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12 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Allopurinol [4] Allopurinol; Allopurinol sandoz 100 mg, tabletten; Allopurinol sodium; Azathioprine and allopurinol;  [1] D00224 💬 [1] XDH 💬 [5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism  [6]  6 , 46, 57, 66, 96, 97 💬
 2  Benazepril [4] Benazepril; Benazepril hydrochloride tablets; Benazepril pill; Benazepril, valsartan and fluvastatin;  [2] D00620
D07499 💬
[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system  [4] 49, 57, 218, 224 💬
 3  Carvedilol [2] Carvedilol; Spironolactone captopril carvedilol;  [2] D00255
D03415 💬
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 [12] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [5]  6 , 57, 86, 113, 210 💬
 4  Dobutamine [2] Dobutamine; Other: dobutamine;  [4] D00632
D03879
D03880
D03881 💬
[1] ADRB1 💬 [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [3] 57, 58, 215 💬
 5  Doxazosin [2] Doxazosin; Metoprolol succinate + doxazosin;  [2] D00608
D07874 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [2] 57, 67 💬
 6  Filgrastim [7] Ep2006 (filgrastim); Filgrastim; Filgrastim (g-csf); Filgrastim hexal; Filgrastim, alemtuzumab; Granulocyte colony-stimulating factor (filgrastim); Pegfilgrastim;  [1] D03235 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
 7  Honey [3] Device: manuka honey sinus rinse; Honey; Other: honey;  [1] D06776 💬  -  [3] 57, 98, 299 💬
 8  Lenograstim [3] Granocyte - 34 million iu (lenograstim rhug-csf); Granocyte lenograstim; Lenograstim;  [1] D03247 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [7]  2 , 13, 16, 18, 19, 57, 65 💬
 9  Metoprolol [8] Metoprolol; Metoprolol succinate; Metoprolol succinate + doxazosin; Metoprolol tartrate 50 mg; Metoprolol tartrate oral tablet; Metoprololsuccinat orion 25mg; Metoprololsuccinat ”orion” 25mg; Tesofensine/metoprolol;  [3] D00601
D02358
D05011 💬
[1] ADRB1 💬 [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [6] 17, 57, 58, 113, 193, 226 💬
 10  Ubidecarenone [1] D01065 💬  -  [13]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 86, 113, 193, 214, 215 💬
 11  Valsartan [5] Benazepril, valsartan and fluvastatin; Enalapril valsartan methylprednisone; Sacubitril valsartan; Sacubitril/valsartan; Valsartan;  [1] D00400 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [7] 57, 58, 66, 75, 218, 222, 224 💬
 12  Water [31] 15 o water; 15-o labeled water; 5% glucose water solution; Behavioral: diet and water adjustment; Behavioral: water tracking; Cholecalciferol concentrate (water-dispersible form); Device: manual toothbrush and water flosser (philips sonicare airfloss); Device: sonic toothbrush (philips sonicare) and water flosser (philips sonicare airfloss); Dextrose, 5% in water; High water intake; Lactose in water; Other: ad libitum water intake; Other: dead sea solar and water treatment; Other: dextrose water 5%; Other: exercise followed cold water immersion; Other: harkány medicinal water; Other: high water intake; Other: potable water; Other: water; Other: water prescription; Pl 12185/0002 & pl 12185/0005(water for injection); Procedure: water exercises; Pseudoephedrine + 480 ml water; Pseudoephedrine + 50 ml water; Sterile water; Sterile water for injection; Sterilised water for injections; Water; Water for injection; Water for injections; Water for injections, ep;  [1] D00001 💬  -  [22]  2 ,  5 ,  6 , 13, 17, 19, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299 💬