Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00354 D00354 💬 |
Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D05775 D05775 💬 |
Rufinamide | 144 [1] 144 💬 |
5 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
6 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
7 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
8 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
9 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
10 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
11 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
12 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
13 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
14 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
15 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
16 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
17 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
18 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
19 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
20 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
21 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
22 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
KCNQ1 [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
23 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
24 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
25 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D08170 D08170 💬 |
Melatonin | 006 [11] 6 , 8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬 |
26 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 [1] GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
27 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 [1] GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
28 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
29 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
30 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
31 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
32 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [7] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
33 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
34 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00354 D00354 💬 |
Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬 |
35 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D05775 D05775 💬 |
Rufinamide | 144 [1] 144 💬 |
36 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [20] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
37 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
38 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
39 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
40 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
41 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [11] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
42 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
43 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
44 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
45 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
46 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
47 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
48 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
49 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
50 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
51 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
52 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
53 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [3] CACNA1C, GRIA1, GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
54 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
55 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
56 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA2 [2] CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
57 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
58 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
59 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 [2] CNR1, CNR2 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
60 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
61 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [25] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
62 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
63 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
64 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D08170 D08170 💬 |
Melatonin | 006 [11] 6 , 8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬 |
65 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
66 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
67 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
68 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA2 [2] CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
69 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
70 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
71 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
72 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
73 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
74 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
75 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 12 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
76 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
77 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
78 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
79 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
80 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
81 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
82 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
83 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
84 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
85 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
86 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
87 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
88 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [3] 140, 144, 145 💬 |
89 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
90 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
91 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00354 D00354 💬 |
Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬 |
92 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D05775 D05775 💬 |
Rufinamide | 144 [1] 144 💬 |
93 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
94 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
95 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 [1] GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
96 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 [1] GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
97 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
98 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [5] 6 , 140, 144, 156, 193 💬 |
99 | Vibrio cholerae infection 💬 3 genes, 9 drugs (DrugBank) and 7 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |