DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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49 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
2	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
3	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
4	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
5	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
6	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
7	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
8	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
9	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
11	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
14	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
15	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
16	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
17	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
18	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
19	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
20	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
21	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
22	Apelin signaling pathway 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
23	Apelin signaling pathway 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
24	Apelin signaling pathway 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
25	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
26	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
27	Calcium signaling pathway 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
28	Calcium signaling pathway 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
29	Calcium signaling pathway 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
30	Calcium signaling pathway 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
31	Calcium signaling pathway 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
32	Calcium signaling pathway 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
33	Calcium signaling pathway 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
34	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
35	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
36	cAMP signaling pathway 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
37	cAMP signaling pathway 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
38	cAMP signaling pathway 💬	2件: ADRB1, ADRB2 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
39	cAMP signaling pathway 💬	2件: ADRB1, ADRB2 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
40	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
41	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
42	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
43	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
44	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
45	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
46	Cellular senescence 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
47	Cellular senescence 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
48	cGMP-PKG signaling pathway 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
49	cGMP-PKG signaling pathway 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
50	cGMP-PKG signaling pathway 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
51	cGMP-PKG signaling pathway 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
52	cGMP-PKG signaling pathway 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
53	cGMP-PKG signaling pathway 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
54	cGMP-PKG signaling pathway 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
55	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
56	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
57	Chagas disease 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
58	Chagas disease 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
59	Cholinergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
60	Cholinergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
61	Circadian entrainment 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
62	Circadian entrainment 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
63	Coronavirus disease - COVID-19 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
64	Coronavirus disease - COVID-19 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
65	Coronavirus disease - COVID-19 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
66	Coronavirus disease - COVID-19 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
67	Coronavirus disease - COVID-19 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
68	Cortisol synthesis and secretion 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
69	Cortisol synthesis and secretion 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
70	Cortisol synthesis and secretion 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
71	Cortisol synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
72	Cortisol synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
73	Cushing syndrome 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
74	Cushing syndrome 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
75	Cushing syndrome 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
76	Cushing syndrome 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
77	Cushing syndrome 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
78	Diabetic cardiomyopathy 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
79	Diabetic cardiomyopathy 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
80	Diabetic cardiomyopathy 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
81	Diabetic cardiomyopathy 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
82	Diabetic cardiomyopathy 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
83	Diabetic cardiomyopathy 💬	1件: REN 💬	D03208 💬	Aliskiren	4件: 66, 167, 222, 223 💬
84	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
85	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
86	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
87	Dilated cardiomyopathy 💬	1件: ADRB1 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
88	Dilated cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
89	Dilated cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
90	Dopaminergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
91	Dopaminergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
92	GABAergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
93	GABAergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
94	Gap junction 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
95	Gap junction 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
96	Gap junction 💬	1件: ADRB1 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
97	Gap junction 💬	1件: ADRB1 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
98	Glutamatergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
99	Glutamatergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
100	GnRH secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
101	GnRH secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
102	GnRH signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
103	GnRH signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
104	Growth hormone synthesis, secretion and action 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
105	Growth hormone synthesis, secretion and action 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
106	Hypertrophic cardiomyopathy 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
107	Hypertrophic cardiomyopathy 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
108	Hypertrophic cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
109	Hypertrophic cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
110	Insulin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
111	Insulin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
112	Long-term potentiation 💬	1件: CACNA1C 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
113	Long-term potentiation 💬	1件: CACNA1C 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
114	MAPK signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
115	MAPK signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
116	Neuroactive ligand-receptor interaction 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
117	Neuroactive ligand-receptor interaction 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
118	Neuroactive ligand-receptor interaction 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
119	Neuroactive ligand-receptor interaction 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
120	Neuroactive ligand-receptor interaction 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
121	Neuroactive ligand-receptor interaction 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
122	Neuroactive ligand-receptor interaction 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
123	Oxytocin signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
124	Oxytocin signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
125	Pathways in cancer 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
126	Pathways in cancer 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
127	Pathways in cancer 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
128	Pathways of neurodegeneration - multiple diseases 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
129	Pathways of neurodegeneration - multiple diseases 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
130	Phospholipase D signaling pathway 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
131	Phospholipase D signaling pathway 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
132	Phospholipase D signaling pathway 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
133	Prion disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
134	Prion disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
135	Regulation of lipolysis in adipocytes 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
136	Regulation of lipolysis in adipocytes 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
137	Regulation of lipolysis in adipocytes 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
138	Regulation of lipolysis in adipocytes 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
139	Renin secretion 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
140	Renin secretion 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
141	Renin secretion 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
142	Renin secretion 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
143	Renin secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
144	Renin secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
145	Renin secretion 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
146	Renin secretion 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
147	Renin secretion 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
148	Renin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
149	Renin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
150	Renin secretion 💬	1件: REN 💬	D03208 💬	Aliskiren	4件: 66, 167, 222, 223 💬
151	Renin-angiotensin system 💬	1件: ACE 💬	D00624 💬	Perindopril	3件: 113, 167, 222 💬
152	Renin-angiotensin system 💬	1件: ACE 💬	D03753 💬	Perindopril	3件: 113, 167, 222 💬
153	Renin-angiotensin system 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
154	Renin-angiotensin system 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
155	Renin-angiotensin system 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
156	Renin-angiotensin system 💬	1件: REN 💬	D03208 💬	Aliskiren	4件: 66, 167, 222, 223 💬
157	Retrograde endocannabinoid signaling 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
158	Retrograde endocannabinoid signaling 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
159	Salivary secretion 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
160	Salivary secretion 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
161	Salivary secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
162	Salivary secretion 💬	3件: ADRB1, ADRB2, ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
163	Serotonergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
164	Serotonergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
165	Taste transduction 💬	1件: CACNA1C 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
166	Taste transduction 💬	1件: CACNA1C 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
167	Thermogenesis 💬	1件: ADRB3 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
168	Thermogenesis 💬	1件: ADRB3 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
169	Tight junction 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
170	Tight junction 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
171	Type II diabetes mellitus 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
172	Type II diabetes mellitus 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
173	Vascular smooth muscle contraction 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
174	Vascular smooth muscle contraction 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
175	Vascular smooth muscle contraction 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
176	Vascular smooth muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
177	Vascular smooth muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬

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