1 |
Abp 959 |
- |
- |
- |
- |
062 [1] 62 💬 |
2 |
Abp 959 - biosimilar to eculizumab |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
3 |
Abp 959 - proposed biosimilar to eculizumab |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
4 |
Ach-0144471 |
- |
- |
- |
- |
062 [3] 62, 222, 223 💬 |
5 |
Ach-0145228 |
- |
- |
- |
- |
062 [1] 62 💬 |
6 |
Aln-62643 |
- |
- |
- |
- |
062 [1] 62 💬 |
7 |
Aln-cc5 |
- |
- |
- |
- |
062 [3] 62, 66, 109 💬 |
8 |
Alxn1102 |
- |
- |
- |
- |
062 [1] 62 💬 |
9 |
Alxn1103 |
- |
- |
- |
- |
062 [1] 62 💬 |
10 |
Alxn1210 |
- |
- |
- |
- |
002 [5] 2 , 11, 13, 62, 109 💬 |
11 |
Alxn2040 (ach-0144471) |
- |
- |
- |
- |
062 [2] 62, 222 💬 |
12 |
Alxn2050 |
- |
- |
- |
- |
062 [1] 62 💬 |
13 |
Anti-c5 antibody |
- |
- |
- |
- |
011 [4] 11, 14, 62, 109 💬 |
14 |
Anti-thymocyte globulin |
- |
- |
- |
- |
011 [18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬 |
15 |
Apl-2 |
- |
- |
- |
- |
061 [5] 61, 62, 66, 222, 223 💬 |
16 |
Bcd-148 |
- |
- |
- |
- |
062 [1] 62 💬 |
17 |
Bcx9930 |
- |
- |
- |
- |
062 [1] 62 💬 |
18 |
Bcx9930 hydrochloride |
- |
- |
- |
- |
062 [1] 62 💬 |
19 |
Bryostatin 1 |
Bryostatin 1 |
- |
- |
- |
062 [1] 62 💬 |
20 |
C5 inh mab, sky59, ro/ch7092230 |
- |
- |
- |
- |
062 [1] 62 💬 |
21 |
C5 inhibitor |
- |
- |
- |
- |
062 [1] 62 💬 |
22 |
C5 inhibitor background therapy |
- |
- |
- |
- |
062 [1] 62 💬 |
23 |
Campath |
- |
- |
- |
- |
019 [12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326 💬 |
24 |
Campath, chemo and/or tbi allo sct |
- |
- |
- |
- |
060 [3] 60, 62, 283 💬 |
25 |
Coversin |
Nomacopan |
[1] D11473 D11473 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [2] 62, 109 💬 |
26 |
Crovalimab |
Crovalimab |
[1] D11696 D11696 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
27 |
Cyclophosphamide |
Cyclophosphamide |
[2] D00287 D00287, D07760 D07760 💬 |
- |
- |
011 [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 |
28 |
Cyclosporin |
Cyclosporine |
[1] D00184 D00184 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
038 [17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326 💬 |
29 |
Cyclosporin a |
Cyclosporine |
[1] D00184 D00184 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
046 [11] 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164 💬 |
30 |
Cyclosporin a+glucocorticoids |
Cyclosporine |
[1] D00184 D00184 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
060 [2] 60, 62 💬 |
31 |
Cyclosporine |
Cyclosporine |
[1] D00184 D00184 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
011 [35] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬 |
32 |
Cytoreductive regimen followed by a cd34+e- selected allogeneic stem cell transplant |
- |
- |
- |
- |
062 [1] 62 💬 |
33 |
Danicopan |
Danicopan |
[1] D11641 D11641 💬 |
CFD [1] CFD 💬 |
Complement and coagulation cascades [3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection |
062 [2] 62, 222 💬 |
34 |
Danicopan (alxn2040) |
Danicopan |
[1] D11641 D11641 💬 |
CFD [1] CFD 💬 |
Complement and coagulation cascades [3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection |
062 [1] 62 💬 |
35 |
Device: miltenyi biotec clinimacs |
- |
- |
- |
- |
062 [2] 62, 326 💬 |
36 |
Device: miltenyi clinimacs |
- |
- |
- |
- |
062 [2] 62, 65 💬 |
37 |
Dextran |
Dextran |
[1] D00060 D00060 💬 |
- |
- |
002 [5] 2 , 62, 79, 96, 97 💬 |
38 |
Eculizumab |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
39 |
Elizaria® |
- |
- |
- |
- |
062 [1] 62 💬 |
40 |
Fc- and cdr-modified humanised monoclonal antibody against c5 |
- |
- |
- |
- |
011 [3] 11, 62, 109 💬 |
41 |
Filgrastim |
Filgrastim |
[1] D03235 D03235 💬 |
CSF3R [1] CSF3R 💬 |
Cytokine-cytokine receptor interaction [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer |
002 [27] 2 , 6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
42 |
Fludarabine |
Fludarabine |
[2] D01907 D01907, D07966 D07966 💬 |
RRM1 [1] RRM1 💬 |
Drug metabolism - other enzymes [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
013 [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
43 |
Fludarabine phosphate |
Fludarabine |
[2] D01907 D01907, D07966 D07966 💬 |
RRM1 [1] RRM1 💬 |
Drug metabolism - other enzymes [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
028 [11] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285 💬 |
44 |
G-csf |
Filgrastim |
[1] D03235 D03235 💬 |
CSF3R [1] CSF3R 💬 |
Cytokine-cytokine receptor interaction [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer |
002 [16] 2 , 6 , 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331 💬 |
45 |
Glucocorticoids |
- |
- |
- |
- |
040 [8] 40, 41, 43, 44, 60, 62, 75, 300 💬 |
46 |
H5g1.1-mab |
- |
- |
- |
- |
013 [3] 13, 50, 62 💬 |
47 |
Human monoclonal antibody directed against complement 5 protein |
- |
- |
- |
- |
062 [1] 62 💬 |
48 |
Iron dextran |
Dextran |
[2] D00060 D00060, D02141 D02141 💬 |
- |
- |
062 [1] 62 💬 |
49 |
Iron sucrose |
Iron sucrose |
[2] D00025 D00025, D04616 D04616 💬 |
- |
- |
062 [3] 62, 96, 97 💬 |
50 |
L04aa25 |
- |
- |
- |
- |
062 [1] 62 💬 |
51 |
Levamisole |
Levamisole |
[2] D00750 D00750, D08114 D08114 💬 |
- |
- |
060 [3] 60, 61, 62 💬 |
52 |
Levamisole+cyclosporin a+glucocorticoids |
Cyclosporine |
[3] D00184 D00184, D00750 D00750, D08114 D08114 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
060 [2] 60, 62 💬 |
53 |
Lfg316 |
- |
- |
- |
- |
062 [1] 62 💬 |
54 |
Lnp023 |
- |
- |
- |
- |
062 [3] 62, 66, 222 💬 |
55 |
Melphalan |
Melphalan |
[1] D00369 D00369 💬 |
- |
- |
011 [15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬 |
56 |
Methotrexate |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
57 |
Mycophenolate |
Mycophenolic acid |
[1] D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
58 |
Mycophenolate mofetil |
Mycophenolate mofetil |
[4] D00752 D00752, D05094 D05094, D05095 D05095, D05096 D05096 💬 |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Drug metabolism - other enzymes [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
59 |
Myeloablative preparative regimen |
- |
- |
- |
- |
062 [3] 62, 65, 284 💬 |
60 |
No |
- |
- |
- |
- |
046 [3] 46, 62, 299 💬 |
61 |
Other: blood collection for measurement of eculizumab peak concentrations |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
62 |
Other: laboratory biomarker analysis |
- |
- |
- |
- |
011 [21] 11, 13, 14, 16, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 232, 283, 284, 285, 298, 331 💬 |
63 |
Other: pharmacological study |
- |
- |
- |
- |
028 [7] 28, 34, 62, 74, 89, 232, 331 💬 |
64 |
Other: standard of care (soc) |
- |
- |
- |
- |
062 [1] 62 💬 |
65 |
Pegcetacoplan |
- |
- |
- |
- |
062 [2] 62, 222 💬 |
66 |
Pegcetacoplan (apl-2) |
- |
- |
- |
- |
002 [2] 2 , 62 💬 |
67 |
Phosphate |
Phosphate ion |
- |
- |
- |
002 [30] 2 , 3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬 |
68 |
Procedure: allogeneic hematopoietic stem cell transplantation |
- |
- |
- |
- |
028 [8] 28, 51, 60, 62, 65, 164, 284, 285 💬 |
69 |
Procedure: allogeneic stem cell transplantation |
- |
- |
- |
- |
019 [3] 19, 20, 62 💬 |
70 |
Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation |
- |
- |
- |
- |
028 [6] 28, 51, 60, 62, 65, 285 💬 |
71 |
Procedure: peripheral blood stem cell transplantation |
- |
- |
- |
- |
011 [11] 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285 💬 |
72 |
Procedure: stem cell transplantation |
- |
- |
- |
- |
019 [6] 19, 51, 60, 62, 65, 326 💬 |
73 |
Ra101495 |
- |
- |
- |
- |
062 [1] 62 💬 |
74 |
Ra101495 sodium |
- |
- |
- |
- |
062 [1] 62 💬 |
75 |
Radiation: total-body irradiation |
- |
- |
- |
- |
028 [9] 28, 51, 60, 62, 65, 96, 283, 284, 285 💬 |
76 |
Ravulizumab |
Ravulizumab |
[1] D11054 D11054 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
002 [5] 2 , 11, 13, 62, 109 💬 |
77 |
Reduced intensity preparative regimen |
- |
- |
- |
- |
062 [3] 62, 65, 284 💬 |
78 |
Reduced toxicity ablative regimen |
- |
- |
- |
- |
062 [3] 62, 65, 284 💬 |
79 |
Regn3918 |
- |
- |
- |
- |
062 [1] 62 💬 |
80 |
Ro7112689 |
- |
- |
- |
- |
062 [1] 62 💬 |
81 |
Ro7112689/f01 |
- |
- |
- |
- |
062 [1] 62 💬 |
82 |
Ro7112689/f03-01 |
- |
- |
- |
- |
062 [1] 62 💬 |
83 |
Ro7112689/f03-03 |
- |
- |
- |
- |
062 [1] 62 💬 |
84 |
Rva576 |
- |
- |
- |
- |
062 [3] 62, 109, 162 💬 |
85 |
Rva576 (coversin) |
Nomacopan |
[1] D11473 D11473 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [2] 62, 109 💬 |
86 |
Sargramostim |
Sargramostim |
[1] D05803 D05803 💬 |
CSF2RA [1] CSF2RA 💬 |
Cytokine-cytokine receptor interaction [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer |
006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
87 |
Sb12 (proposed eculizumab biosimilar) |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
88 |
Sirolimus |
Sirolimus |
[1] D00753 D00753 💬 |
MTOR [1] MTOR 💬 |
AMPK signaling pathway [50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway |
006 [35] 6 , 13, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
89 |
Soliris |
- |
- |
- |
- |
011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
90 |
Soliris (eculizumab) |
Eculizumab |
[1] D03940 D03940 💬 |
C5 [1] C5 💬 |
Complement and coagulation cascades [9] Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus |
062 [1] 62 💬 |
91 |
Soliris 300 |
- |
- |
- |
- |
062 [1] 62 💬 |
92 |
Soliris® |
- |
- |
- |
- |
062 [1] 62 💬 |
93 |
Sterile normal saline (0.9% nacl) |
- |
- |
- |
- |
062 [3] 62, 234, 254 💬 |
94 |
Sucrose |
Sucrose |
[1] D00025 D00025 💬 |
- |
- |
062 [3] 62, 96, 97 💬 |
95 |
Synthetic 15-amino-acid macrocyclic peptide |
- |
- |
- |
- |
062 [1] 62 💬 |
96 |
Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 |
- |
- |
- |
- |
062 [1] 62 💬 |
97 |
Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 palmitoylated linker |
- |
- |
- |
- |
062 [1] 62 💬 |
98 |
Synthetic 15-amino-acid macrocyclic peptide acylated with a polyethyleneglycol palmitoylated linker |
- |
- |
- |
- |
062 [1] 62 💬 |
99 |
Systematic chemotherapy and antibodies |
- |
- |
- |
- |
062 [1] 62 💬 |
100 |
Systemic chemotherapy and antibodies |
- |
- |
- |
- |
062 [2] 62, 326 💬 |
101 |
Tacrolimus |
Tacrolimus |
[2] D00107 D00107, D08556 D08556 💬 |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Alzheimer disease [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
102 |
Ultomiris |
- |
- |
- |
- |
002 [4] 2 , 11, 13, 62 💬 |
103 |
Vari |
- |
- |
- |
- |
062 [2] 62, 274 💬 |
104 |
Zilucoplan |
Zilucoplan |
- |
- |
- |
002 [3] 2 , 11, 62 💬 |
105 |
Zilucoplan (ra101495) |
Zilucoplan |
- |
- |
- |
011 [2] 11, 62 💬 |
106 |
lnp023 hydrochloride salt |
- |
- |
- |
- |
062 [3] 62, 66, 222 💬 |