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e.g. Sirolimus, Adalimumab

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54 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Acetaminophen [9] Acetaminophen; Acetaminophen tab 650mg; Acetaminophen tablets; Acetaminophen/paracetamol; Multi-modal pain management [acetaminophen + gabapentin]; Oxycodone/acetaminophen; Paracetamol (acetaminophen); Tramadol /acetaminophen; Tramadol hydrochloride + acetaminophen;  [1] D00217 💬 [2] PTGS1, PTGS2 💬 [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [16]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
 2  Acetate [98] 11c-acetate; 2-(2-(2-amino-9h-purin-9-yl)ethyl)-1,3-propanediol diacetate ester; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; 90 mg hydrocortisone acetate suppository with sephure suppository applicator; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Device: cellulose acetate with petrolatum; Dichloroacetate; Dichloroacetate sodium; Dirucotide acetate; Edratide acetate; Etiprednol dicloacetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (gtr); Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate [ga]; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; L-lysyl-d-prolyl-lthreonine acetate, lyophilisate; Lanreotide acetate; Lapaquistat acetate and current lipid-lowering treatment; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Methylprednisolone acetate; Nomegestrol acetate; Octreotide acetate; Oxaloacetate (oaa); Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Plovamer acetate 0.5 milligram (mg); Plovamer acetate 10 mg; Plovamer acetate 20 mg; Plovamer acetate 3 mg; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Procedure: warm compress prior to injection of glatiramer acetate; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]- phenyl]-acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tetracosactide hexaacetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate;  -  -  -  [43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
 3  Alprostadil [1] Alprostadil;  [2] D00180
D02705 💬		 [1] PTGER1 💬 [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer  [2] 51, 70 💬
 4  Amino acids [2] Amino acids; Free amino acids intake;  -  -  -  [3] 70, 240, 298 💬
 5  Aminocaproic acid [2] Aminocaproic acid; Epsilon-aminocaproic acid (eaca);  [1] D00160 💬 [1] PLG 💬 [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [1] 70 💬
 6  Apple [2] Apple; Device: apple watch and app;  -  -  -  [1] 70 💬
 7  Botulinum toxin type A [6] Botulinum toxin type a; Botulinum toxin type a (nabota®) injection into the gastrocnemius muscle; Botulinum toxin type a 200u; Botulinum toxin type a 300u; Botulinum toxin type a infiltrations; Clostridium botulinum toxin type a;  [1] D00783 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle  [13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
 8  Bupivacaine [10] Bupivacaine; Bupivacaine hydrochloride; Bupivacaine hydrochloride 0.5% (marcaine, pfizer); Bupivacaine injection 0.5%; Bupivacaine/epinephrine/dexamethasone; Ercp with bupivacaine infusion; Lap tap bupivacaine/epinephrine; Levobupivacaine; Liposomal bupivacaine; Us tap bupivacaine/epinephrine;  [2] D01450
D07552 💬		 [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
 9  Buprenorphine [2] Buprenorphine; Buprenorphine transdermal patch;  [2] D00836
D07132 💬		 [2] OPRK1, OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2] 46, 70 💬
 10  Carbon monoxide [3] Carbon monoxide; Inhaled carbon monoxide; Other: carbon monoxide-bubbled mediums;  [1] D09706 💬  -  -  [7]  6 , 13, 53, 70, 85, 86, 298 💬
 11  Celecoxib [8] Celebra (celecoxib); Celecoxib; Celecoxib (celebrex); Celecoxib 200 milligrams; Celecoxib 200mg capsule; Celecoxib 400 milligrams; Celecoxib, celebrex®; Fixed dose combination ciprofloxacin/celecoxib;  [1] D00567 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [9]  2 ,  3 , 34, 46, 70, 89, 161, 171, 271 💬
 12  Cilostazol [1] Cilostazol;  [1] D01896 💬 [3] PDE3A, PDE3B, TBXA2R 💬 [14] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 51, 70 💬
 13  Creatinine [1] Creatinine;  [1] D03600 💬  -  -  [4]  2 , 46, 60, 70 💬
 14  Dexamethasone [48] Bortezomib/dexamethasone; Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Bupivacaine/epinephrine/dexamethasone; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Control intervention (no dexamethasone); Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cyclophosphamide, bortezomib, and dexamethasone (cybord); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Device: dexamethasone injection; Dexamethasone; Dexamethasone (1 cycle); Dexamethasone (4 cycles); Dexamethasone (50mg 1dd6, 3 consecutive days/month); Dexamethasone 0,1 mg tablets; Dexamethasone 0,5mg; Dexamethasone 0.5mg tablet; Dexamethasone 0.5mg/5ml solution; Dexamethasone 0.5mg/5ml solution in mucolox™; Dexamethasone 1,5 mg tablets; Dexamethasone 21-dihydrogen phosphate; Dexamethasone 21-phosphate; Dexamethasone 2mg tablets; Dexamethasone 4 mg jenapharm; Dexamethasone abcur; Dexamethasone and rituximab; Dexamethasone oral tablet 8mg (dexamethasone krka tablets(8mg), warsaw, poland).; Dexamethasone parotid irrigation; Dexamethasone sodium phosphate; Dexamethasone sodium phosphate 250 mg/ 10 ml; Dexamethasone sodium phosphate 250 mg/10 ml solution; Dexamethasone sodium phosphate ph. eur.; Dexamethasone sodium sulfate; Dexamethasone soduim phosphate; Dexamethasone, 40 mg; Diagnostic test: dexamethasone test; High dose dexamethasone pulses; Intraarticular dexamethasone; Intravenous dexamethasone 1 mg; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Lenalidomide, dexamethasone and cyclophosphamide; Melphalan, thalidomide and dexamethasone; Mmf and dexamethasone; Peri-neural dexamethasone 1 mg; Pomalidomide and dexamethasone; Procedure: epidural steroid (dexamethasone) injection;  [9] D00292
D00975
D01510
D01615
D01632
D01948
D02174
D02591
D02592 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
 15  Dexmedetomidine [10] Dexmedetomidine; Dexmedetomidine 1; Dexmedetomidine 2; Dexmedetomidine 3; Dexmedetomidine group; Dexmedetomidine hydrochloride; Dexmedetomidine hydrochloride infusion; Dexmedetomidine with ropivacaine; Fentanyl (low dose) + dexmedetomidine; Scopolamine, atropine, edaravone and dexmedetomidine;  [2] D00514
D01205 💬		 [3] ADRA2A, ADRA2B, ADRA2C 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
 16  Dextrose, unspecified form - -  -  -  [18]  2 ,  6 , 13, 49, 50, 56, 60, 65, 70, 75, 86, 88, 96, 160, 195, 254, 257, 299 💬
 17  Diphenhydramine [2] Diphenhydramine; Diphenhydramine hydrochloride;  [6] D00300
D00669
D02419
D03285
D03360
D03854 💬		 [1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction  [8] 11, 49, 51, 70, 86, 96, 222, 256 💬
 18  Erythropoietin [4] Erythropoietin; Erythropoietin human recombinant (eporh); Recombinant human erythropoietin; Recombinant human erythropoietin(rhepo);  [1] D03231 💬 [1] EPOR 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [10]  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
 19  Esketamine [2] Esketamine; Esketamine hydrochloride;  [1] D07283 💬 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [3]  2 ,  4 , 70 💬
 20  Fentanyl [8] Fentanyl; Fentanyl (high dose); Fentanyl (low dose); Fentanyl (low dose) + dexmedetomidine; Fentanyl transdermal patch; Multi-modal pain management [fentanyl]; Standard analgesia use [fentanyl]; Transdermal fentanyl matrix, gabapentin;  [2] D00320
D01399 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [4] 46, 70, 215, 231 💬
 21  Gabapentin [9] Gabapentin; Gabapentin prescriptions; Gabapentina; Gabapentina kern pharma; Gabapentine; Gabapentine 300mg; Multi-modal pain management [acetaminophen + gabapentin]; Multi-modal pain management [valium + gabapentin]; Transdermal fentanyl matrix, gabapentin;  [1] D00332 💬 [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬 [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [5]  6 , 13, 19, 70, 298 💬
 22  Heparin [9] Alkalinized lidocaine-heparin; Bladder instillation with heparin/ lidocaine; Device: heparin-induced extracorporeal ldl precipitation; Heparin; Heparin & alkalinized lidocaine bladder instillation; Heparin 25mg inhalation powder, hard capsule; Heparin sodium; Intralipid/heparin; Low molecular weight heparin calcium injection;  [1] D07510 💬 [1] SERPINC1 💬 [1] Complement and coagulation cascades  [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
 23  Hyaluronic acid [5] Hyaluronic acid; Hyaluronic acid and chondroitin sulfate; Hyaluronic acid inhalation solution; Hyaluronic acid/chondroitin sulfate; Standard care hyaluronic acid eye drops;  [1] D08043 💬  -  -  [7] 46, 53, 70, 97, 226, 231, 299 💬
 24  Hydromorphone [2] Hydromorphone; Standard analgesia use [hydromorphone];  [2] D00839
D08047 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬
 25  Ketamine [6] Esketamine; Esketamine hydrochloride; Ketamine; Multi-modal pain management [intravenous ketamine]; S-ketamine; S-ketamine & midazolam;  [2] D00711
D08098 💬		 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
 26  Ketorolac [2] Ketorolac; Ketorolac tromethamine;  [2] D00813
D08104 💬		 [2] PTGS1, PTGS2 💬 [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [2] 70, 226 💬
 27  Lidocaine [11] 5% lidocaine/5 mg/ml 0.02% estradiol compound cream; Alkalinized lidocaine-heparin; Bladder instillation with heparin/ lidocaine; Heparin & alkalinized lidocaine bladder instillation; Lidocaine; Lidocaine 1% injectable solution; Lidocaine 2% without vessel constrictor; Lidocaine injection 2%; Lidocaine patch 5%; Lidocaine releasing intravesical system - liris®; Local anesthesia (lidocaine hydrochloride);  [3] D00358
D02086
D08127 💬		 [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [12]  6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
 28  Limaprost [1] Limaprost;  [1] D02722 💬 [1] PTGER1 💬 [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer  [1] 70 💬
 29  Magnesium [19] (s)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide; (s)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide; Magnesium; Magnesium aspartate; Magnesium aspartate hydrochloride; Magnesium citrate; Magnesium gluconate; Magnesium hydroxide; Magnesium oxide; Magnesium sulfate; Magnesium with ropivacaine; Mineral boost (magnesium); Nexium (esomeprazole magnesium); Omeprazole magnesium; Saroglitazar magnesium 2 mg; Saroglitazar magnesium 4 mg; Sodium picosulfate, magnesium oxide and citric acid; Sodium picosulfate/magnesium citrate laxative; Sulfate, magnesium;  -  -  -  [17]  6 , 11, 13, 46, 51, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬
 30  Methamidophos - -  -  -  [18]  2 , 11, 13, 19, 46, 49, 58, 65, 70, 85, 86, 98, 113, 118, 129, 298, 299, 300 💬
 31  Midazolam [7] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Midazolam; Midazolam 2 mg; Midazolam 3 mg; Midazolam injection; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142; S-ketamine & midazolam;  [3] D00550
D00696
D05028 💬		 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬
 32  Mirogabalin [1] Mirogabalin;  [1] D11203 💬 [2] CACNA2D1, CACNA2D2 💬 [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [1] 70 💬
 33  Misoprostol [1] Misoprostol;  [1] D00419 💬 [3] PTGER2, PTGER3, PTGER4 💬 [9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway  [3] 46, 70, 271 💬
 34  Morphine [7] Intraarticular morphine; Morphine; Morphine hexal; Morphine hydrochloride; Morphine pca; Morphine sulfate; Morphine sulphate in intrasite gel;  [3] D00842
D02271
D08233 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [5] 36, 46, 70, 85, 86 💬
 35  Nicardipine [1] Nicardipine;  [2] D00617
D08270 💬		 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 [36] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 70, 86 💬
 36  Oxycodone [17] Extended-release oxycodone; Oxycodone; Oxycodone by patient-controlled analgesia (pca); Oxycodone depot ”sandoz”, depot tablets; Oxycodone hydrochloride; Oxycodone naloxone prolonged release tablets; Oxycodone orion; Oxycodone/acetaminophen; Oxycodone/naloxone prolonged release t; Oxycodone/naloxone prolonged release tablets; Oxycodone/naloxone prolonged release tablets 10 mg /5 mg; Oxycodone/naloxone prolonged release tablets 10/5 mg; Oxycodone/naloxone prolonged release tablets 20 mg /10 mg; Oxycodone/naloxone prolonged release tablets 20/10 mg; Oxycodone/naloxone prolonged release tablets 5 mg /2.5 mg; Oxycodone/naloxone prolonged release tablets 5/2.5 mg; Pr oxycodone;  [3] D03783
D05312
D05462 💬		 [3] OPRD1, OPRK1, OPRM1 💬 [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [7]  6 , 13, 46, 70, 226, 231, 298 💬
 37  Oxygen [39] Behavioral: respiratory and exercise therapy with supplemental oxygen; Combination product: hyperbaric oxygen therapy-; Continuous oxygen; Device: auto-titrating oxygen system; Device: capacity of muscular oxygen extraction; Device: high flow nasal oxygen cannula; Device: hyperbaric oxygen; Device: intermittent exposure to oxygen via oro-nasal mask; Device: nocturnal oxygen , nocturnal bi-level positive pressure ventilation; Device: oxygen; Device: oxygen saturation; Device: standard oxygen therapy/ra; Diagnostic test: maximum oxygen uptake; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Other: 60% oxygen; Other: air - oxygen; Other: hyperbaric oxygen; Other: hyperbaric oxygen therapy; Other: muscle oxygenation; Other: optional blood-oxygen-level dependent functionalmri; Other: oxygen; Other: oxygen (2liter/min); Other: oxygen (4liter/min); Other: oxygen - air; Other: oxygen supplementation; Oxygen; Oxygen 40 %; Oxygen supplementation; Oxygen, liquid; Perfluorinated gas/oxygen mixture; Procedure: hyperbaric oxygen; Procedure: hyperbaric oxygen therapy; Procedure: long term oxygen therapy; Procedure: oxygen flow at the optic nerve head measurement; Procedure: supplemental oxygen via a mask; Standard analgesia use [oxygen];  [1] D00003 💬  -  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬
 38  Oxymorphone - [1] D08323 💬 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬
 39  Parathyroid hormone [12] Enterabio's oral parathyroid hormone (1-34); Human recombinant parathyroid hormone; Immediate post operative bioassay of parathyroid hormone; Inn parathyroid hormone (1-84) human; Parathyroid hormone; Parathyroid hormone (1-84) human recombinant; Parathyroid hormone (rdna); Rcombinant human parathyroid hormone [rhpth(1-84)]; Recombinant human parathyroid hormone (1-84); Recombinant human parathyroid hormone [rhpth(1-84)]; Synthetic human parathyroid hormone 1-34; Teriparatide [rdna origin] contains recombinant human parathyroid hormone (1-34);  [1] D05364 💬 [2] PTH1R, PTH2R 💬 [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [4] 65, 70, 235, 326 💬
 40  Phosphate ion - -  -  -  [30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
 41  Pidolic acid - -  -  -  [2] 46, 70 💬
 42  Pregabalin [3] Antioxidant plus pregabalin; Pregabalin; Pregabalin 75mg;  [1] D02716 💬 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [5] 13, 36, 46, 70, 298 💬
 43  Remifentanil [1] Remifentanil;  [2] D01177
D08473 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2]  6 , 70 💬
 44  Ropivacaine [5] Dexmedetomidine with ropivacaine; Magnesium with ropivacaine; Ropivacaine; Ropivacaine plus normal saline; Tramadol with ropivacaine;  [2] D04048
D08490 💬		 [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3] 36, 46, 70 💬
 45  Selexipag [5] I.v. selexipag; Oral selexipag (uptravi); Selexipag; Selexipag (uptravi); Selexipag, act-293987 (ns-304);  [1] D09994 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [5] 51, 70, 84, 86, 88 💬
 46  Sufentanil [2] Bupivacaïne hcl 0,125% / sufentanil 50 µg flacon à 50 ml; Sufentanil;  [2] D00845
D05938 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2] 70, 280 💬
 47  Sulpiride - [2] D01226
D08549 💬		 [1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [5]  2 ,  6 , 17, 46, 70 💬
 48  Teicoplanin [2] Teicoplanin; Teicoplanin sandoz 200 mg powder and solvent for solution for injection or infusion or oral solution.;  [1] D02142 💬  -  -  [2] 70, 299 💬
 49  Teriparatide [6] Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-methoxy, ether with n-[[[2-[[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl]-2-methylalanyl-teriparatide (2:1); Teriparatide; Teriparatide (forteo); Teriparatide [rdna origin] contains recombinant human parathyroid hormone (1-34); Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker; Teriparatide pen injector;  [1] D06078 💬 [1] PTH1R 💬 [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [7] 46, 65, 68, 70, 71, 235, 274 💬
 50  Titanium [3] Device: interbody cage (titanium); Device: titanium cage; Titanium;  -  -  -  [3] 46, 69, 70 💬
 51  Tramadol [6] Amitriptyline, fluoxetine and tramadol alone (control group); Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group); Tramadol; Tramadol /acetaminophen; Tramadol hydrochloride + acetaminophen; Tramadol with ropivacaine;  [2] D01355
D08623 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [5] 46, 70, 78, 226, 271 💬
 52  Tranexamic acid [3] Tranexamic acid; Tranexamic acid 100 mg/ml; Tranexamic acid injection [cyklokapron];  [1] D01136 💬 [1] PLG 💬 [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [5] 46, 70, 215, 227, 288 💬
 53  Triamcinolone [11] Bladder instillation with triamcinolone acetonide; Bladder instillation without triamcinolone acetonide; Intra plexus triamcinolone and bupivicaine injection; Procedure: celiac block with triamcinolone and bupivicaine; Triamcinolone; Triamcinolone 40 milligrams (kenacort, bristol myers squip); Triamcinolone acetonide; Triamcinolone acetonide and normal saline solution; Triamcinolone hexacetonid (lederspan); Triamcinolone hexacetonide; Triamcinolone hexacetonide (lederspan);  [5] D00385
D00983
D00984
D00985
D06216 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [8] 35, 46, 56, 70, 90, 96, 226, 298 💬
 54  Vancomycin [10] Inhaled vancomycin; Iv vancomycin hydrochloride; Oral vancomycin; Vancomycin; Vancomycin hydrochloride inhalation powder; Vancomycin inhalation powder; Vancomycin pre-treat; Vancomycin pre-treatment; With u-vanco (vancomycin hydrochloride); Without u-vanco (vancomycin hydrochloride);  [2] D00212
D00926 💬		  -  -  [7] 46, 70, 94, 96, 97, 296, 299 💬