1 |
5009111000001105 |
- |
- |
- |
- |
043 [1] 43 💬 |
2 |
Alemtuzumab |
Alemtuzumab |
[1] D02802 D02802 💬 |
- |
- |
013 [16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬 |
3 |
Avacopan |
Avacopan |
[1] D11093 D11093 💬 |
C5AR1 [1] C5AR1 💬 |
Complement and coagulation cascades [5] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection |
043 [4] 43, 44, 222, 223 💬 |
4 |
Azathioprine |
Azathioprine |
[2] D00238 D00238, D03033 D03033 💬 |
- |
- |
006 [20] 6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬 |
5 |
Belimumab |
Belimumab |
[1] D03068 D03068 💬 |
TNFSF13B [1] TNFSF13B 💬 |
Cytokine-cytokine receptor interaction [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis |
011 [10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬 |
6 |
Belimumab 10 mg/kg |
Belimumab |
[1] D03068 D03068 💬 |
TNFSF13B [1] TNFSF13B 💬 |
Cytokine-cytokine receptor interaction [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis |
043 [3] 43, 46, 49 💬 |
7 |
Benlysta |
- |
- |
- |
- |
043 [5] 43, 49, 53, 66, 222 💬 |
8 |
Benlysta 400 mg powder for concentrate for solution for infusion |
- |
- |
- |
- |
043 [2] 43, 49 💬 |
9 |
Benlysta 400mg polvere per concentrato per soluzione per infusione |
- |
- |
- |
- |
043 [1] 43 💬 |
10 |
Blisibimod |
Blisibimod |
[1] D10311 D10311 💬 |
- |
- |
043 [5] 43, 44, 49, 63, 66 💬 |
11 |
Ccx168 |
- |
- |
- |
- |
043 [6] 43, 44, 66, 109, 222, 223 💬 |
12 |
Cellcept |
- |
- |
- |
- |
011 [5] 11, 13, 42, 43, 49 💬 |
13 |
Cellcept (mycophenolate mofetil) |
Mycophenolate mofetil |
[4] D00752 D00752, D05094 D05094, D05095 D05095, D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
042 [2] 42, 43 💬 |
14 |
Chimeric monoclonal antibody, igg4 subtype |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
15 |
Corticosteroid |
- |
- |
- |
- |
013 [10] 13, 42, 43, 44, 45, 66, 84, 96, 97, 222 💬 |
16 |
Corticosteroid and azathioprine |
Azathioprine |
[2] D00238 D00238, D03033 D03033 💬 |
- |
- |
042 [4] 42, 43, 44, 45 💬 |
17 |
Cyclophosphamide |
Cyclophosphamide |
[2] D00287 D00287, D07760 D07760 💬 |
- |
- |
011 [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 |
18 |
Cyclophosphamide, azathioprine,prednisone,methylprednisolone |
Azathioprine |
[11] D00238 D00238, D00287 D00287, D00407 D00407, D00473 D00473, D00751 D00751, D00979 D00979, D03033 D03033, D05000 D05000, D05001 D05001, D05002 D05002, D07760 D07760 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
042 [3] 42, 43, 45 💬 |
19 |
Deltacortene |
- |
- |
- |
- |
043 [2] 43, 97 💬 |
20 |
Endoxan |
- |
- |
- |
- |
013 [7] 13, 28, 43, 44, 85, 96, 222 💬 |
21 |
Endoxan baxter |
- |
- |
- |
- |
013 [3] 13, 43, 96 💬 |
22 |
Freeze-dried sulfonated human normal immunoglobulin (ggs) |
Human immunoglobulin G |
- |
- |
- |
014 [3] 14, 43, 45 💬 |
23 |
Galen® tablet |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
24 |
Glucocorticoid (gc) |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
25 |
Glucocorticoids |
- |
- |
- |
- |
040 [8] 40, 41, 43, 44, 60, 62, 75, 300 💬 |
26 |
Glucocorticoids (gc) |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
27 |
Glucocorticoids - reduced dose |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
28 |
Glucocorticoids - standard dose |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
29 |
Glucocorticoids [reduced dose] |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
30 |
Glucocorticoids [standard dose] |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
31 |
Human normal immunoglobulin |
Human immunoglobulin G |
- |
- |
- |
011 [9] 11, 13, 14, 43, 45, 50, 51, 63, 65 💬 |
32 |
Hydroxychloroquine |
Hydroxychloroquine |
[1] D08050 D08050 💬 |
- |
- |
013 [23] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 218, 222, 234, 254, 271, 298, 299 💬 |
33 |
Ifx-1 |
- |
- |
- |
- |
043 [3] 43, 44, 269 💬 |
34 |
Infliximab |
Infliximab |
[1] D02598 D02598 💬 |
TNF [1] TNF 💬 |
AGE-RAGE signaling pathway in diabetic complications [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway |
035 [24] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
35 |
Intravenous immunoglobulins (human immunoglobulins g) |
- |
- |
- |
- |
043 [1] 43 💬 |
36 |
Intravenous methyl prednisolone |
Prednisolone |
[8] D00472 D00472, D00980 D00980, D00981 D00981, D00982 D00982, D01239 D01239, D01998 D01998, D02156 D02156, D03301 D03301 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
043 [1] 43 💬 |
37 |
Mabthera |
- |
- |
- |
- |
011 [22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271 💬 |
38 |
Mabthera® |
- |
- |
- |
- |
013 [6] 13, 35, 43, 44, 46, 93 💬 |
39 |
Mabthera® 100mg |
- |
- |
- |
- |
043 [1] 43 💬 |
40 |
Mabthera® 500mg |
- |
- |
- |
- |
043 [1] 43 💬 |
41 |
Methotrexate |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
42 |
Methyl prednisolone |
Prednisolone |
[8] D00472 D00472, D00980 D00980, D00981 D00981, D00982 D00982, D01239 D01239, D01998 D01998, D02156 D02156, D03301 D03301 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
043 [3] 43, 49, 96 💬 |
43 |
Methylprednisolone |
Methylprednisolone |
[6] D00407 D00407, D00751 D00751, D00979 D00979, D05000 D05000, D05001 D05001, D05002 D05002 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
44 |
Methylprednisolone (or other glucocorticoid) |
Methylprednisolone |
[6] D00407 D00407, D00751 D00751, D00979 D00979, D05000 D05000, D05001 D05001, D05002 D05002 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
043 [1] 43 💬 |
45 |
Mycophenolate |
Mycophenolic acid |
[1] D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
46 |
Mycophenolate mofetil |
Mycophenolate mofetil |
[4] D00752 D00752, D05094 D05094, D05095 D05095, D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
47 |
Mycophenolate mofetil,methotrexate |
Methotrexate |
[6] D00142 D00142, D00752 D00752, D02115 D02115, D05094 D05094, D05095 D05095, D05096 D05096 💬 |
DHFR [4] DHFR, DHFR2, IMPDH1, IMPDH2 💬 |
Antifolate resistance [7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism |
042 [3] 42, 43, 45 💬 |
48 |
Mycophenolic acid |
Mycophenolic acid |
[1] D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
011 [8] 11, 43, 49, 51, 60, 66, 96, 222 💬 |
49 |
Naltrexone |
Naltrexone |
[2] D02095 D02095, D05113 D05113 💬 |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
Estrogen signaling pathway [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
006 [12] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬 |
50 |
Naltrexone hydrochloride |
Naltrexone |
[2] D02095 D02095, D05113 D05113 💬 |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
Estrogen signaling pathway [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
010 [8] 10, 40, 41, 42, 43, 44, 45, 96 💬 |
51 |
Other: no plasma exchange |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
52 |
Pednisone |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
53 |
Placebo (physiological saline) |
- |
- |
- |
- |
043 [2] 43, 45 💬 |
54 |
Plaquenil - hydroxychloroquine 200mg film coated tablets |
Hydroxychloroquine |
[1] D08050 D08050 💬 |
- |
- |
043 [3] 43, 44, 45 💬 |
55 |
Prednisolone |
Prednisolone |
[8] D00472 D00472, D00980 D00980, D00981 D00981, D00982 D00982, D01239 D01239, D01998 D01998, D02156 D02156, D03301 D03301 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
56 |
Prednison acis® 20 mg |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
57 |
Prednison acis® 5 mg |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
58 |
Prednisone |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
59 |
Prednisone (and methylprednisolone) |
Methylprednisolone |
[7] D00407 D00407, D00473 D00473, D00751 D00751, D00979 D00979, D05000 D05000, D05001 D05001, D05002 D05002 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
043 [1] 43 💬 |
60 |
Prednisone tablets, usp |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
041 [3] 41, 43, 44 💬 |
61 |
Prednisone, methylprednisolone,cyclophosphamides |
Methylprednisolone |
[7] D00407 D00407, D00473 D00473, D00751 D00751, D00979 D00979, D05000 D05000, D05001 D05001, D05002 D05002 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
042 [3] 42, 43, 45 💬 |
62 |
Procedure: plasma exchange |
- |
- |
- |
- |
013 [5] 13, 43, 44, 64, 222 💬 |
63 |
Remission induction therapy |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
64 |
Rituximab |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
011 [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
65 |
Rituximab (arm a) |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
043 [2] 43, 44 💬 |
66 |
Rituximab (arm b) |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
043 [2] 43, 44 💬 |
67 |
Rixathon 500mg |
- |
- |
- |
- |
043 [1] 43 💬 |
68 |
Ro0452294/v01 |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
69 |
Ro0452294/v02 |
- |
- |
- |
- |
035 [3] 35, 43, 44 💬 |
70 |
Ro106-1443 |
- |
- |
- |
- |
043 [1] 43 💬 |
71 |
Sendoxan |
- |
- |
- |
- |
013 [2] 13, 43 💬 |
72 |
Tocilizumab |
Tocilizumab |
[1] D02596 D02596 💬 |
IL6R [1] IL6R 💬 |
Coronavirus disease - COVID-19 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
73 |
Vitamin d |
Vitamin D |
- |
- |
- |
013 [21] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 274, 298, 299 💬 |