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e.g. Sirolimus, Adalimumab

ABCDEFGH I JKLMNOPQRSTUVWXYZother

46 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  150-mg ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 2  150mg ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 3  Cf patients with a g551d mutation and treated with ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 4  Deuterated ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 5  Elexacaftor-tezacaftor-ivacaftor exposure  Elexacaftor  [3] D09916, D11041, D11507 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 6  Ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 7  Ivacaftor (proposed inn)  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 8  Ivacaftor 125mg tablet  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 9  Ivacaftor 150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 10  Ivacaftor 150 mg or 250 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 11  Ivacaftor 25 mg/75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 12  Ivacaftor 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 13  Ivacaftor 75 mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 14  Ivacaftor exposed  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 15  Ivacaftor or elexacaftor/tezacaftor/ivacaftor  Elexacaftor  [3] D09916, D11041, D11507 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 16  Ivacaftor+lumacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 17  Ivacaftor/ataluren  Ataluren  [2] D09323, D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 18  Ivacaftor/kalydeco  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 19  Kalydeco  -  -  -  -  [1] 299 💬 
 20  Kalydeco 150 mg film-c  -  -  -  -  [1] 299 💬 
 21  Kalydeco 150 mg film-coated tablets  -  -  -  -  [1] 299 💬 
 22  Kalydeco 150mg  -  -  -  -  [1] 299 💬 
 23  Lumacaftor / ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 24  Lumacaftor plus ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 25  Lumacaftor plus ivacaftor combination  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 26  Lumacaftor, ivacaftor drug combination  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 27  Lumacaftor-ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 28  Lumacaftor-ivacaftor treatment  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 29  Lumacaftor/ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 30  Lumacaftor/ivacaftor 100mg/125mg tablets  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 31  Lumacaftor/ivacaftor 200mg/125mg  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 32  Lumacaftor/ivacaftor 200mg/125mg tablets  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 33  Lumacaftor/ivacaftor 200mg/83mg tablet  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 34  Orkambi: contains lumacaftor and ivacaftor  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 35  Tezacaftor/ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 36  Tezacaftor/ivacaftor + ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 37  Tezacaftor/ivacaftor 100mg/150mg  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 38  Tezacaftor/ivacaftor/100mg/150mg  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 39  Vx-659/tezacaftor/ivacaftor  Ivacaftor  [2] D09916, D11041 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 40  Vx-661 plus ivacaftor combination  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 41  Vx-661/ivacaftor  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 42  Vx-661/ivacaftor (vx-770) 100mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 43  Vx-661/ivacaftor 100 mg/ 150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 44  Vx-661/ivacaftor 100mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 45  Vx-661/ivacaftor 100mg/150mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 46  Vx-661/ivacaftor 50 mg/ 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 

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