Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
ACHE [1] ACHE 💬 |
D00670 D00670 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
2 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
ACHE [1] ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
3 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
4 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
5 | Glycerophospholipid metabolism 💬 1 gene, 6 drugs (DrugBank) and 15 diseases |
ACHE [1] ACHE 💬 |
D00670 D00670 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
6 | Glycerophospholipid metabolism 💬 1 gene, 6 drugs (DrugBank) and 15 diseases |
ACHE [1] ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
7 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CALCA [1] CALCA 💬 |
D11055 D11055 💬 |
Fremanezumab | 124 [2] 124, 226 💬 |
8 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
9 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
10 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
11 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
12 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
13 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
14 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CALCA [1] CALCA 💬 |
D11055 D11055 💬 |
Fremanezumab | 124 [2] 124, 226 💬 |