1 |
Abatacept |
Abatacept |
[1] D03203 D03203 💬 |
CD80 [2] CD80, CD86 💬 |
Allograft rejection [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis |
011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
2 |
Actemra |
- |
- |
- |
- |
046 [2] 46, 107 💬 |
3 |
Actemra, mra |
- |
- |
- |
- |
107 [1] 107 💬 |
4 |
Acz885 |
- |
- |
- |
- |
046 [7] 46, 84, 106, 107, 108, 266, 267 💬 |
5 |
Acz885 150 mg (canakinumab) |
Canakinumab |
[1] D09315 D09315 💬 |
IL1B [1] IL1B 💬 |
AGE-RAGE signaling pathway in diabetic complications [42] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection |
107 [1] 107 💬 |
6 |
Acz885 drug substance |
- |
- |
- |
- |
046 [3] 46, 106, 107 💬 |
7 |
Acz885g |
- |
- |
- |
- |
107 [1] 107 💬 |
8 |
Anakinra |
Anakinra |
[1] D02934 D02934 💬 |
IL1R1 [2] IL1R1, IL1R2 💬 |
Amoebiasis [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer |
002 [17] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 84, 86, 97, 106, 107, 299 💬 |
9 |
Anakinra / kineret |
Anakinra |
[1] D02934 D02934 💬 |
IL1R1 [2] IL1R1, IL1R2 💬 |
Amoebiasis [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer |
107 [1] 107 💬 |
10 |
Apd421 |
- |
- |
- |
- |
107 [1] 107 💬 |
11 |
Baricitinib |
Baricitinib |
[1] D10308 D10308 💬 |
JAK1 [2] JAK1, JAK2 💬 |
AGE-RAGE signaling pathway in diabetic complications [33] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis |
041 [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
12 |
Canakinumab |
Canakinumab |
[1] D09315 D09315 💬 |
IL1B [1] IL1B 💬 |
AGE-RAGE signaling pathway in diabetic complications [42] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection |
046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
13 |
Ccp-690-550-10 |
- |
- |
- |
- |
107 [1] 107 💬 |
14 |
Corticosteroids |
- |
- |
- |
- |
041 [10] 41, 46, 49, 64, 97, 107, 164, 220, 296, 300 💬 |
15 |
Cp |
- |
- |
- |
- |
006 [6] 6 , 46, 96, 97, 107, 271 💬 |
16 |
Cp-690,550-10 |
- |
- |
- |
- |
046 [5] 46, 96, 97, 107, 271 💬 |
17 |
Css |
- |
- |
- |
- |
107 [1] 107 💬 |
18 |
Emapalumab |
Emapalumab |
[1] D11120 D11120 💬 |
IFNG [1] IFNG 💬 |
African trypanosomiasis [32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus |
107 [1] 107 💬 |
19 |
Fully human anti-interferon gamma monoclonal antibody |
Interferon Gamma |
- |
- |
- |
107 [1] 107 💬 |
20 |
Heparin |
Heparin |
[1] D07510 D07510 💬 |
SERPINC1 [1] SERPINC1 💬 |
Complement and coagulation cascades [1] Complement and coagulation cascades |
060 [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
21 |
Il-6 receptor inhibitor, recombinant humanized monoclonal antibody |
- |
- |
- |
- |
046 [2] 46, 107 💬 |
22 |
Ilaris |
- |
- |
- |
- |
056 [7] 56, 84, 106, 107, 108, 266, 267 💬 |
23 |
In double-blind phase: treatment with tofacitinib |
Tofacitinib |
[1] D09970 D09970 💬 |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
AGE-RAGE signaling pathway in diabetic complications [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis |
107 [1] 107 💬 |
24 |
In open-label phase: treatment with tofacitinib |
Tofacitinib |
[1] D09970 D09970 💬 |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
AGE-RAGE signaling pathway in diabetic complications [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis |
107 [1] 107 💬 |
25 |
Interferon gamma |
Interferon Gamma |
- |
- |
- |
018 [8] 18, 65, 85, 107, 228, 299, 301, 326 💬 |
26 |
Itf2357 |
- |
- |
- |
- |
096 [4] 96, 107, 113, 267 💬 |
27 |
Kineret |
- |
- |
- |
- |
028 [9] 28, 41, 46, 49, 65, 106, 107, 266, 299 💬 |
28 |
Kineret*sc 7sir 100mg 0,67ml |
- |
- |
- |
- |
028 [3] 28, 46, 107 💬 |
29 |
Kineret® or anakinra |
Anakinra |
[1] D02934 D02934 💬 |
IL1R1 [2] IL1R1, IL1R2 💬 |
Amoebiasis [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer |
107 [1] 107 💬 |
30 |
Ly3009104 |
- |
- |
- |
- |
046 [6] 46, 49, 50, 93, 107, 325 💬 |
31 |
Methotrexate |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
32 |
Mra |
- |
- |
- |
- |
046 [2] 46, 107 💬 |
33 |
Mra (actemra) |
- |
- |
- |
- |
107 [1] 107 💬 |
34 |
Mra (tocilizumab) |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
35 |
Mra(tocilizumab) |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
36 |
Mra, actemra |
- |
- |
- |
- |
046 [2] 46, 107 💬 |
37 |
Mtx |
- |
- |
- |
- |
035 [12] 35, 40, 46, 49, 50, 60, 84, 96, 97, 107, 162, 271 💬 |
38 |
Ni-0501 |
- |
- |
- |
- |
107 [1] 107 💬 |
39 |
Non-steroidal anti-inflammatory drugs (nsaids) |
- |
- |
- |
- |
107 [1] 107 💬 |
40 |
Nsaids |
- |
- |
- |
- |
046 [4] 46, 70, 107, 271 💬 |
41 |
Null |
- |
- |
- |
- |
006 [16] 6 , 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271 💬 |
42 |
Olumiant |
- |
- |
- |
- |
046 [4] 46, 49, 93, 107 💬 |
43 |
Pneumo23 |
- |
- |
- |
- |
107 [1] 107 💬 |
44 |
Recombinant antihumanized anti-human monoclonal antibody directed against the il-6r |
- |
- |
- |
- |
107 [1] 107 💬 |
45 |
Recombinant human monoclonal antibody to human il-1beta of the igg1/k class |
- |
- |
- |
- |
106 [3] 106, 107, 108 💬 |
46 |
Regn88 |
Sarilumab |
[1] D10161 D10161 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
47 |
Ril-1ra |
- |
- |
- |
- |
107 [1] 107 💬 |
48 |
Rilonacept |
Rilonacept |
[1] D06635 D06635 💬 |
IL1A [2] IL1A, IL1B 💬 |
AGE-RAGE signaling pathway in diabetic complications [43] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection |
051 [4] 51, 106, 107, 266 💬 |
49 |
Rilonacept (il-1 trap) |
Rilonacept |
[1] D06635 D06635 💬 |
IL1A [2] IL1A, IL1B 💬 |
AGE-RAGE signaling pathway in diabetic complications [43] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection |
107 [1] 107 💬 |
50 |
Ro 487-7533/f10-04 |
- |
- |
- |
- |
041 [4] 41, 46, 51, 107 💬 |
51 |
Ro4877533 (tcz) |
- |
- |
- |
- |
046 [2] 46, 107 💬 |
52 |
Roactemra |
- |
- |
- |
- |
040 [9] 40, 41, 46, 51, 86, 107, 266, 271, 331 💬 |
53 |
Sar153191 |
Sarilumab |
[1] D10161 D10161 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
041 [4] 41, 46, 107, 271 💬 |
54 |
Sar153191 (regn88) |
Sarilumab |
[1] D10161 D10161 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
55 |
Sarilumab |
Sarilumab |
[1] D10161 D10161 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
041 [5] 41, 46, 84, 107, 271 💬 |
56 |
Sarilumab sar153191 (regn88) |
Sarilumab |
[1] D10161 D10161 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
57 |
Tocilizumab |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
58 |
Tocilizumab [roactemra/actemra] |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [4] 46, 51, 107, 331 💬 |
59 |
Tocilizumab roche |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [2] 46, 107 💬 |
60 |
Tocilizumab sc |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
041 [3] 41, 46, 107 💬 |
61 |
Tofacitinib |
Tofacitinib |
[1] D09970 D09970 💬 |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
AGE-RAGE signaling pathway in diabetic complications [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis |
011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
62 |
Tofacitinib citrate |
Tofacitinib |
[1] D09970 D09970 💬 |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
AGE-RAGE signaling pathway in diabetic complications [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis |
046 [5] 46, 49, 97, 107, 271 💬 |
63 |
Tofacitinibe citrate |
- |
- |
- |
- |
107 [1] 107 💬 |