DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	2件: PML, RARA 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
2	Adherens junction 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
3	Adherens junction 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
4	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
5	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
6	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
7	African trypanosomiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
9	Allograft rejection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10	Alzheimer disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

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