1 |
0 mg prednisone |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
044 [1] 44 💬 |
2 |
5 mg prednisone |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
044 [1] 44 💬 |
3 |
Abatacept |
Abatacept |
[1] D03203 D03203 💬 |
CD80 [2] CD80, CD86 💬 |
Allograft rejection [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis |
011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
4 |
Abatacept (ctla4-ig) |
Abatacept |
[1] D03203 D03203 💬 |
CD80 [2] CD80, CD86 💬 |
Allograft rejection [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis |
044 [1] 44 💬 |
5 |
Alemtuzumab |
Alemtuzumab |
[1] D02802 D02802 💬 |
- |
- |
013 [16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬 |
6 |
Avacopan |
Avacopan |
[1] D11093 D11093 💬 |
C5AR1 [1] C5AR1 💬 |
Complement and coagulation cascades [5] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection |
043 [4] 43, 44, 222, 223 💬 |
7 |
Azathioprin-ratiopharm® 25 mg filmtabletten |
- |
- |
- |
- |
044 [1] 44 💬 |
8 |
Azathioprine |
Azathioprine |
[2] D00238 D00238, D03033 D03033 💬 |
- |
- |
006 [20] 6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬 |
9 |
Azathioprine 25 mg |
Azathioprine |
[2] D00238 D00238, D03033 D03033 💬 |
- |
- |
044 [1] 44 💬 |
10 |
Azd7986 |
- |
- |
- |
- |
044 [2] 44, 299 💬 |
11 |
Belimumab |
Belimumab |
[1] D03068 D03068 💬 |
TNFSF13B [1] TNFSF13B 💬 |
Cytokine-cytokine receptor interaction [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis |
011 [10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬 |
12 |
Benralizumab |
Benralizumab |
[1] D09874 D09874 💬 |
IL5RA [1] IL5RA 💬 |
Cytokine-cytokine receptor interaction [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer |
044 [4] 44, 45, 98, 162 💬 |
13 |
Biological: benralizumab, biological: placebo to mepolizumab |
Benralizumab |
[2] D04923 D04923, D09874 D09874 💬 |
IL5 [2] IL5, IL5RA 💬 |
Allograft rejection [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation |
044 [1] 44 💬 |
14 |
Biological: mepolizumab, biological: placebo to benralizumab |
Benralizumab |
[2] D04923 D04923, D09874 D09874 💬 |
IL5 [2] IL5, IL5RA 💬 |
Allograft rejection [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation |
044 [1] 44 💬 |
15 |
Blisibimod |
Blisibimod |
[1] D10311 D10311 💬 |
- |
- |
043 [5] 43, 44, 49, 63, 66 💬 |
16 |
Ccx168 |
- |
- |
- |
- |
043 [6] 43, 44, 66, 109, 222, 223 💬 |
17 |
Chimeric monoclonal antibody, igg4 subtype |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
18 |
Corticosteroid |
- |
- |
- |
- |
013 [10] 13, 42, 43, 44, 45, 66, 84, 96, 97, 222 💬 |
19 |
Corticosteroid and azathioprine |
Azathioprine |
[2] D00238 D00238, D03033 D03033 💬 |
- |
- |
042 [4] 42, 43, 44, 45 💬 |
20 |
Cyclophosphamide |
Cyclophosphamide |
[2] D00287 D00287, D07760 D07760 💬 |
- |
- |
011 [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 |
21 |
Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids |
Azathioprine |
[6] D00142 D00142, D00238 D00238, D00287 D00287, D02115 D02115, D03033 D03033, D07760 D07760 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
044 [1] 44 💬 |
22 |
Cyclophosphamidum |
Cyclophosphamide |
[2] D00287 D00287, D07760 D07760 💬 |
- |
- |
044 [1] 44 💬 |
23 |
Cyclophosphamidum 500 mg |
Cyclophosphamide |
[2] D00287 D00287, D07760 D07760 💬 |
- |
- |
044 [1] 44 💬 |
24 |
Endoxan |
- |
- |
- |
- |
013 [7] 13, 28, 43, 44, 85, 96, 222 💬 |
25 |
Endoxan® 500 mg |
- |
- |
- |
- |
044 [1] 44 💬 |
26 |
Galen® tablet |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
27 |
Glucocorticoid (gc) |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
28 |
Glucocorticoids |
- |
- |
- |
- |
040 [8] 40, 41, 43, 44, 60, 62, 75, 300 💬 |
29 |
Glucocorticoids (gc) |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
30 |
Glucocorticoids - reduced dose |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
31 |
Glucocorticoids - standard dose |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
32 |
Glucocorticoids [reduced dose] |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
33 |
Glucocorticoids [standard dose] |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
34 |
Gusperimus |
Gusperimus |
[1] D08032 D08032 💬 |
- |
- |
044 [1] 44 💬 |
35 |
Gusperimus + glucocorticoids |
Gusperimus |
[1] D08032 D08032 💬 |
- |
- |
044 [1] 44 💬 |
36 |
Hydroxychloroquine |
Hydroxychloroquine |
[1] D08050 D08050 💬 |
- |
- |
013 [23] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 218, 222, 234, 254, 271, 298, 299 💬 |
37 |
Ifx-1 |
- |
- |
- |
- |
043 [3] 43, 44, 269 💬 |
38 |
Ins1007 |
- |
- |
- |
- |
044 [2] 44, 299 💬 |
39 |
L04ac06 |
- |
- |
- |
- |
044 [2] 44, 45 💬 |
40 |
Mabthera |
- |
- |
- |
- |
011 [22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271 💬 |
41 |
Mabthera® |
- |
- |
- |
- |
013 [6] 13, 35, 43, 44, 46, 93 💬 |
42 |
Medi-563 |
- |
- |
- |
- |
044 [3] 44, 45, 98 💬 |
43 |
Mepolizumab |
Mepolizumab |
[1] D04923 D04923 💬 |
IL5 [1] IL5 💬 |
Allograft rejection [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation |
044 [4] 44, 45, 98, 162 💬 |
44 |
Mesna |
- |
- |
- |
- |
011 [11] 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬 |
45 |
Metex 2,5 mg tabletten |
- |
- |
- |
- |
044 [1] 44 💬 |
46 |
Methotrexate |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
47 |
Methotrexate 2.5 mg |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
044 [1] 44 💬 |
48 |
Methotrexate 25 mg |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
044 [1] 44 💬 |
49 |
Metoject 10 mg/ml, solution injectable en seringue pré-remplie |
- |
- |
- |
- |
044 [1] 44 💬 |
50 |
Naltrexone |
Naltrexone |
[2] D02095 D02095, D05113 D05113 💬 |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
Estrogen signaling pathway [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
006 [12] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬 |
51 |
Naltrexone hydrochloride |
Naltrexone |
[2] D02095 D02095, D05113 D05113 💬 |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
Estrogen signaling pathway [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
010 [8] 10, 40, 41, 42, 43, 44, 45, 96 💬 |
52 |
Nucala |
- |
- |
- |
- |
044 [2] 44, 45 💬 |
53 |
Nucala 100 mg powder for solution for injection |
- |
- |
- |
- |
044 [2] 44, 45 💬 |
54 |
Orencia |
- |
- |
- |
- |
044 [13] 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 160, 222, 271 💬 |
55 |
Other: no plasma exchange |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
56 |
Pednisone |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
57 |
Plaquenil - hydroxychloroquine 200mg film coated tablets |
Hydroxychloroquine |
[1] D08050 D08050 💬 |
- |
- |
043 [3] 43, 44, 45 💬 |
58 |
Prednisolone |
Prednisolone |
[8] D00472 D00472, D00980 D00980, D00981 D00981, D00982 D00982, D01239 D01239, D01998 D01998, D02156 D02156, D03301 D03301 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
59 |
Prednison acis® 20 mg |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
60 |
Prednison acis® 5 mg |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
61 |
Prednisone |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
62 |
Prednisone tablets, usp |
Prednisone |
[1] D00473 D00473 💬 |
NR3C1 [1] NR3C1 💬 |
Neuroactive ligand-receptor interaction [1] Neuroactive ligand-receptor interaction |
041 [3] 41, 43, 44 💬 |
63 |
Procedure: plasma exchange |
- |
- |
- |
- |
013 [5] 13, 43, 44, 64, 222 💬 |
64 |
Recombinant humanized monoclonal antibody specific for human il-5 |
- |
- |
- |
- |
044 [1] 44 💬 |
65 |
Remission induction therapy |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
66 |
Reslizumab |
Reslizumab |
[1] D08985 D08985 💬 |
IL5 [1] IL5 💬 |
Allograft rejection [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation |
044 [2] 44, 98 💬 |
67 |
Rituximab |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
011 [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
68 |
Rituximab (arm a) |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
043 [2] 43, 44 💬 |
69 |
Rituximab (arm b) |
Rituximab |
[1] D02994 D02994 💬 |
MS4A1 [1] MS4A1 💬 |
Hematopoietic cell lineage [1] Hematopoietic cell lineage |
043 [2] 43, 44 💬 |
70 |
Ro0452294/v01 |
- |
- |
- |
- |
043 [2] 43, 44 💬 |
71 |
Ro0452294/v02 |
- |
- |
- |
- |
035 [3] 35, 43, 44 💬 |
72 |
Sb-240563 |
- |
- |
- |
- |
044 [3] 44, 45, 98 💬 |
73 |
Sb-240563 (mepolizumab) |
Mepolizumab |
[1] D04923 D04923 💬 |
IL5 [1] IL5 💬 |
Allograft rejection [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation |
044 [2] 44, 45 💬 |
74 |
Sulfamethoxazole |
Sulfamethoxazole |
[1] D00447 D00447 💬 |
- |
- |
044 [4] 44, 49, 85, 299 💬 |
75 |
Trimethoprim |
Trimethoprim |
[2] D00145 D00145, D06236 D06236 💬 |
- |
- |
036 [6] 36, 44, 49, 60, 85, 299 💬 |
76 |
Trimethoprim sulfamethoxazole |
Sulfamethoxazole |
[3] D00145 D00145, D00447 D00447, D06236 D06236 💬 |
- |
- |
044 [1] 44 💬 |
77 |
Vitamin d |
Vitamin D |
- |
- |
- |
013 [21] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 274, 298, 299 💬 |
78 |
Yellow fever vaccine |
Yellow Fever Vaccine |
[1] D06347 D06347 💬 |
- |
- |
040 [7] 40, 44, 46, 50, 51, 52, 53 💬 |
79 |
Yellow fever vaccine (17d) |
Yellow Fever Vaccine |
[1] D06347 D06347 💬 |
- |
- |
040 [7] 40, 44, 46, 50, 51, 52, 53 💬 |