DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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63 / 286 pathways

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	ABC transporters 💬	1件: ABCC8 💬	D00294 💬	Diazoxide	2件: 13, 193 💬
2	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D00601 💬	Metoprolol	6件: 17, 57, 58, 113, 193, 226 💬
3	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D02358 💬	Metoprolol	6件: 17, 57, 58, 113, 193, 226 💬
4	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D05011 💬	Metoprolol	6件: 17, 57, 58, 113, 193, 226 💬
5	Adrenergic signaling in cardiomyocytes 💬	5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
6	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
7	Aldosterone synthesis and secretion 💬	1件: MC2R 💬	D00146 💬	Corticotropin	13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
8	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
9	Amphetamine addiction 💬	6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
10	Amyotrophic lateral sclerosis 💬	2件: GRIA1, GRIA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬

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