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32 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  20 mg sildenafil citrate by mouth  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 2  5% sildenafil cream  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 50 💬 
 3  Access program - sildenafil citrate, viagra, revatio  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 4  Bosentan and sildenafil  Bosentan  [4] D01227, D02229, D07538, D08514 💬  [3] EDNRA, EDNRB, PDE5A 💬  [11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 5  Duo-therapy with sildenafil + bosentan  Bosentan  [4] D01227, D02229, D07538, D08514 💬  [3] EDNRA, EDNRB, PDE5A 💬  [11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 6  Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan)  Bosentan  [6] D01227, D02008, D02229, D07538, D08514, D10135 💬  [3] EDNRA, EDNRB, PDE5A 💬  [11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 7  G04be03- sildenafil - sildenafil (citrato)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 8  Mono-therapy with sildenafil  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 9  Oral sildenafil  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 10  Other: standard of care sildenafil  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [2] 90, 301 💬 
 11  Sildenafil  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 
 12  Sildenafil (50 mg)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 85 💬 
 13  Sildenafil (acute-1 hour)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 299 💬 
 14  Sildenafil (as citrate)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 15  Sildenafil (revatio)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 16  Sildenafil (revatio) 20 mg tid  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 17  Sildenafil (subchronic-4 weeks)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 299 💬 
 18  Sildenafil 20 mg tablets  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 278 💬 
 19  Sildenafil 20mg  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [2] 51, 86 💬 
 20  Sildenafil 20mg and bosentan 62.5mg  Bosentan  [4] D01227, D02229, D07538, D08514 💬  [3] EDNRA, EDNRB, PDE5A 💬  [11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 51, 86 💬 
 21  Sildenafil 40mg oral capsule  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 299 💬 
 22  Sildenafil and losartan  Losartan  [4] D00357, D02229, D08146, D08514 💬  [2] AGTR1, PDE5A 💬  [18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 85 💬 
 23  Sildenafil by injection  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 210 💬 
 24  Sildenafil citrate  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [4] 51, 85, 86, 225 💬 
 25  Sildenafil citrate (uk-92,480)  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 26  Sildenafil filmtabletten  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 27  Sildenafil singly or in association with bosentan  Bosentan  [4] D01227, D02229, D07538, D08514 💬  [3] EDNRA, EDNRB, PDE5A 💬  [11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 28  Sildenafil therapy  Sildenafil  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 51 💬 
 29  Sitaxsentan and sildenafil  Sildenafil  [3] D02229, D07171, D08514 💬  [2] EDNRA, PDE5A 💬  [9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 30  Sodium tanshinone iia sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth  Dextrose, unspecified form  [2] D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 86 💬 
 31  Tadalafil and sildenafil  Sildenafil  [3] D02008, D02229, D08514 💬  [1] PDE5A 💬  [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [1] 113 💬 
 32  Viagra  -  -  -  -  [3] 86, 96, 225 💬 

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