Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
2 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
3 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
4 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
5 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
6 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
7 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
8 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
9 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
10 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
11 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
12 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
13 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
14 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
15 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
16 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
17 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
18 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
19 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
20 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
21 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
22 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
23 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
24 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
25 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
26 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
27 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
28 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
29 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
30 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
31 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
32 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
33 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
34 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
35 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
36 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
37 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
38 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
39 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
40 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
41 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
42 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
43 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |