DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

A B C D E F G H I J K L M N O PQR S T U V WXYZother

210 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: KIT 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
2	Acute myeloid leukemia 💬	1件: KIT 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
3	Acute myeloid leukemia 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
4	Acute myeloid leukemia 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5	Acute myeloid leukemia 💬	1件: KIT 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
6	Acute myeloid leukemia 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
7	Acute myeloid leukemia 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
8	Adherens junction 💬	1件: EGFR 💬	D03455 💬	Cetuximab	5件: 34, 51, 86, 89, 331 💬
9	Adherens junction 💬	1件: FGFR1 💬	D10481 💬	Nintedanib	5件: 51, 85, 89, 227, 228 💬
10	Adherens junction 💬	3件: FYN, SRC, YES1 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
11	Adherens junction 💬	3件: FYN, SRC, YES1 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
12	Adherens junction 💬	1件: IGF1R 💬	D09680 💬	Teprotumumab	1件: 51 💬
13	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
14	Adipocytokine signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
15	Adipocytokine signaling pathway 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
16	Adipocytokine signaling pathway 💬	1件: TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
17	Adipocytokine signaling pathway 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
18	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
19	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
20	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
21	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
22	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
23	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
24	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
25	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D01450 💬	Bupivacaine	8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
26	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D07552 💬	Bupivacaine	8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
27	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D00358 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
28	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D02086 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
29	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D08127 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
30	African trypanosomiasis 💬	4件: IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
31	African trypanosomiasis 💬	1件: IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
32	African trypanosomiasis 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
33	African trypanosomiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
34	AGE-RAGE signaling pathway in diabetic complications 💬	5件: CCL2, IL1A, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
35	AGE-RAGE signaling pathway in diabetic complications 💬	1件: IL1A 💬	D11253 💬	Bermekimab	1件: 51 💬
36	AGE-RAGE signaling pathway in diabetic complications 💬	2件: IL1A, IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
37	AGE-RAGE signaling pathway in diabetic complications 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
38	AGE-RAGE signaling pathway in diabetic complications 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
39	AGE-RAGE signaling pathway in diabetic complications 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
40	AGE-RAGE signaling pathway in diabetic complications 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
41	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
42	Alcoholism 💬	1件: DRD2 💬	D00702 💬	Buspirone	2件: 6 , 51 💬
43	Alcoholism 💬	1件: DRD2 💬	D07593 💬	Buspirone	2件: 6 , 51 💬
44	Alcoholism 💬	1件: DRD2 💬	D01745 💬	Domperidone	5件: 6 , 13, 17, 51, 230 💬
45	Alcoholism 💬	1件: DRD2 💬	D07868 💬	Domperidone	5件: 6 , 13, 17, 51, 230 💬
46	Alcoholism 💬	1件: DRD2 💬	D00726 💬	Metoclopramide	1件: 51 💬
47	Alcoholism 💬	1件: DRD2 💬	D02213 💬	Metoclopramide	1件: 51 💬
48	Alcoholism 💬	1件: DRD2 💬	D05008 💬	Metoclopramide	1件: 51 💬
49	Alcoholism 💬	1件: DRD2 💬	D01348 💬	Terguride	2件: 51, 86 💬
50	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
51	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
52	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
53	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
54	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
55	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
56	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
57	Allograft rejection 💬	2件: IL10, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
58	Allograft rejection 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
59	Allograft rejection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
60	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
61	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
62	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
63	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
64	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
65	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
66	Alzheimer disease 💬	1件: IL1A 💬	D11253 💬	Bermekimab	1件: 51 💬
67	Alzheimer disease 💬	2件: IL1A, IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
68	Alzheimer disease 💬	4件: IL1A, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
69	Alzheimer disease 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
70	Alzheimer disease 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
71	Alzheimer disease 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
72	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
73	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
74	Alzheimer disease 💬	1件: PSMB5 💬	D03150 💬	Bortezomib	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
75	Alzheimer disease 💬	1件: PTGS2 💬	D00217 💬	Acetaminophen	16件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
76	Alzheimer disease 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
77	Alzheimer disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
78	Alzheimer disease 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D09587 💬	Brentuximab vedotin	2件: 49, 51 💬
79	Amoebiasis 💬	4件: IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
80	Amoebiasis 💬	1件: IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
81	Amoebiasis 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
82	Amoebiasis 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
83	Amoebiasis 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
84	Amoebiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
85	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
86	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
87	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
88	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
89	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
90	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
91	Amphetamine addiction 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
92	Amphetamine addiction 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
93	AMPK signaling pathway 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
94	AMPK signaling pathway 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
95	AMPK signaling pathway 💬	1件: HMGCR 💬	D01915 💬	Rosuvastatin	11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
96	AMPK signaling pathway 💬	1件: HMGCR 💬	D08492 💬	Rosuvastatin	11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
97	AMPK signaling pathway 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
98	AMPK signaling pathway 💬	1件: IGF1R 💬	D09680 💬	Teprotumumab	1件: 51 💬
99	AMPK signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
100	Amyotrophic lateral sclerosis 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
101	Amyotrophic lateral sclerosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
102	Amyotrophic lateral sclerosis 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
103	Amyotrophic lateral sclerosis 💬	1件: PSMB5 💬	D03150 💬	Bortezomib	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
104	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
105	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
106	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
107	Amyotrophic lateral sclerosis 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D09587 💬	Brentuximab vedotin	2件: 49, 51 💬
108	Antifolate resistance 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
109	Antifolate resistance 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
110	Antifolate resistance 💬	1件: IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
111	Antifolate resistance 💬	3件: IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
112	Antifolate resistance 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
113	Antifolate resistance 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
114	Antifolate resistance 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
115	Antigen processing and presentation 💬	1件: TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
116	Antigen processing and presentation 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
117	Antigen processing and presentation 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
118	Apelin signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
119	Apelin signaling pathway 💬	1件: PDE3B 💬	D01896 💬	Cilostazol	2件: 51, 70 💬
120	Apoptosis 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
121	Apoptosis 💬	1件: TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
122	Apoptosis 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
123	Apoptosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
124	Arachidonic acid metabolism 💬	2件: PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	16件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
125	Arachidonic acid metabolism 💬	2件: PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
126	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
127	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
128	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
129	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
130	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
131	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
132	Asthma 💬	2件: IL10, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
133	Asthma 💬	1件: TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
134	Asthma 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
135	Autoimmune thyroid disease 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
136	Autoimmune thyroid disease 💬	1件: IL10 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
137	Autophagy - animal 💬	1件: IGF1R 💬	D09680 💬	Teprotumumab	1件: 51 💬
138	Autophagy - animal 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
139	Autophagy - other 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
140	Axon guidance 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
141	Axon guidance 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
142	Axon guidance 💬	1件: ABL1 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
143	Axon guidance 💬	4件: ABL1, EPHA2, FYN, SRC 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
144	Axon guidance 💬	4件: ABL1, EPHA2, FYN, SRC 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
145	Axon guidance 💬	1件: CXCR4 💬	D08971 💬	Plerixafor	6件: 19, 20, 51, 65, 285, 299 💬
146	Axon guidance 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
147	Axon guidance 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
148	Axon guidance 💬	2件: ROCK1, ROCK2 💬	D07941 💬	Fasudil	2件: 2 , 51 💬
149	B cell receptor signaling pathway 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
150	B cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
151	B cell receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
152	Bacterial invasion of epithelial cells 💬	1件: SRC 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
153	Bacterial invasion of epithelial cells 💬	1件: SRC 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
154	Bile secretion 💬	1件: HMGCR 💬	D00887 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
155	Bile secretion 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
156	Bile secretion 💬	1件: HMGCR 💬	D01915 💬	Rosuvastatin	11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
157	Bile secretion 💬	1件: HMGCR 💬	D08492 💬	Rosuvastatin	11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
158	Bile secretion 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
159	Biosynthesis of cofactors 💬	2件: DHFR, DHFR2 💬	D00142 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
160	Biosynthesis of cofactors 💬	2件: DHFR, DHFR2 💬	D02115 💬	Methotrexate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
161	Bladder cancer 💬	1件: EGFR 💬	D03455 💬	Cetuximab	5件: 34, 51, 86, 89, 331 💬
162	Bladder cancer 💬	1件: FGFR3 💬	D10481 💬	Nintedanib	5件: 51, 85, 89, 227, 228 💬
163	Bladder cancer 💬	1件: SRC 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
164	Bladder cancer 💬	1件: SRC 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
165	Breast cancer 💬	1件: EGFR 💬	D03455 💬	Cetuximab	5件: 34, 51, 86, 89, 331 💬
166	Breast cancer 💬	2件: FGFR1, FLT4 💬	D10481 💬	Nintedanib	5件: 51, 85, 89, 227, 228 💬
167	Breast cancer 💬	1件: IGF1R 💬	D09680 💬	Teprotumumab	1件: 51 💬
168	Breast cancer 💬	1件: KIT 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
169	Breast cancer 💬	1件: KIT 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
170	Breast cancer 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
171	Breast cancer 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
172	Breast cancer 💬	1件: KIT 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
173	Breast cancer 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
174	Breast cancer 💬	1件: PGR 💬	D00951 💬	Medroxyprogesterone acetate	3件: 49, 51, 60 💬
175	Breast cancer 💬	1件: PGR 💬	D08166 💬	Medroxyprogesterone acetate	3件: 49, 51, 60 💬
176	C-type lectin receptor signaling pathway 💬	4件: IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
177	C-type lectin receptor signaling pathway 💬	1件: IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
178	C-type lectin receptor signaling pathway 💬	2件: IL6, TNF 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
179	C-type lectin receptor signaling pathway 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
180	C-type lectin receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
181	C-type lectin receptor signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
182	C-type lectin receptor signaling pathway 💬	1件: PTGS2 💬	D00217 💬	Acetaminophen	16件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
183	C-type lectin receptor signaling pathway 💬	1件: PTGS2 💬	D00109 💬	Acetylsalicylic acid	14件: 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
184	C-type lectin receptor signaling pathway 💬	1件: SRC 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
185	C-type lectin receptor signaling pathway 💬	1件: SRC 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
186	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
187	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
188	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
189	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
190	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
191	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
192	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
193	Calcium signaling pathway 💬	1件: CXCR4 💬	D08971 💬	Plerixafor	6件: 19, 20, 51, 65, 285, 299 💬
194	Calcium signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
195	Calcium signaling pathway 💬	1件: EDNRA 💬	D07741 💬	Zibotentan	1件: 51 💬
196	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D01227 💬	Bosentan	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
197	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D07538 💬	Bosentan	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
198	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D10135 💬	Macitentan	5件: 51, 85, 86, 88, 210 💬
199	Calcium signaling pathway 💬	1件: EGFR 💬	D03455 💬	Cetuximab	5件: 34, 51, 86, 89, 331 💬
200	Calcium signaling pathway 💬	8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬	D10481 💬	Nintedanib	5件: 51, 85, 89, 227, 228 💬
201	Calcium signaling pathway 💬	1件: HRH1 💬	D00300 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
202	Calcium signaling pathway 💬	1件: HRH1 💬	D00669 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
203	Calcium signaling pathway 💬	1件: HRH1 💬	D02419 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
204	Calcium signaling pathway 💬	1件: HRH1 💬	D03285 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
205	Calcium signaling pathway 💬	1件: HRH1 💬	D03360 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
206	Calcium signaling pathway 💬	1件: HRH1 💬	D03854 💬	Diphenhydramine	8件: 11, 49, 51, 70, 86, 96, 222, 256 💬
207	Calcium signaling pathway 💬	1件: HTR4 💬	D09205 💬	Prucalopride	3件: 13, 51, 96 💬
208	Calcium signaling pathway 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
209	Calcium signaling pathway 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
210	Calcium signaling pathway 💬	2件: PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
211	Calcium signaling pathway 💬	1件: PDGFRB 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
212	Calcium signaling pathway 💬	1件: PDGFRB 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
213	Calcium signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
214	Calcium signaling pathway 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
215	Calcium signaling pathway 💬	1件: PTGER1 💬	D00180 💬	Alprostadil	2件: 51, 70 💬
216	Calcium signaling pathway 💬	1件: PTGER1 💬	D02705 💬	Alprostadil	2件: 51, 70 💬
217	Calcium signaling pathway 💬	1件: TBXA2R 💬	D01896 💬	Cilostazol	2件: 51, 70 💬
218	Calcium signaling pathway 💬	1件: TBXA2R 💬	D04500 💬	Ifetroban	3件: 51, 86, 113 💬
219	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
220	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
221	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
222	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
223	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
224	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
225	cAMP signaling pathway 💬	1件: DRD2 💬	D01745 💬	Domperidone	5件: 6 , 13, 17, 51, 230 💬
226	cAMP signaling pathway 💬	1件: DRD2 💬	D07868 💬	Domperidone	5件: 6 , 13, 17, 51, 230 💬
227	cAMP signaling pathway 💬	1件: DRD2 💬	D00726 💬	Metoclopramide	1件: 51 💬
228	cAMP signaling pathway 💬	1件: DRD2 💬	D02213 💬	Metoclopramide	1件: 51 💬
229	cAMP signaling pathway 💬	1件: DRD2 💬	D05008 💬	Metoclopramide	1件: 51 💬
230	cAMP signaling pathway 💬	1件: DRD2 💬	D01348 💬	Terguride	2件: 51, 86 💬
231	cAMP signaling pathway 💬	2件: DRD2, HTR1A 💬	D00702 💬	Buspirone	2件: 6 , 51 💬
232	cAMP signaling pathway 💬	2件: DRD2, HTR1A 💬	D07593 💬	Buspirone	2件: 6 , 51 💬
233	cAMP signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
234	cAMP signaling pathway 💬	1件: EDNRA 💬	D01227 💬	Bosentan	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
235	cAMP signaling pathway 💬	1件: EDNRA 💬	D07538 💬	Bosentan	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
236	cAMP signaling pathway 💬	1件: EDNRA 💬	D10135 💬	Macitentan	5件: 51, 85, 86, 88, 210 💬
237	cAMP signaling pathway 💬	1件: EDNRA 💬	D07741 💬	Zibotentan	1件: 51 💬
238	cAMP signaling pathway 💬	1件: HTR4 💬	D09205 💬	Prucalopride	3件: 13, 51, 96 💬
239	cAMP signaling pathway 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
240	cAMP signaling pathway 💬	2件: PDE3A, PDE3B 💬	D01896 💬	Cilostazol	2件: 51, 70 💬
241	cAMP signaling pathway 💬	1件: PDE4A 💬	D00302 💬	Dipyridamole	5件: 46, 49, 51, 66, 224 💬
242	cAMP signaling pathway 💬	2件: ROCK1, ROCK2 💬	D07941 💬	Fasudil	2件: 2 , 51 💬
243	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
244	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
245	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
246	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
247	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
248	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
249	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
250	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
251	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
252	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
253	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
254	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
255	Cell adhesion molecules 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
256	Cell adhesion molecules 💬	1件: PDCD1 💬	D10316 💬	Nivolumab	12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
257	Cell cycle 💬	1件: ABL1 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
258	Cell cycle 💬	1件: ABL1 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
259	Cell cycle 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
260	Cell cycle 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
261	Cell cycle 💬	1件: ABL1 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
262	Cell cycle 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
263	Cellular senescence 💬	1件: CACNA1D 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
264	Cellular senescence 💬	1件: CACNA1D 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
265	Cellular senescence 💬	1件: CACNA1D 💬	D07450 💬	Amlodipine	4件: 13, 51, 67, 298 💬
266	Cellular senescence 💬	1件: CACNA1D 💬	D00616 💬	Diltiazem	3件: 51, 58, 86 💬
267	Cellular senescence 💬	1件: CACNA1D 💬	D03830 💬	Diltiazem	3件: 51, 58, 86 💬
268	Cellular senescence 💬	1件: CACNA1D 💬	D07845 💬	Diltiazem	3件: 51, 58, 86 💬
269	Cellular senescence 💬	1件: IL1A 💬	D11253 💬	Bermekimab	1件: 51 💬
270	Cellular senescence 💬	1件: IL1A 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬
271	Cellular senescence 💬	2件: IL1A, IL6 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
272	Cellular senescence 💬	1件: IL6 💬	D08976 💬	Pomalidomide	6件: 28, 34, 51, 85, 227, 331 💬
273	Cellular senescence 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
274	Cellular senescence 💬	1件: NFKB1 💬	D01146 💬	Iguratimod	4件: 46, 51, 53, 271 💬
275	Cellular senescence 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
276	Cellular senescence 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	32件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
277	Cellular senescence 💬	3件: TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	4件: 51, 85, 222, 274 💬
278	Central carbon metabolism in cancer 💬	1件: EGFR 💬	D03455 💬	Cetuximab	5件: 34, 51, 86, 89, 331 💬
279	Central carbon metabolism in cancer 💬	5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬	D10481 💬	Nintedanib	5件: 51, 85, 89, 227, 228 💬
280	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
281	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
282	Central carbon metabolism in cancer 💬	3件: KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	5件: 6 , 8 , 34, 51, 86 💬
283	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRB 💬	D03658 💬	Dasatinib	2件: 51, 85 💬
284	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRB 💬	D06414 💬	Dasatinib	2件: 51, 85 💬
285	Central carbon metabolism in cancer 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
286	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	4件: 13, 51, 67, 298 💬
287	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	4件: 13, 51, 67, 298 💬
288	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	4件: