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16 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Acetaminophen [9] Acetaminophen; Acetaminophen tab 650mg; Acetaminophen tablets; Acetaminophen/paracetamol; Multi-modal pain management [acetaminophen + gabapentin]; Oxycodone/acetaminophen; Paracetamol (acetaminophen); Tramadol /acetaminophen; Tramadol hydrochloride + acetaminophen;  [1] D00217 💬 [2] PTGS1, PTGS2 💬 [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [16]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
 2  Acetylsalicylic acid [2] Acetylsalicylic acid; Acetylsalicylic acid at 1st visit,;  [1] D00109 💬 [2] PTGS1, PTGS2 💬 [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
 3  Alpha-1-proteinase inhibitor -  -  [3] 231, 298, 299 💬
 4  Alvelestat [5] Alvelestat; Alvelestat (mph966); Alvelestat oral tablet - dose 1; Alvelestat oral tablet - dose 2; Alvelestat tosylate;  -  -  [1] 231 💬
 5  Carbamazepine [2] Carbamazepine; Drug-carbamazepine (tegretol xr);  [1] D00252 💬 [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [2] 13, 231 💬
 6  Fentanyl [8] Fentanyl; Fentanyl (high dose); Fentanyl (low dose); Fentanyl (low dose) + dexmedetomidine; Fentanyl transdermal patch; Multi-modal pain management [fentanyl]; Standard analgesia use [fentanyl]; Transdermal fentanyl matrix, gabapentin;  [2] D00320
D01399 💬
[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [4] 46, 70, 215, 231 💬
 7  Hyaluronic acid [5] Hyaluronic acid; Hyaluronic acid and chondroitin sulfate; Hyaluronic acid inhalation solution; Hyaluronic acid/chondroitin sulfate; Standard care hyaluronic acid eye drops;  [1] D08043 💬  -  [7] 46, 53, 70, 97, 226, 231, 299 💬
 8  Interleukin-1 alpha, human recombinant -  -  [11] 46, 65, 84, 85, 96, 97, 140, 161, 231, 271, 299 💬
 9  Lidocaine [11] 5% lidocaine/5 mg/ml 0.02% estradiol compound cream; Alkalinized lidocaine-heparin; Bladder instillation with heparin/ lidocaine; Heparin & alkalinized lidocaine bladder instillation; Lidocaine; Lidocaine 1% injectable solution; Lidocaine 2% without vessel constrictor; Lidocaine injection 2%; Lidocaine patch 5%; Lidocaine releasing intravesical system - liris®; Local anesthesia (lidocaine hydrochloride);  [3] D00358
D02086
D08127 💬
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
 10  Lorazepam [1] Lorazepam;  [1] D00365 💬 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [1] 231 💬
 11  Midazolam [7] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Midazolam; Midazolam 2 mg; Midazolam 3 mg; Midazolam injection; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142; S-ketamine & midazolam;  [3] D00550
D00696
D05028 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬
 12  Ondansetron [3] Ondansetron; Ondansetron 8 mg film-coated tablets; Ondansetron hydrochloride dihydrate;  [2] D00456
D00678 💬
[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 [2] Serotonergic synapse, Taste transduction  [3]  6 , 97, 231 💬
 13  Oxycodone [17] Extended-release oxycodone; Oxycodone; Oxycodone by patient-controlled analgesia (pca); Oxycodone depot ”sandoz”, depot tablets; Oxycodone hydrochloride; Oxycodone naloxone prolonged release tablets; Oxycodone orion; Oxycodone/acetaminophen; Oxycodone/naloxone prolonged release t; Oxycodone/naloxone prolonged release tablets; Oxycodone/naloxone prolonged release tablets 10 mg /5 mg; Oxycodone/naloxone prolonged release tablets 10/5 mg; Oxycodone/naloxone prolonged release tablets 20 mg /10 mg; Oxycodone/naloxone prolonged release tablets 20/10 mg; Oxycodone/naloxone prolonged release tablets 5 mg /2.5 mg; Oxycodone/naloxone prolonged release tablets 5/2.5 mg; Pr oxycodone;  [3] D03783
D05312
D05462 💬
[3] OPRD1, OPRK1, OPRM1 💬 [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [7]  6 , 13, 46, 70, 226, 231, 298 💬
 14  Phenylbutyric acid [1] D05868 💬  -  [12]  2 ,  3 ,  6 ,  8 , 15, 93, 94, 231, 244, 251, 297, 299 💬
 15  Salbutamol [9] Nebulized combination ipratropium bromide with salbutamol; Other: salbutamol nebulisation and with cpap; R-salbutamol; R-salbutamol sulphate; Salbutamol; Salbutamol 4mg tablet; Salbutamol sulfate; Salbutamol sulfate ph. eur.; Salbutamol wzf 4 mg;  [1] D02147 💬 [1] ADRB2 💬 [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
 16  Tretinoin [3] Pioglitazone and tretinoin; Tretinoin; Tretinoin and pioglitazone hcl;  [1] D00094 💬 [3] PML, RARA, RARB 💬 [12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis  [5]  2 , 63, 75, 94, 231 💬