DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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26 / 286 pathways

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00680 💬	Methylergometrine	2件: 118, 288 💬
2	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08207 💬	Methylergometrine	2件: 118, 288 💬
3	Alzheimer disease 💬	1件: PSMB5 💬	D03150 💬	Bortezomib	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
4	AMPK signaling pathway 💬	1件: ADRA1A 💬	D00680 💬	Methylergometrine	2件: 118, 288 💬
5	AMPK signaling pathway 💬	1件: ADRA1A 💬	D08207 💬	Methylergometrine	2件: 118, 288 💬
6	AMPK signaling pathway 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
7	Amyotrophic lateral sclerosis 💬	1件: PSMB5 💬	D03150 💬	Bortezomib	15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
8	Bile secretion 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
9	Calcium signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D00680 💬	Methylergometrine	2件: 118, 288 💬
10	Calcium signaling pathway 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08207 💬	Methylergometrine	2件: 118, 288 💬

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