Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
2 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
3 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
4 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
5 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
6 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
7 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
8 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
9 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
10 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
11 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
12 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
13 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
14 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
15 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
16 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
17 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
18 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
19 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
20 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
21 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
22 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
23 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
24 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
25 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
26 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
27 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
28 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
29 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [2] 62, 109 💬 |
30 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |