DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
2	African trypanosomiasis 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
3	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
4	Alcoholism 💬	1件: DRD2 💬	D00799 💬	Trifluoperazine	2件: 283, 284 💬
5	Alcoholism 💬	1件: DRD2 💬	D01448 💬	Trifluoperazine	2件: 283, 284 💬
6	Alcoholism 💬	1件: DRD2 💬	D08636 💬	Trifluoperazine	2件: 283, 284 💬
7	Allograft rejection 💬	2件: CD80, CD86 💬	D03203 💬	Abatacept	26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
8	Allograft rejection 💬	1件: TNF 💬	D04687 💬	Lenalidomide	7件: 16, 26, 28, 34, 49, 284, 300 💬
9	Alzheimer disease 💬	1件: CASP9 💬	D11195 💬	Rimiducid	6件: 19, 60, 65, 284, 285, 326 💬
10	Alzheimer disease 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬

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