1 |
150-mg ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
2 |
150mg ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
3 |
Cf patients with a g551d mutation and treated with ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
4 |
Deuterated ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
5 |
Elexacaftor-tezacaftor-ivacaftor exposure |
Elexacaftor |
[3] D09916 D09916, D11041 D11041, D11507 D11507 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
6 |
Ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
7 |
Ivacaftor (proposed inn) |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
8 |
Ivacaftor 125mg tablet |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
9 |
Ivacaftor 150 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
10 |
Ivacaftor 150 mg or 250 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
11 |
Ivacaftor 25 mg/75 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
12 |
Ivacaftor 75 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
13 |
Ivacaftor 75 mg/150 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
14 |
Ivacaftor exposed |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
15 |
Ivacaftor or elexacaftor/tezacaftor/ivacaftor |
Elexacaftor |
[3] D09916 D09916, D11041 D11041, D11507 D11507 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
16 |
Ivacaftor+lumacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
17 |
Ivacaftor/ataluren |
Ataluren |
[2] D09323 D09323, D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
18 |
Ivacaftor/kalydeco |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
19 |
Lumacaftor / ivacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
20 |
Lumacaftor plus ivacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
21 |
Lumacaftor plus ivacaftor combination |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
22 |
Lumacaftor, ivacaftor drug combination |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
23 |
Lumacaftor-ivacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
24 |
Lumacaftor-ivacaftor treatment |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
25 |
Lumacaftor/ivacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
26 |
Lumacaftor/ivacaftor 100mg/125mg tablets |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
27 |
Lumacaftor/ivacaftor 200mg/125mg |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
28 |
Lumacaftor/ivacaftor 200mg/125mg tablets |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
29 |
Lumacaftor/ivacaftor 200mg/83mg tablet |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
30 |
Orkambi: contains lumacaftor and ivacaftor |
Ivacaftor |
[2] D09916 D09916, D10134 D10134 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
31 |
Tezacaftor/ivacaftor |
Ivacaftor |
[2] D09916 D09916, D11041 D11041 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
32 |
Tezacaftor/ivacaftor + ivacaftor |
Ivacaftor |
[2] D09916 D09916, D11041 D11041 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
33 |
Tezacaftor/ivacaftor 100mg/150mg |
Ivacaftor |
[2] D09916 D09916, D11041 D11041 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
34 |
Tezacaftor/ivacaftor/100mg/150mg |
Ivacaftor |
[2] D09916 D09916, D11041 D11041 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
35 |
Vx-659/tezacaftor/ivacaftor |
Ivacaftor |
[2] D09916 D09916, D11041 D11041 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
36 |
Vx-661 plus ivacaftor combination |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
37 |
Vx-661/ivacaftor |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
38 |
Vx-661/ivacaftor (vx-770) 100mg/150 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
39 |
Vx-661/ivacaftor 100 mg/ 150 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
40 |
Vx-661/ivacaftor 100mg/150 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
41 |
Vx-661/ivacaftor 100mg/150mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |
42 |
Vx-661/ivacaftor 50 mg/ 75 mg |
Ivacaftor |
[1] D09916 D09916 💬 |
CFTR [1] CFTR 💬 |
ABC transporters [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway |
299 [1] 299 💬 |