/AAll30N/AAustralia

310. 先天異常症候群 [臨床試験数:10,薬物数:18(DrugBank:10),標的遺伝子数:3,標的パスウェイ数:7
Searched query = "Congenital anomalies syndrome", "Trisomy 1q", "9q34 deletion syndrome", "Cornelia de Lange syndrome", "CdLS", "Smith-Lemli-Opitz syndrome", "SLO syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 10 trial found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000035477
2020-08-112020-08-12Clinical study on the diagnosis of Smith Lemli Opitz syndrome by GC-MSClinical study on the diagnosis of Smith Lemli Opitz syndrome by GC-MS Smith-Lemli-Opitz syndromeGold Standard:Quantitative detection of 7-DHC;Index test:Detection of chol and 7-DHC in clinical samples by GC-MS;Obstetrics and Gynecology Hospital Affiliated to Fudan UniversityNULLPending01BothTarget condition:110;Difficult condition:0China

318. シトリン欠損症  [臨床試験数:2,薬物数:2(DrugBank:2),標的遺伝子数:0,標的パスウェイ数:0]
Searched query = "Citrin deficiency", "NICCD", "Adult-onset type II citrullinemia", "CTLN2"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
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1ChiCTR2000038114
2020-09-152020-09-11Molecular Diagnostic Study and Clinical Management of citrin deficiencyMolecular Diagnostic Study and Clinical Management of citrin deficiency Citrin deficiencyGold Standard:Sanger sequncing;Index test:Next-Generation Sequncing;Beijing Friendship Hospital Affiliated to Capital Medical UniversityNULLRecruitingBothTarget condition:60;Difficult condition:0N/AChina