Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
4 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
5 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
6 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
7 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
8 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
9 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D00573 D00573 💬 |
Goserelin | 001 [1] 1 💬 |
10 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D04405 D04405 💬 |
Goserelin | 001 [1] 1 💬 |
11 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
12 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
13 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D00573 D00573 💬 |
Goserelin | 001 [1] 1 💬 |
14 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D04405 D04405 💬 |
Goserelin | 001 [1] 1 💬 |
15 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
16 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
17 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
18 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
19 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
20 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
21 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
22 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
23 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
24 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
25 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
26 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
27 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
28 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
29 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
30 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
31 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
32 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
33 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
34 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
SRD5A2 [1] SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 [2] 1 , 2 💬 |
35 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
36 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
37 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
38 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 [2] 1 , 2 💬 |
39 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
40 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |