Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Administration of rituximab and methylprednisolone	Methylprednisolone	[7] D00407, D00751, D00979, D02994, D05000, D05001, D05002 💬	[2] MS4A1, NR3C1 💬	[2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction	[1] 51 💬
2	Corticosteroid treatment (methylprednisolone or prednisolone)	Methylprednisolone	[14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 64 💬
3	Cyclophosphamide, azathioprine,prednisone,methylprednisolone	Azathioprine	[11] D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 42, 43, 45 💬
4	Infliximab, methylprednisolone, methotrexate	Infliximab	[9] D00142, D00407, D00751, D00979, D02115, D02598, D05000, D05001, D05002 💬	[4] DHFR, DHFR2, NR3C1, TNF 💬	[70] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 46 💬
5	Interferon-beta-1a (avonex) plus methylprednisolone	Human interferon beta	[7] D00407, D00751, D00979, D04554, D05000, D05001, D05002 💬	[3] IFNAR1, IFNAR2, NR3C1 💬	[19] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[1] 13 💬
6	Intravenous (i.v.) methylprednisolone 1000 mg, total 9	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 222 💬
7	Intravenous methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[2] 13, 145 💬
8	Iv methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
9	Iv methylprednisolone (steroids)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
10	Megadose oral methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
11	Methotrexate + methylprednisolone	Methotrexate	[8] D00142, D00407, D00751, D00979, D02115, D05000, D05001, D05002 💬	[3] DHFR, DHFR2, NR3C1 💬	[6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate	[1] 46 💬
12	Methylprednisolon	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[4] 13, 14, 51, 66 💬
13	Methylprednisolon (solu-medrol)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 14 💬
14	Methylprednisolon-21-hydrogensuccinat, natriumsalz	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
15	Methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
16	Methylprednisolone (drug)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
17	Methylprednisolone (mp)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[2] 60, 285 💬
18	Methylprednisolone (mp) or prednisone (pred)	Methylprednisolone	[7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 66 💬
19	Methylprednisolone (or other glucocorticoid)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
20	Methylprednisolone (solu-medrol)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 14 💬
21	Methylprednisolone 1250 mg/24h x3 days	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
22	Methylprednisolone acetate	Acetate	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 51 💬
23	Methylprednisolone bolus iv 15 mg/kg/d for 3 days.	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 84 💬
24	Methylprednisolone hemisuccinate	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
25	Methylprednisolone iv	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
26	Methylprednisolone mylan générique	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 66 💬
27	Methylprednisolone or budesonide	Budesonide	[7] D00246, D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 96 💬
28	Methylprednisolone or prednisolone	Methylprednisolone	[14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 65 💬
29	Methylprednisolone po	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
30	Methylprednisolone pulse	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[2] 66, 220 💬
31	Methylprednisolone sodium hemisuccinate	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[2] 13, 97 💬
32	Methylprednisolone sodium succinate	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[6] 13, 46, 49, 50, 51, 211 💬
33	Methylprednisolone(intravenously in the 1st-2nd-3rd month )	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 66 💬
34	Methylprednisolone(intravenously in the 1st-3rd-5th month)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 66 💬
35	Methylprednisoloni natrii succinas	-	-	-	-	[1] 50 💬
36	Oral 5-asa+/-topical 5-asa+iv corticosteroids / po methylprednisolone	Mesalazine	[7] D00377, D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 97 💬
37	Oral methylprednisolone 625 mg/24h x3 days	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 13 💬
38	Prednisone (and methylprednisolone)	Methylprednisolone	[7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
39	Prednisone, methylprednisolone,cyclophosphamides	Methylprednisolone	[7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 42, 43, 45 💬

Back to top