Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Azathioprine or mycophenolate mofetil	Azathioprine	[6] D00238, D00752, D03033, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 162 💬
2	Cellcept (mycophenolate mofetil)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[2] 42, 43 💬
3	Cyclosporine combine with mycophenolate mofetil	Cyclosporine	[5] D00184, D00752, D05094, D05095, D05096 💬	[7] IMPDH1, IMPDH2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[35] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[1] 283 💬
4	Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)	Azathioprine	[8] D00142, D00238, D00752, D02115, D03033, D05094, D05095, D05096 💬	[4] DHFR, DHFR2, IMPDH1, IMPDH2 💬	[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism	[1] 49 💬
5	Mycophenolate mofetil	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
6	Mycophenolate mofetil (cellcept)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[2] 11, 13 💬
7	Mycophenolate mofetil (mmf)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[7] 13, 49, 51, 60, 65, 66, 222 💬
8	Mycophenolate mofetil (mmf) 3 g/day	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 35 💬
9	Mycophenolate mofetil 2 g/day	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 35 💬
10	Mycophenolate mofetil [cellcept]	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 11 💬
11	Mycophenolate mofetil orally 1000 mg twice a day (bid)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 222 💬
12	Mycophenolate mofetil plus lower dose of prednisone	Mycophenolate mofetil	[5] D00473, D00752, D05094, D05095, D05096 💬	[3] IMPDH1, IMPDH2, NR3C1 💬	[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism	[1] 66 💬
13	Mycophenolate mofetil(mmf)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 224 💬
14	Mycophenolate mofetil, low dose steroid	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 222 💬
15	Mycophenolate mofetil,methotrexate	Methotrexate	[6] D00142, D00752, D02115, D05094, D05095, D05096 💬	[4] DHFR, DHFR2, IMPDH1, IMPDH2 💬	[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism	[3] 42, 43, 45 💬
16	Mycophenolic acid	Mycophenolic acid	[1] D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[8] 11, 43, 49, 51, 60, 66, 96, 222 💬
17	Mycophenolic acid mofetil	Mycophenolic acid	[1] D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 60 💬
18	Prednisolone and mycophenolate mofetil	Mycophenolate mofetil	[12] D00472, D00752, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05094, D05095, D05096 💬	[3] IMPDH1, IMPDH2, NR3C1 💬	[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism	[1] 222 💬
19	Prednisone and mycophenolate mofetil	Mycophenolate mofetil	[5] D00473, D00752, D05094, D05095, D05096 💬	[3] IMPDH1, IMPDH2, NR3C1 💬	[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism	[1] 300 💬
20	Prednisone, ciclosporin and mycophenolate mofetil	Cyclosporine	[6] D00184, D00473, D00752, D05094, D05095, D05096 💬	[8] IMPDH1, IMPDH2, NR3C1, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[36] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Neuroactive ligand-receptor interaction, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[1] 222 💬
21	Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil)	Azathioprine	[8] D00107, D00238, D00752, D03033, D05094, D05095, D05096, D08556 💬	[7] IMPDH1, IMPDH2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[35] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[1] 11 💬

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