:Oxygen    (DrugBank: Oxygen)

18 diseases
告示番号疾患名(ページ内リンク)臨床試験数
6パーキンソン病2
13多発性硬化症/視神経脊髄炎1
19ライソゾーム病1
46悪性関節リウマチ1
49全身性エリテマトーデス1
70広範脊柱管狭窄症2
84サルコイドーシス1
85特発性間質性肺炎12
86肺動脈性肺高血圧症6
88慢性血栓塞栓性肺高血圧症6
90網膜色素変性症2
96クローン病2
97潰瘍性大腸炎2
193プラダー・ウィリ症候群1
226間質性膀胱炎(ハンナ型)3
294先天性横隔膜ヘルニア1
299嚢胞性線維症8
330先天性気管狭窄症/先天性声門下狭窄症1

6. パーキンソン病 [臨床試験数:2,123,薬物数:2,046(DrugBank:324),標的遺伝子数:183,標的パスウェイ数:198
Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 2,123 trials found
No.TrialIDDate_
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1NCT03229174August 23, 201821/4/2017Brain Perfusion & Oxygenation in Parkinson's Disease With NOHEvaluation of Brain Perfusion and Oxygenation in PD Patients With Neurogenic Orthostatic Hypotension: 4 Week Comparison of Droxidopa Versus PlaceboParkinson Disease;Neurogenic Orthostatic HypotensionDrug: Droxidopa;Drug: PlaceboWilliam Ondo, MDLundbeck LLCRecruiting18 Years85 YearsAll28Phase 4United States
2NCT03407378June 26, 201815/1/2018A Study to Investigate a New Treatment in Patients With Parkinson's DiseaseA Proof of Concept Study to Investigate the Effect of IPT803 Adjunct Treatment in Patients With Parkinson's DiseaseParkinson DiseaseDrug: IPT803;Genetic: Optional pharmacogenetic assessment;Other: Questionnaires;Other: Optional Blood-Oxygen-level Dependent functionalMRI;Other: Motor Assessments before taking regular PD treatment;Other: Motor Assessments on regular PD treatmentTools4PatientNULLCompleted35 YearsN/AAll110Phase 1/Phase 2United States;Belgium;France

13. 多発性硬化症/視神経脊髄炎 [臨床試験数:3,050,薬物数:2,147(DrugBank:348),標的遺伝子数:244,標的パスウェイ数:228
Searched query = "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3,050 trial found
No.TrialIDDate_
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1NCT03983720January 21, 20207/6/2019Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?Sclerosis, MultipleOther: Evaluation of degree chronic fatigue.;Other: Questionnaires;Biological: Blood sample;Other: Cardiopulmonary evaluation;Device: Capacity of muscular oxygen extraction;Device: Sleep assessment;Device: Metabolic fatigue;Other: Neuromuscular evaluationCentre Hospitalier Universitaire de Saint EtienneNULLRecruiting18 Years70 YearsAll60Phase 2France

19. ライソゾーム病 [臨床試験数:784,薬物数:673(DrugBank:101),標的遺伝子数:68,標的パスウェイ数:184
Searched query = "Lysosomal storage disease", "Lysosomal disease", "Gaucher disease", "Niemann-Pick disease", "Niemann-Pick type C", "GM1-gangliosidosis", "GM1-gangliosidoses", "GM2-gangliosidosis", "GM2-gangliosidoses", "Tay-Sachs disease", "Sandhoff disease", "Krabbe disease", "Metachromatic leukodystrophy", "Multiple-sulfatase deficiency", "Farber disease", "Mucopolysaccharidosis type I", "Mucopolysaccharidosis I", "MPS I", "Hurler syndrome", "Scheie syndrome", "Mucopolysaccharidosis type II", "Mucopolysaccharidosis II", "MPS II", "Hunter syndrome", "Mucopolysaccharidosis type III", "Mucopolysaccharidosis III", "MPS III", "Sanfilippo syndrome", "Mucopolysaccharidosis type IV", "Mucopolysaccharidosis IV", "MPS IV", "MPS IVA", "Morquio syndrome", "Morquio A syndrome", "Mucopolysaccharidosis type VI", "Mucopolysaccharidosis VI", "MPS VI", "Maroteaux-Lamy syndrome", "Mucopolysaccharidosis type VII", "Mucopolysaccharidosis VII", "MPS VII", "Sly syndrome", "Mucopolysaccharidosis type IX", "Mucopolysaccharidosis IX", "MPS IX", "Hyaluronidase deficiency", "Sialidosis", "Galactosialidosis", "Mucolipidosis II", "Mucolipidosis type II", "I-cell disease", "Mucolipidosis III", "Mucolipidosis type III", "Alpha-Mannosidosis", "Alpha-Mannosidase Deficiency", "Beta-Mannosidosis", "Beta-Mannosidase Deficiency", "Fucosidosis", "Aspartylglucosaminuria", "Schindler disease", "Kanzaki disease", "Pompe disease", "Acid lipase deficiency", "Wolman disease", "Cholesterol ester storage disease", "Danon disease", "Free sialic acid storage disease", "Salla disease", "Ceroid lipofuscinosis", "Fabry disease", "Cystinosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 784 trial found
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1NCT02023086August 201410/12/2013Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry PatientsClinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Relation With Visual Field Loss in Fabry PatientsFabry DiseaseProcedure: Contrast sensitivity measurement;Procedure: Slit Lamp assessment and intra-ocular pressure measurement;Procedure: Visual field testing;Procedure: Oxygen flow at the optic nerve head measurement;Drug: Tropicamide;Device: OSOMEUniversité de MontréalGenzyme, a Sanofi CompanyCompleted18 YearsN/AAll8N/ACanada

46. 悪性関節リウマチ [臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 4,183 trial found
No.TrialIDDate_
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1NCT02984943January 19, 201715/11/2016The Effects of Hyperbaric Oxygen on Rheumatoid ArthritisThe Effects of Hyperbaric Oxygen on Rheumatoid Arthritis: A Pilot StudyRheumatoId ArthritisDevice: Hyperbaric OxygenDavid Grant U.S. Air Force Medical CenterNULLCompleted18 YearsN/AAll14N/AUnited States

49. 全身性エリテマトーデス [臨床試験数:827,薬物数:638(DrugBank:168),標的遺伝子数:108,標的パスウェイ数:191
Searched query = "Systemic lupus erythematosus", "SLE"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 827 trial found
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1ChiCTR-IOR-170128022017-09-262017-09-26Synergy effects and health regulation effect of oxygen-ozone therapy on systemic lupus erythematosus (SLE)Synergy effects and health regulation effect of oxygen-ozone therapy on systemic lupus erythematosus (SLE) systemic lupus erythematosus (SLE)the Controled Group:basic oral therapy;the Treated Group:basic oral therapy + Autologous blood transfusion with oxygen-ozone + acupoint injection with oxygen-ozone on ST 36;Guangdong Provincial Hospital of Chinese MedicineNULLRecruiting1865Boththe Controled Group:30;the Treated Group:30;China

70. 広範脊柱管狭窄症 [臨床試験数:91,薬物数:195(DrugBank:54),標的遺伝子数:60,標的パスウェイ数:85
Searched query = "Spinal stenosis", "Extensive spinal canal stenosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 91 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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1NCT03088306July 1, 201722/2/2017Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery PatientsComparative Effectiveness of Multi-modal Pain Management Versus Standard Intra- and Post-operative Analgesia: Randomized Controlled Clinical Trial to Reduce Post-operative Pain and Opioid Use Among Patients Undergoing Lumbar Spine SurgeryLumbar Spinal Stenosis;Lumbar Spinal Instability;Lumbar Spine DegenerationDrug: Standard analgesia use [Oxygen];Drug: Standard analgesia use [Hydromorphone];Drug: Standard analgesia use [Volatile Anesthesia];Drug: Standard analgesia use [Fentanyl];Drug: Multi-modal pain management [Acetaminophen + Gabapentin];Drug: Multi-modal pain management [Fentanyl];Drug: Multi-modal pain management [Intravenous Ketamine];Drug: Multi-modal pain management [Valium + Gabapentin]Johns Hopkins UniversityNorth American Spine SocietyCompleted18 Years100 YearsAll49Early Phase 1United States
2NCT02625194January 1, 201625/11/2015The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided IntubationThe Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided IntubationLumbar Spinal StenosisDrug: OxygenYonsei UniversityNULLCompleted20 Years60 YearsAll36N/AKorea, Republic of

84. サルコイドーシス [臨床試験数:143,薬物数:221(DrugBank:79),標的遺伝子数:82,標的パスウェイ数:165
Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 143 trial found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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1NCT02246023January 201515/9/2014Fractionated Versus Target-controlled Propofol Administration in BronchoscopyTarget-controlled Versus Manually-controlled Propofol Sedation in Flexible Bronchoscopy. A Randomized Non-inferiority Trial.Lung Cancer;Sarcoidosis;Interstitial PneumoniaDevice: Flexible bronchoscopy in moderate sedation;Device: Oxygen saturation;Device: Blood pressure;Device: Propofol dosage;Device: Recovery time after bronchoscopyDaniel FranzenB. Braun Melsungen AGCompleted18 Years85 YearsBoth78Phase 4Switzerland

85. 特発性間質性肺炎 [臨床試験数:514,薬物数:377(DrugBank:108),標的遺伝子数:97,標的パスウェイ数:204
Searched query = "Idiopathic interstitial pneumonia", "IIPs", "Idiopathic pulmonary fibrosis", "IPF", "Usual interstitial pneumonia", "UIP", "Non-specific interstitial pneumonia", "NSIP", "Acute interstitial pneumonia", "AIP", "Diffuse alveolar damage", "DAD", "COP", "Organizing pneumonia", "OP", "Desquamative interstitial pneumonia", "DIP", "Respiratory bronchiolitis - associated interstitial lung disease", "RB-ILD", "Lymphocytic interstitial pneumonia", "LIP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
12 / 514 trials found
No.TrialIDDate_
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1NCT04564664March 1, 201914/9/2020High-flow Oxygen Therapy During Exercise in Idiopathic Pulmonary FibrosisHigh-flow Oxygen Therapy During Exercise in Idiopathic Pulmonary Fibrosis: a Crossover Clinical TrialIdiopathic Pulmonary FibrosisDrug: OxygenParc de Salut MarHospitales Universitarios Virgen del RocíoRecruiting18 Years85 YearsAll10N/ASpain
2NCT03688334June 1, 201820/9/2018Acute Effects of Oxygen Supplementation Among IPF PatientsAcute Effects of Oxygen Supplementation During Exercise Among Patients With Idiopathic Pulmonary Fibrosis Without Resting HypoxemiaIdiopathic Pulmonary FibrosisDrug: Oxygen 40 %;Drug: Medical air (sham O2)George Papanicolaou HospitalNULLUnknown status18 Years80 YearsAll15N/AGreece
3EUCTR2017-001276-27-GB21/08/201703/05/2017A study to determine if GBT440 can increase the level of oxygen in the blood of people with Idiopathic Pulmonary Fibrosis (IPF) who need to use supplemental oxygen when resting.A Phase II open label study to evaluate the effect of GBT440 on hypoxemia in subjects with Idiopathic Pulmonary Fibrosis (IPF) who are using supplemental oxygen at rest (ZEPHYR) - ZEPHYR Idiopathic Pulmonary Fibrosis (IPF)
MedDRA version: 20.0 Level: PT Classification code 10021240 Term: Idiopathic pulmonary fibrosis System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders ;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Global Blood Therapeutics Inc.NULLNot Recruiting Female: yes
Male: yes
32 Human pharmacology (Phase 1): no Therapeut1c exploratory (Phase 2): yes Therapeut1c conf1rmatory - (Phase 3): no Therapeut1c use (Phase 4): noUnited States;United Kingdom
4NCT03050255November 201625/11/2016Short-term Effects of Supplemental Oxygen in Patients With IPFShort-term Effects of Supplemental Oxygen During Walking in Hypoxemic Patients With Idiopathic Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)Other: Medical air;Other: Oxygen (2Liter/min);Other: Oxygen (4Liter/min)Schön Klinik Berchtesgadener LandLinde AGCompletedN/AN/AAll53N/AGermany
5NCT02989168November 201628/11/2016Study to Evaluate the Effect of GBT440 Administered to Subjects With IPF on Supplemental Oxygen at RestA Phase II Open Label Study to Evaluate the Effect of GBT440 on Hypoxemia in Subjects With Idiopathic Pulmonary Fibrosis (IPF) Who Are Using Supplemental Oxygen at Rest (ZEPHYR)Idiopathic Pulmonary Fibrosis;HypoxemiaDrug: GBT440Global Blood TherapeuticsNULLTerminated45 Years85 YearsAll14Phase 2United States;United Kingdom
No.TrialIDDate_
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6NCT02551068December 20151/9/2015High Oxygen Delivery to Preserve Exercise Capacity in Idiopathic Pulmonary Fibrosis Patients Treated With NintedanibHigh Oxygen Delivery to Preserve Exercise Capacity in IPF Patients Treated With Nintedanib: The HOPE-IPF StudyIdiopathic Pulmonary FibrosisOther: 60% Oxygen;Other: Standard of CareUniversity of British ColumbiaBoehringer IngelheimRecruiting19 YearsN/AAll88N/ACanada
7NCT02267655May 20157/10/20143 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPFAn Exploratory, 3-Part, Clinical Study to Assess the Effect of Pulsed, Inhaled Nitric Oxide (iNO) on Functional Pulmonary Imaging Parameters in Subjects With World Health Organization (WHO) Group 3 Pulmonary Hypertension (PH) Associated With Chronic Obstructive Pulmonary Disease (COPD) on Long-Term Oxygen Therapy (LTOT) (Part 1) and in Subjects With WHO Group 3 PH Associated With Idiopathic Pulmonary Fibrosis (IPF) on LTOT (Part 2 and Part 3)Pulmonary Hypertension;Chronic Obstructive Pulmonary Disease;Idiopathic Pulmonary FibrosisDrug: inhaled Nitric Oxide - 30 mcg/kg IBW/hr;Drug: inhaled Nitric Oxide 5,10,15 mcg/Kg IBW/hr;Drug: inhaled nitric oxide 75 mcg/kg IBW/hrBellerophonNULLCompleted40 Years80 YearsAll8Phase 1Belgium
8EUCTR2014-003423-21-BE29/09/201429/08/2014Evaluation of impact of inhaled nitric oxide on pulmonary vessel blood volume measured by high resolution computed tomography (HRCT) in subjects with World Health Organization (WHO) Group 3 Pulmonary Hypertension (PH) Associated with Chronic Obstructive Pulmonary Disease (COPD) on Long-Term Oxygen Therapy (LTOT) (Part 1) and in subjects with WHO Group 3 Pulmonary Hypertension (PH) Associated with Idiopathic pulmonary fibrosis (IPF) on Long-Term Oxygen Therapy (LTOT) (Part 2).An Exploratory, Two-Part, Clinical Study to Assess the Effect of Pulsed, Inhaled Nitric Oxide (iNO) on Functional Pulmonary Imaging Parameters in Subjects with World Health Organization (WHO) Group 3 Pulmonary Hypertension (PH) Associated with Chronic Obstructive Pulmonary Disease (COPD) on Long-Term Oxygen Therapy (LTOT) (Part 1) and in Subjects with WHO Group 3 PH associated with Idiopathic pulmonary fibrosis (IPF) on LTOT (Part 2). Part 1: Pulmonary Hypertension (PH) Associated with Chronic Obstructive Pulmonary Disease (COPD) Part 2: Pulmonary Hypertension (PH) Associated with Idiopathic pulmonary fibrosis (IPF)
MedDRA version: 18.1Level: PTClassification code 10021240Term: Idiopathic pulmonary fibrosisSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders
MedDRA version: 18.1Level: LLTClassification code 10010952Term: COPDSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders
MedDRA version: 18.1Level: PTClassification code 10009033Term: Chronic obstructive pulmonary diseaseSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders
MedDRA version: 18.1Level: PTClassification code 10037400Term: Pulmonary hypertensionSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders
MedDRA version: 18.1Level: HLTClassification code 10037401Term: Pulmonary hypertensionsSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Trade Name: INOmax 400ppm mol/mol inhalation gas
Product Name: INO
INN or Proposed INN: NITRIC OXIDE
Bellerophon Pulse Technologies LLCNULLNot RecruitingFemale: yes
Male: yes
Phase 1;Phase 2Belgium
9NCT02248064July 201412/9/2014Auto-titrating Oxygen in Chronic Respiratory FailureThe Assessment of Intelligent Oxygen Therapy (iO2t) in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF)Chronic Obstructive Pulmonary Disease;Idiopathic Pulmonary FibrosisDevice: Auto-titrating oxygen systemImperial College LondonNULLCompleted18 YearsN/ABoth26N/AUnited Kingdom
10NCT01214187July 201130/9/2010Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary FibrosisPhase II Study of Inhaled CO for the Treatment of Idiopathic Pulmonary FibrosisIdiopathic Pulmonary FibrosisDrug: inhaled carbon monoxide;Other: OxygenBrigham and Women's HospitalNational Heart, Lung, and Blood Institute (NHLBI);University of California, San Francisco;University of Chicago;University of Illinois at Chicago;University of Michigan;Columbia University;Tulane University;University of WashingtonCompleted18 Years85 YearsAll58Phase 2United States
No.TrialIDDate_
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11JPRN-UMIN0000050982011/02/0118/02/2011A randomized trial of ambulatory oxygen in patients with idiopathic pulmonary fibrosis and desaturation but without resting hypoxemia idiopathic pulmonary fibrosisambulatory oxygen
ambulatory air
Department of Respiratory Medicine and Allergology, Kinki University School of MedicineNULLComplete: follow-up complete20years-oldNot applicableMale and Female20Not selectedJapan
12JPRN-UMIN0000252562009/01/0113/12/2016Benefits of supplemental oxygen on exercise capacity and dyspnea in IPF patients idiopathic pulmonary fibrosisoxygen gas
air gas
Tosei General HospitalNULLComplete: follow-up completeNot applicable75years-oldMale and Female106Not appl1cableJapan

86. 肺動脈性肺高血圧症 [臨床試験数:1,083,薬物数:667(DrugBank:122),標的遺伝子数:98,標的パスウェイ数:185
Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 1,083 trials found
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1NCT04207593April 1, 201917/12/2019The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With HypoxemiaProspective, Randomized, Controlled Trial of the Effect of Long-term Oxygen Therapy on 6-minute Walking Distance, Clinical Parameters and Hemodynamics in Patients With PAH and CTEPHOxygen Deficiency;Pulmonary Arterial Hypertension;CTEPHDrug: OxygenHeidelberg UniversityNULLRecruiting18 YearsN/AAll40Phase 2Germany
2EUCTR2018-001387-39-DE15/03/201930/01/2019The effect of oxygen therapy in patients with pulmonary Hypertension.A prospective, randomized, controlled trial to assess the effect of long-term oxygen therapy on 6-minute walking distance, clinical parameters and hemodynamics in patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) - SOPHA pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH);Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]Thoraxklinik-Heidelberg gGmbHNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
20 Human pharmacology (Phase 1): no Therapeut1c exploratory (Phase 2): yes Therapeut1c conf1rmatory - (Phase 3): no Therapeut1c use (Phase 4): noGermany
3NCT03683082June 5, 201820/9/2018Oxygen Treatment and Pulmonary Arterial HypertensionAcute Effects of Oxygen Supplementation Among Pulmonary Arterial Hypertension PatientsPulmonary Arterial HypertensionDrug: Oxygen supplementation;Drug: Sham O2 (medical air)George Papanicolaou HospitalNULLUnknown status18 Years80 YearsAll10N/AGreece
4NCT02661802January 201220/1/2016Effects Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger SyndromeAcute Effects of 40% Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger SyndromeEisenmenger Complex;Hypertension, PulmonaryOther: Oxygen SupplementationFederal University of São PauloNULLCompleted18 Years60 YearsBoth30N/ANULL
5NCT00626028September 200420/2/2008Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator TestingComparison of Supplemental Oxygen and Nitric Oxide for Inhalation Plus Oxygen in the Evaluation of the Reactivity of the Pulmonary Vasculature During Acute Pulmonary Vasodilator TestingIdiopathic Pulmonary Arterial Hypertension;CardiomyopathyDrug: Nitric Oxide for inhalation;Drug: Oxygen;Drug: Nitric Oxide plus OxygenMallinckrodtNULLCompletedN/A18 YearsAll136Phase 3United States;France;Netherlands;Spain;United Kingdom
No.TrialIDDate_
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6NCT00317486September 200321/4/2006Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyA Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Tracleer (Bosentan) on Oxygen Saturation and Cardiac Hemodynamics in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyPulmonary Arterial Hypertension Related to Eisenmenger PhysiologyDrug: bosentanActelionNULLCompleted12 YearsN/ABoth54Phase 4United States;Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom

88. 慢性血栓塞栓性肺高血圧症 [臨床試験数:145,薬物数:112(DrugBank:22),標的遺伝子数:13,標的パスウェイ数:52
Searched query = "Chronic thromboembolic pulmonary hypertension", "CTEPH", "Idiopathic chronic pulmonary thromboembolism"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 145 trials found
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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1NCT04207593April 1, 201917/12/2019The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With HypoxemiaProspective, Randomized, Controlled Trial of the Effect of Long-term Oxygen Therapy on 6-minute Walking Distance, Clinical Parameters and Hemodynamics in Patients With PAH and CTEPHOxygen Deficiency;Pulmonary Arterial Hypertension;CTEPHDrug: OxygenHeidelberg UniversityNULLRecruiting18 YearsN/AAll40Phase 2Germany
2EUCTR2018-001387-39-DE15/03/201930/01/2019The effect of oxygen therapy in patients with pulmonary Hypertension.A prospective, randomized, controlled trial to assess the effect of long-term oxygen therapy on 6-minute walking distance, clinical parameters and hemodynamics in patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) - SOPHA pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH);Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]Thoraxklinik-Heidelberg gGmbHNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
20 Human pharmacology (Phase 1): no Therapeut1c exploratory (Phase 2): yes Therapeut1c conf1rmatory - (Phase 3): no Therapeut1c use (Phase 4): noGermany
3NCT02558582September 201514/9/2015Effect of Exercise Training in Patients With Pulmonary HypertensionEffect of Exercise Training in Arterial and Chronic Thromboembolic Pulmonary Hypertension in Switzerland and Standardization With European CountriesHypertension, PulmonaryBehavioral: respiratory and exercise therapy;Behavioral: respiratory and exercise therapy with supplemental oxygenUniversity of ZurichNULLRecruiting18 YearsN/AAll32N/ASwitzerland
4JPRN-UMIN0000268822015/04/0110/04/2017Effect of oxygen administration on pulmonary vascular resistance and cardiac index in patients with chronic thromboembolic pulmonary hypertension.Effect of oxygen administration on pulmonary vascular resistance and cardiac index in patients with chronic thromboembolic pulmonary hypertension. - Effect of oxygen administration on PVR and CI in CTEPH. chronic thromboembolic pulmonary hypertension.Oxygen administrationDepartment of Cardiology, Hospital Organization Okayama Medical CenterNULLComplete: follow-up continuing20years-oldNot applicableMale and Female100Not appl1cableJapan
5NCT01884012May 201313/5/2013Effect of Long-term Oxygen Therapy on Exercise Capacity and Quality of Life in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary HypertensionPulmonary Arterial and Chronic Thromboembolic Pulmonary HypertensionProcedure: long term oxygen therapyUniversity of ZurichNULLCompleted16 Years85 YearsAll30Phase 3Switzerland
No.TrialIDDate_
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6NCT01748474December 20124/10/2012Effect of Short-term Oxygen During CPET in Pulmonary HypertensionEffect of Short-term Oxygen Therapy on Cardiopulmonary Exercise Capacity in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary HypertensionPulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension;Chronic Cardiorespiratory DiseaseProcedure: Supplemental oxygen via a maskUniversity of ZurichNULLCompleted20 Years80 YearsBoth20Phase 2Switzerland

90. 網膜色素変性症 [臨床試験数:103,薬物数:158(DrugBank:42),標的遺伝子数:52,標的パスウェイ数:107
Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 103 trials found
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1NCT02465749May 201522/5/2015Clinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis PigmentosaClinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis PigmentosaRetinitis PigmentosaDrug: Continuous oxygen;Device: blue light-absorbing sunglasses;Drug: Compound thrombosis capsule sig: 1.5g/tid;Drug: Ginkgo biloba pills sig: 300mg/tid;Drug: Vitamin B sig: 10mg/tid;Drug: Vitamin AD sig: 1 tablet/tidSun Yat-sen UniversityZhujiang Hospital;Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University;Guangzhou Jeeyor Medical Research Co.,Ltd.Not yet recruiting18 Years60 YearsBoth404Phase 0China
2NCT00461435January 200417/4/2007Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis PigmentosaSlowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis PigmentosaRetinitis PigmentosaProcedure: hyperbaric oxygen therapyAzienda Policlinico Umberto INULLCompleted20 Years70 YearsBothN/AItaly

96. クローン病 [臨床試験数:2,209,薬物数:1,276(DrugBank:240),標的遺伝子数:166,標的パスウェイ数:210
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 2,209 trials found
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1ChiCTR18000199582018-12-162018-12-09Combining infliximab with Hyperbaric Oxygen Therapy in Patients With Perianal Crohn's DiseaseCombining infliximab with Hyperbaric Oxygen Therapy in Patients With Perianal Crohn's Disease Crohn's diseaseCase series:Combining infliximab treatmentwith Hyperbaric Oxygen Therapy;Daping Hospital, Army Medical University (Third Military Medical University)NULLRecruiting1865BothCase series:60;China
2NCT01828190March 20138/4/2013The Influence of Hyperbaric Oxygen in Patients With Perianal Crohn's Disease Already Treated With TNF Alpha Blockers Treated With TNF Alpha BlockersProspective Open-label Study of the Efficacy of the Addition of Hyperbaric Oxygen to the Treatment of Patients With Perianal Fistulas Already Treated With TNF Alpha BlockersCrohn's Disease;Perianal FistulasOther: Hyperbaric oxygenAssaf-Harofeh Medical CenterNULLRecruiting18 Years70 YearsBoth50N/AIsrael

97. 潰瘍性大腸炎 [臨床試験数:2,269,薬物数:1,331(DrugBank:241),標的遺伝子数:114,標的パスウェイ数:181
Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 2,269 trials found
No.TrialIDDate_
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1NCT03494764September 7, 20174/4/2018Hyperbaric Oxygen Therapy for Ulcerative Colitis FlaresHyperbaric Oxygen Therapy for Moderate to Severe Ulcerative Colitis Flares: A Multi-Center Randomized TrialColitis, UlcerativeOther: Hyperbaric Oxygen TherapyDartmouth-Hitchcock Medical CenterFoundation for Clinical Research in IBD;The Eli and Edythe Broad Foundation;University of California, San Diego;Mayo Clinic;University of Pittsburgh Medical Center;Virginia Mason Memorial Hospital;University of Texas Southwestern Medical Center;University of Maryland, College Park;NYU Langone HealthActive, not recruiting18 YearsN/AAll30Phase 2United States
2NCT02144350August 201313/5/2014Hyperbaric Oxygen for Ulcerative ColitisHyperbaric Oxygen Therapy for Moderate to Severe Ulcerative Colitis Flares: A Multi-center Randomized Double Blind Sham Controlled TrialUlcerative ColitisProcedure: Hyperbaric oxygen;Procedure: Sham Hyperbaric AirDartmouth-Hitchcock Medical CenterMayo Clinic;University of PittsburghTerminated18 YearsN/AAll18Phase 2/Phase 3United States

193. プラダー・ウィリ症候群 [臨床試験数:95,薬物数:104(DrugBank:27),標的遺伝子数:50,標的パスウェイ数:63
Searched query = "Prader-Willi syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 95 trial found
No.TrialIDDate_
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1NCT03031626September 1, 201620/1/2017Oxygen Versus Medical Air for Treatment of CSA in Prader Will SyndromeComparison of Therapeutic Oxygen Versus Medical Air for the Treatment of Central Sleep Apnea in Infants and Children With Prader Willi Syndrome: A Proof of Concept StudySleep Apnea, Central;Prader-Willi SyndromeBiological: Medical Air vs OxygenThe Hospital for Sick ChildrenNULLRecruitingN/A2 YearsAll10Phase 4Canada

226. 間質性膀胱炎(ハンナ型) [臨床試験数:133,薬物数:151(DrugBank:46),標的遺伝子数:48,標的パスウェイ数:137
Searched query = "Interstitial cystitis with Hunners ulcer", "Interstitial cystitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 133 trials found
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1NCT03143920November 1, 20172/5/2017Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary BladderHyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder: A Feasibility TrialChronic Interstitial Cystitis;Painful Bladder Syndrome;Recurrent Urinary Tract InfectionCombination Product: Hyperbaric Oxygen Therapy-University of California, San DiegoNULLRecruiting35 Years70 YearsFemale40Early Phase 1United States
2NCT03693001June 1, 201628/9/2018HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia)Clinical and Morphological Effects of Hyperbaric Oxygen Therapy in Patients With Interstitial Cystitis Associated With FibromyalgiaFibromyalgia;Interstitial CystitisDevice: Intermittent Exposure to Oxygen via Oro-Nasal MaskUniversity of South FloridaUniversity of PadovaCompleted18 YearsN/AAll12N/ANULL
3NCT01069263February 201010/1/2010Comparative Study Between Hyperbaric Therapy and Intravesical Dimethyl Sulfoxide Instillation for Interstitial CystitisComparison Between Hyperbaric Oxygen Therapy (HBOT) and Intravesical Dimethyl Sulfoxide (DMSO) Instillation for the Treatment of Interstitial Cystitis - a Prospective, Randomized Cross-over TrialInterstitial CystitisOther: Hyperbaric Oxygen Therapy;Drug: DMSOAssaf-Harofeh Medical CenterNULLRecruiting18 Years85 YearsBoth60N/AIsrael

294. 先天性横隔膜ヘルニア [臨床試験数:12,薬物数:29(DrugBank:6),標的遺伝子数:5,標的パスウェイ数:14
Searched query = "Congenital diaphragmatic hernia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 12 trial found
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1NCT03787160March 22, 201810/7/2018Microbiome and Volatile Organic Compounds in Patients With CDHDetermining the Effect of Probiotics on Microbiome and Volatile Organic Compounds in Patients After Surgical Repair of Congenital Diaphragmatic HerniaCongenital Diaphragmatic HerniaDiagnostic Test: initial VOC;Diagnostic Test: initial fecal microbiome;Diagnostic Test: initial pulmonary microbiome;Diagnostic Test: Maximum oxygen uptake;Diagnostic Test: Functional residual capacity;Dietary Supplement: Probiotic treatment;Diagnostic Test: VOC probiotic;Diagnostic Test: Fecal microbiome probiotic;Diagnostic Test: Pulmonary microbiome probioticMedical University of GrazUniversity of RostockCompleted6 Years16 YearsAll18N/AAustria

299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
8 / 1,592 trials found
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1NCT03965832May 24, 201924/5/2019HFNT During Exercise in CFA Pilot Study to Evaluate the Feasibility of Using High-flow Nasal Therapy During Exercise in Patients With Cystic Fibrosis and Severe Lung DiseaseCystic FibrosisDevice: HFNT during exercise;Device: Standard oxygen therapy/RAThe Leeds Teaching Hospitals NHS TrustNULLRecruiting18 YearsN/AAll20N/AUnited Kingdom
2NCT03902236March 1, 20191/4/2019Reaction Time and Postural Control in Individuals With Cystic Fibrosis and BronchiectasisEvaluation of Reaction Time and Postural Control in Individuals With Cystic Fibrosis and BronchiectasisCystic Fibrosis;BronchiectasisOther: Reaction Time and Postural Control;Other: Muscle oxygenation;Other: Exercise capacity;Other: BalanceHacettepe UniversityNULLRecruiting6 Years18 YearsAll60Turkey
3NCT02684552February 201612/2/2016Non Invasive Ventilation During Physical Training in Cystic FibrosisPhysiotherapist in Charge of the StudyCystic FibrosisDevice: Non invasive ventilation;Device: OxygenKarolinska University HospitalNULLCompleted18 Years90 YearsBoth8N/ASweden
4NCT02262871December 20147/10/2014HFN Versus NIV in Cystic Fibrosis. The HIFEN StudyRandomized Cross-over Physiologic Study of High Flow Nasal Oxygen Cannula Versus Non-invasive Ventilation in Cystic Fibrosis. The HIFEN StudyCystic FibrosisDevice: High flow nasal oxygen cannula;Device: Noninvasive ventilationSt. Michael's Hospital, TorontoNULLCompleted18 YearsN/AAll15N/ACanada
5NCT01586728October 201218/1/2012Oxygen Therapy in Cystic FibrosisIndication and Benefits of Nocturnal Oxygen Therapy in Cystic FibrosisCystic FibrosisOther: Air - oxygen;Other: Oxygen - AirAssistance Publique - Hôpitaux de ParisVaincre la MucoviscidoseTerminated6 YearsN/ABoth8N/AFrance
No.TrialIDDate_
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6NCT01731015January 201216/11/2012Imaging Lung Function Using Oxygen Enhanced MRIA Pilot Study for Evaluation of Regional Lung Function in Normal Subjects and Subjects With Airway and Lung Disorders Using 1H Magnetic Resonance Imaging With Oxygen as a Contrast AgentCOPD;Asthma;Cystic Fibrosis;Emphysema;Small Airways DiseaseDrug: Medical Grade OxygenHal C CharlesNULLCompleted18 Years90 YearsBoth15Phase 1United States
7NCT01710449September 200917/10/2012Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With OxygenEvaluation of Regional Ventilation in Normal Subjects and Subjects With Airway and Lung Disorders (COPD, Asthma, Emphysema, Small Airway Disease and Cystic Fibrosis) Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen.COPD;Asthma;Cystic Fibrosis;Emphysema;Small Airways DiseasesDrug: perfluorinated gas/oxygen mixtureHal C CharlesNULLCompleted18 YearsN/ABoth44Phase 1United States
8NCT00157183March 20039/9/2005Non-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen DesaturationNon-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen DesaturationCystic FibrosisDevice: Nocturnal oxygen , nocturnal bi-level positive pressure ventilationBayside HealthNational Health and Medical Research Council, Australia;Monash University;Cystic Fibrosis AustraliaCompleted18 Years75 YearsBoth59Phase 1/Phase 2Australia

330. 先天性気管狭窄症/先天性声門下狭窄症 [臨床試験数:1,薬物数:3(DrugBank:2),標的遺伝子数:0,標的パスウェイ数:0]
Searched query = "Congenital tracheal stenosis", "Congenital subglottic stenosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 1 trial found
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1JPRN-JMA-IIA0035701/07/201819/06/2018Phase II trial of helium / oxygen mixed gas for respiratory failure secondary to airway obstructive lesion in childrenPhase II trial of helium / oxygen mixed gas for respiratory failure secondary to airway obstructive lesion in children Respiratory failure due to airway obstructive lesion such as acute bronchiolitis, congenital tracheal stenosis, bronchial asthma attackIntervention type:DRUG. Intervention1:Helium / oxygen mixed gas inhalation therapy, Dose form:INSUFFLATION, Route of administration:INHALATIONAL, intended dose regimen:Helium / oxygen mixed gas .Tokyo Metropolitan Children's Medical CenterNational Center for Child Health and DevelopmentRecruitingNo Limit<20 YEARSBOTH15Phase 2Japan