1 |
Methotrexate(mtx) |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
046 [1] 46 💬 |
2 |
Methotrexate(mtx) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
046 [1] 46 💬 |
3 |
Methotrexate(mtx) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol. |
Methotrexate |
[2] D00142 D00142, D02115 D02115 💬 |
DHFR [2] DHFR, DHFR2 💬 |
Antifolate resistance [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
046 [1] 46 💬 |
4 |
Tocilizumab + methotrexate(mtx) |
Methotrexate |
[3] D00142 D00142, D02115 D02115, D02596 D02596 💬 |
DHFR [3] DHFR, DHFR2, IL6R 💬 |
Antifolate resistance [17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [1] 46 💬 |
5 |
Tocilizumab+methotrexate(mtx) |
Methotrexate |
[3] D00142 D00142, D02115 D02115, D02596 D02596 💬 |
DHFR [3] DHFR, DHFR2, IL6R 💬 |
Antifolate resistance [17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor |
046 [1] 46 💬 |